Schwann Cell Development And Pathology
Download Schwann Cell Development And Pathology full books in PDF, epub, and Kindle. Read online free Schwann Cell Development And Pathology ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
| Author | : Kazunori Sango |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 178 |
| Release | : 2014-02-13 |
| Genre | : Medical |
| ISBN | : 4431547649 |
This book presents recent topics on the development, differentiation, and myelination of Schwann cells, as well as pathological mechanisms and therapeutic approaches for peripheral neuropathies, such as Charcot–Marie–Tooth diseases, amyloid polyneuropathy, immune-mediated neuropathy and diabetic neuropathy. The rapid progress of molecular biological techniques in the last decades, especially for RNA techniques and gene modification technologies have allowed us to investigate the pathobiology of Schwann cells in vivo and in vitro. Studies combining recent stem cell biology with recent biotechnology, which is now closely linked to physicochemical fields, further explain how Schwann cell lineages develop a process that has long been thought to be very complicated in vivo. The findings contribute to the elucidation of fundamental mechanisms during development and under pathological conditions. We now know that these are closely tied to each other. This book also introduces unique coculture systems to reproduce the neuron–Schwann cell interplay during development, degeneration, and regeneration. Up-to-date research topics with high-quality immunofluorescence and electron micrographs introduced by young and energetic contributors are sure to arouse the readers' interest in Schwann cell biology. Discussion from the viewpoint of basic and clinical neuroscience makes the book educational for researchers, medical students and young clinicians.
| Author | : Patricia Armati |
| Publisher | : Cambridge University Press |
| Total Pages | : 185 |
| Release | : 2007-02-15 |
| Genre | : Medical |
| ISBN | : 1139462091 |
Schwann cells are a diverse group of cells formed from neural crest cells. They are essential components of the peripheral nerves of both vertebrate and invertebrate nervous systems. The diversity of Schwann cell subsets and function is seen in those Schwann cells that form myelin - that uniquely specialised part of the plasma membrane that spirals around axonal lengths to myelinate the peripheral nerves. The Biology of Schwann Cells concentrates on the cells of mammals and in particular humans. It covers the distinction between compact and non-compact myelin in depth, along with the perisynaptic cells which form the partnership between nerve terminals and muscle fibre. Developmental aspects are discussed alongside differentiation, and the genetics of the cells in health and disease. With chapters from world-renowned experts, this book is aimed at postgraduates and researchers in neuroscience and neurology and anyone involved in the study of peripheral nerves.
| Author | : H. Mei Liu |
| Publisher | : |
| Total Pages | : 328 |
| Release | : 1981 |
| Genre | : Medical |
| ISBN | : |
Biology and Pathology of Nerve Growth ...
| Author | : Bernhard H.J. Juurlink |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 392 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 1461559499 |
Proceedings of the Fourth International Altschul Symposium held at Saskatoon, Saskatchewan, Canada, June 27-29, 1996
| Author | : Patricia Armati |
| Publisher | : Cambridge University Press |
| Total Pages | : |
| Release | : 2010-10-21 |
| Genre | : Medical |
| ISBN | : 1139491717 |
Traditionally, oligodendrocytes have been assumed to play a minor supporting role in the central nervous system and their importance has generally been overlooked. For the first time, this book provides a dedicated review of all of the major aspects of oligodendrocyte biology, including development, organization, genetics, and immunobiology. Later chapters emphasize the importance of this underestimated cell to the mammalian central nervous system by exploring the role of myelin synthesis and maintenance in neural disease and repair. Particular attention is paid to multiple sclerosis (MS), arguably the prime example of an acquired demyelinating disease, with detailed examinations of the current concepts regarding demyelination, oligodendroglial damage, and remyelination in MS lesions.
