This book presents the proceedings of the international academic workshop on “Early Navigation in the Asia-Pacific Region: A Maritime Archaeological Perspective” held from June 21-23, 2013 at Harvard University campus and organized by Harvard-Yenching Institute. It includes high-quality papers focusing on the historical shipwrecks investigated by underwater archaeologists from Eastern Asian, including southern China, Vietnam, Thailand, the Philippines, Indonesia and Malaysia, and North America, including California, Oregon and Washington in the US, as well as Mexico. These investigations reveal the history of the early pan-Pacific navigation and maritime globalization from the 16th to the 18th century, covering the background and formation, concept and practice, as well as the results and influence of this early globalization and global economy, emphasizing the maritime archaeological evidence of Spanish exploration of transportation between East Asia and North America. The book provides an excellent opportunity for maritime archaeologists from both sides of the Pacific to share the latest findings and new developments in maritime archaeological exploration. It discusses 16-18th century nautical trade and maritime cultural history and provides a comprehensive overview of research work in the Asia-Pacific region.