Safety Assessment Of Cosmetics In Europe
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| Author | : Vera Rogiers |
| Publisher | : Karger Medical and Scientific Publishers |
| Total Pages | : 235 |
| Release | : 2008 |
| Genre | : Medical |
| ISBN | : 3805586558 |
This volume of Current Problems in Dermatology presents the reader with a portrait of the scientific background of the complex process of safety assessment of cosmetics as well as information on European cosmetic legislation. A practical approach to the search for toxicity data on cosmetic ingredients and a compilation of the legally required technical dossier of a finished cosmetic product as well as an in-depth analysis of the safety assessment of cosmetic ingredients performed at the EU level by the Scientific Committee on Consumer Products (SCCP) are available. The current status of 3R alternatives to animal testing and the extent to which they are implemented by the cosmetic industry and considered by the SCCP in the risk assessment process is discussed. As such, guidance is provided in relation to the manifold challenges cosmetic safety assessors are faced with in the current EU regulatory setting.In this valuable handbook, qualified cosmetic safety assessors, suppliers of raw materials, dermatologists and pharmacists, toxicologists as well as EU officials and administrators dealing with cosmetics will find relevant information on the European cosmetic legislation, the compilation of cosmetic technical dossiers, toxicological database searches, and the availability and use of alternative methods in the field of cosmetics.
| Author | : |
| Publisher | : Council of Europe |
| Total Pages | : 0 |
| Release | : 2008 |
| Genre | : Health & Fitness |
| ISBN | : 9789287162984 |
Ingredients are used in cosmetics to give them specific properties. Certain ingredients, so called active ingredients, may produce pharmacological or toxic effects under certain conditions. Cosmetic products containing such ingredients may pose a health risk both because of their potential toxicity and because they may mask underlying serious diseases and consequently cause a dangerous delay in diagnosis and treatment. The objective of this study is to give safety information on certain active ingredients which give raise to toxicological concerns and for which restrictions of use in cosmetics should be considered. Monographs were prepared for 45 active ingredients for which no specific regulations exist.
| Author | : Hajime Kojima |
| Publisher | : Springer |
| Total Pages | : 136 |
| Release | : 2018-12-27 |
| Genre | : Medical |
| ISBN | : 9811324476 |
This open access book presents recent advances in the pure sciences that are of significance in the quest for alternatives to the use of animals in research and describes a variety of practical applications of the three key guiding principles for the more ethical use of animals in experiments – replacement, reduction, and refinement, collectively known as the 3Rs. Important examples from across the world of implementation of the 3Rs in the testing of cosmetics, chemicals, pesticides, and biologics, including vaccines, are described, with additional information on relevant regulations. The coverage also encompasses emerging approaches to alternative tests and the 3Rs. The book is based on the most informative contributions delivered at the Asian Congress 2016 on Alternatives and Animal Use in the Life Sciences. It will be of value for those working in R&D, for graduate students, and for educators in various fields, including the pharmaceutical and cosmetic sciences, pharmacology, toxicology, and animal welfare. The free, open access distribution of Alternatives to Animal Testing is enabled by the Creative Commons Attribution license in International version 4: CC BY 4.0.
| Author | : Wilfried Rähse |
| Publisher | : John Wiley & Sons |
| Total Pages | : 502 |
| Release | : 2020-01-13 |
| Genre | : Science |
| ISBN | : 3527343989 |
A guide to cosmetic creams that focuses on formulation, production, and safety concerns Cosmetic Creams: Development, Manufacture and Marketing of Effective Skin Care Products puts the focus on the structure and formulation of a cosmetic cream, the production process, the effect of each ingredient, as well as safety considerations. Comprehensive in scope, the book contains a basic definition of cosmetics and describes the types of skin creams currently on the market, the major ingredients used, and example compositions. The author, Wilfried Rähse?a noted expert on the topic?offers guidelines for estimating manufacturing costs and includes procedures for an effective safety assessment. The book contains information on various aspects of skin penetration and production and covers issues like materials used and hygienic packaging. In addition, Rähse reviews legal regulations with an emphasis on the European market. He discusses GMP and EHEDG directives. This important book: -Offers a comprehensive resource that explores all aspects of cosmetic cream manufacturing and marketing -Provides valuable guidelines for practitioners in the field -Covers the underlying technologies of cosmetic creams -Includes a review of raw material and manufacturing costs, hygiene and safety, and legal regulations -Written by an author with more than 30 years? experience in the industry Written for cosmetic chemists, chemists in industry, chemical engineers, dermatologists, Cosmetic Creams: Development, Manufacture and Marketing of Effective Skin Care Products, offers a unique industrial perspective of the topic that is comprehensive in scope.