| Author | : |
| Publisher | : Academic Press |
| Total Pages | : 993 |
| Release | : 2013-05-06 |
| Genre | : Science |
| ISBN | : 0123973481 |
The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 1 offers 48 high level articles devoted mainly to patterning and cell type specification in the developing central and peripheral nervous systems. - Series offers 144 articles for 2904 full color pages addressing ways in which the nervous system and its components develop - Features leading experts in various subfields as Section Editors and article Authors - All articles peer reviewed by Section Editors to ensure accuracy, thoroughness, and scholarship - Volume 1 sections include coverage of mechanisms which: control regional specification, regulate proliferation of neuronal progenitors and control differentiation and survival of specific neuronal subtypes, and controlling development of non-neural cells
| Author | : Oswald Steward |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 266 |
| Release | : 2012-12-06 |
| Genre | : Medical |
| ISBN | : 1461235405 |
The field of cellular, molecular, and developmental neuroscience repre sents the interface between the three large, well established fields of neu roscience, cell biology, and molecular biology. In the last 10 to 15 years, this new field has emerged as one of the most rapidly growing and exciting subdisciplines of neuroscience. It is now becoming possible to understand many aspects of nervous system function at the molecular level, and there already are dramatic applications of this information to the treatment of nervous system injury, disease, and genetic disorders. Moreover, there is great optimism that new strategies will emerge soon as a result of the explosion of information. This book was written to introduce students to the major issues, ex perimental strategies, and current knowledge base in cellular, molecular, and developmental neuroscience. The concept for the book arose from a section of an introductory neuroscience course given to first-year medical students at the University of Virginia School of Medicine. The text pre sumes a basic, but not detailed, understanding of nervous system orga nization and function, and a background in biology. It is intended as an appropriate introductory text for first-year medical students or graduate students in neuroscience, neurobiology, psychobiology, or related pro grams;··and for advanced undergraduate students with appropriate back ground in biology and neuroscience. While some of the specific information presented undoubtedly will be outdated rapidly, the "gestalt" of this emerging field of inquiry as presented here should help the beginning stu dent organize new information.
| Author | : Kwok-Fai So |
| Publisher | : Academic Press |
| Total Pages | : 0 |
| Release | : 2015-02-06 |
| Genre | : Science |
| ISBN | : 9780128017326 |
Neural Regeneration provides an overview of cutting-edge knowledge on a broad spectrum of neural regeneration, including: Neural regeneration in lower vertebrates Neural regeneration in the peripheral nervous system Neural regeneration in the central nervous system Transplantation-mediated neural regeneration Clinical and translational research on neural regeneration The contributors to this book are experts in their fields and work at distinguished institutions in the United States, Canada, Australia, and China. Nervous system injuries, including peripheral nerve injuries, brain and spinal cord injuries, and stroke affect millions of people worldwide every year. As a result of this high incidence of neurological injuries, neural regeneration and repair is becoming a rapidly growing field dedicated to the new discoveries to promote structural and functional recoveries based on neural regeneration. The ultimate goal is to translate the most optimal regenerative strategies to treatments of human nervous system injuries. This valuable reference book is useful for students, postdoctors, and basic and clinical scientists who are interested in neural regeneration research.
| Author | : Heinz Redl |
| Publisher | : Springer |
| Total Pages | : 0 |
| Release | : 2017-02-16 |
| Genre | : Technology & Engineering |
| ISBN | : 9783319088303 |
This reference work presents the origins of cells for tissue engineering and regeneration, including primary cells, tissue-specific stem cells, pluripotent stem cells and trans-differentiated or reprogrammed cells. There is particular emphasis on current understanding of tissue regeneration based on embryology and evolution studies, including mechanisms of amphibian regeneration. The book covers the use of autologous versus allogeneic cell sources, as well as various procedures used for cell isolation and cell pre-conditioning , such as cell sorting, biochemical and biophysical pre-conditioning, transfection and aggregation. It also presents cell modulation using growth factors, molecular factors, epigenetic approaches, changes in biophysical environment, cellular co-culture and other elements of the cellular microenvironment. The pathways of cell delivery are discussed with respect to specific clinical situations, including delivery of ex vivo manipulated cells via local and systemic routes, as well as activation and migration of endogenous reservoirs of reparative cells. The volume concludes with an in-depth discussion of the tracking of cells in vivo and their various regenerative activities inside the body, including differentiation, new tissue formation and actions on other cells by direct cell-to-cell communication and by secretion of biomolecules.
| Author | : Nicole Le Douarin |
| Publisher | : Cambridge University Press |
| Total Pages | : 494 |
| Release | : 1999-11-28 |
| Genre | : Medical |
| ISBN | : 9780521620109 |
This 1999 edition of The Neural Crest contains comprehensive information about the neural crest, a structure unique to the vertebrate embryo, which has only a transient existence in early embryonic life. The ontogeny of the neural crest embodies the most important issues in developmental biology, as the neural crest is considered to have played a crucial role in evolution of the vertebrate phylum. Data that analyse neural crest ontogeny in murine and zebrafish embryos have been included in this revision. This revised edition also takes advantage of recent advances in our understanding of markers of neural crest cell subpopulations, and a full chapter is now devoted to cell lineage analysis. The major research breakthrough since the first edition has been the introduction of molecular biology to neural crest research, enabling an elucidation of many molecular mechanisms of neural crest development. This book is essential reading for students and researchers in developmental biology, cell biology, and neuroscience.