| Author | : Mark T. D. Cronin |
| Publisher | : Royal Society of Chemistry |
| Total Pages | : 689 |
| Release | : 2010 |
| Genre | : Medical |
| ISBN | : 1849730040 |
This book defines the use of computational approaches to predict the environmental toxicity and human health effects of organic chemicals.
| Author | : Great Britain |
| Publisher | : |
| Total Pages | : 619 |
| Release | : 2018-12-12 |
| Genre | : |
| ISBN | : 9780111176368 |
Enabling power: European Union (Withdrawal) Act 2018, s. 8 (1), sch. 7, para. 21. Issued: 14.12.2018. Sifted: -. Made: -. Laid: -. Coming into force: In accord. with reg. 1. Effect: 1973 c. 43; 1985 c. 72; 1987 c. 43; S.I. 1977/932; 1988/186, 2039; 1998/2307; 2001/1701; 2005/1803, 3117; 2006/659; 2008/1597; 2009/2824, 3155; 2011/1881; 2014/1638; 2015/356, 398, 1553; 2016/1091, 1092, 1093, 1101, 1105, 1107, 1152, 1153; 2017/737, 1206; S.R. 2013/48; 2016/366; 2017/90 amended. Territorial extent & classification: E/W/S/NI. For approval by resolution of each House of Parliament. EC note: These Regulations are made in order to address failures of retained EU law. These Regulations make amendments to legislation in the field of product safety and metrology. Part 2 amends primary legislation, Part 3 amends subordinate legislation, Part 4 amends subordinate legislation applying to Northern Ireland, Part 5 amends retained direct EU legislation and Part 6 makes revocations
| Author | : David Henry Smyth |
| Publisher | : |
| Total Pages | : 228 |
| Release | : 1978 |
| Genre | : Animal experimentation |
| ISBN | : |
| Author | : Nava Dayan |
| Publisher | : John Wiley & Sons |
| Total Pages | : 432 |
| Release | : 2020-09-01 |
| Genre | : Medical |
| ISBN | : 1119592232 |
The book provides a comprehensive detailed summary of current status on skin microbiome research in health and disease as well as key regulatory and legal aspects. In the past decade, interest and technology have greatly advanced to unravel the nature and effect of skin microbiome on our health. Diseases such as atopic dermatitis and acne are at the forefront of this research, but also other conditions such as skin cancer are under investigation. In addition, mapping of the skin microbiome has gone from basic to more detailed with attempts to correlate it to various ages, ethnicities and genders. In parallel to mapping it, a great deal of research is dedicated to understanding its functionality and communication (and hence effect) on human cells. The Skin Microbiome Handbook is a summary of current status of knowledge, research tools and approaches in skin microbiome, in health and disease. It contains the following categories: healthy skin microbiome and oral-skin interaction; skin microbiome observational research; skin microbiome in disequilibrium and disease; skin's innate immunity; testing and study design; regulatory and legal aspects for skin microbiome related products. The 18 chapters of the book are written by carefully selected leaders in the academia and industry exhibiting extensive experience and understanding in the areas of interest.
| Author | : William Waggoner |
| Publisher | : CRC Press |
| Total Pages | : 350 |
| Release | : 1989-11-27 |
| Genre | : Medical |
| ISBN | : 9780824779412 |
| Author | : Alberto Mantovani |
| Publisher | : Royal Society of Chemistry |
| Total Pages | : 539 |
| Release | : 2020-12-08 |
| Genre | : Science |
| ISBN | : 1839160837 |
Insight into the role of hormones, particularly estrogen and testosterone, in health and disease etiology – including interactions with other hormone pathways – has dramatically changed. Estrogen and androgen receptors, with their polymorphisms, are key molecules in all tissues and are involved in a number of homeostatic mechanisms but also pathological processes including carcinogenesis and the development of metabolic and neurological disorders such as diabetes and Alzheimer’s disease. Endocrine disrupting chemicals (EDCs) can interfere with the endocrine (hormone) systems at certain dosages and play a key role in the pathology of disease. Most known EDCs are manmade and are therefore an increasing concern given the number commonly found in household products and the environment. This book will cover the mechanisms of EDC pathology across the spectrum of disease, as well as risk assessment and government and legal regulation to provide a holistic view of the current issues and cutting-edge research in the topic. With contributions from global leaders in the field, this book will be an ideal reference for toxicologists, endocrinologists and researchers interested in developmental biology, regulatory toxicology and the interface between environment and human health.
