Second Supplements to the 2nd Edition of Rodd's Chemistry of Carbon Compounds

Second Supplements to the 2nd Edition of Rodd's Chemistry of Carbon Compounds
Author: Sainsbury
Publisher: Elsevier Science
Total Pages: 388
Release: 2001-11-12
Genre: Science
ISBN: 9780444509017

To date, the second edition of the Rodd's series consists of 71 volumes and over 30,000 pages.Rodd's Chemistry of Carbon Compounds is continuing with a short series of topical volumes on emerging subjects that are not covered in detail in the main volumes. The first two topical volumes will cover organic electrochemistry and asymmetric catalysis.Asymmetric synthesis initiated by metal catalysts is, of course, not a new topic and asymmetric reduction and epoxidation of alkenes, in particular, are major subject areas covered widely in the Supplements to the 2nd Edition of Rodd's Chemistry of the Carbon Compounds. However, there has been a huge increase in the use of asymmetrically catalysed reactions in other areas in the last five years or so, and this is why this subject has been specially selected to form the content of a Topical Volume.The book does not dwell at length upon topics of great importance such as Sharpless epoxidation, or upon the control of stereochemistry through catalytic reduction of double bonds. These subjects have been exhaustively surveyed elsewhere. Instead it concentrates upon those topics that appear to be 'up and coming'. Only time can tell if all will be adopted as widely and successfully as their predecessors, but it now seems clear that chemists have at their disposal an ever increasing and formidable array of methods to effect total topological control of even the most complex target molecule.This book, written by some of the best young chemists, concentrating upon work in their own subject areas, provides a snap shot of the current 'state of play' in this a key test of their scientific ingenuity. In the Cumulative Index will be found the entire contents of the 2nd edition and both of the supplements, together with a list of main titles and chapter headings for each volume. This index will enable the reader to make better and easier searches in Rodd, which is the most compact, comprehensive and accessible survey of organic chemistry ever written.

Modern Carbonyl Olefination

Modern Carbonyl Olefination
Author: Takeshi Takeda
Publisher: John Wiley & Sons
Total Pages: 365
Release: 2006-03-06
Genre: Science
ISBN: 352760538X

While this important reaction class is among the most important and most widely used in organic chemistry, this is the first book to summarize the many different olefination methods, including: * Wittig reaction * Peterson reaction * Julia olefination * Utilizing the Tebbe and related reagents * Low-valent chromium, zinc or titanium mediated olefination * McMurry coupling plus the related reactions in each case and the application to asymmetric synthesis. It thus collates in one ready reference the current level of knowledge as well as new developments in this constantly evolving field -- information which until now has been dispersed throughout the literature.

Principles and Methods for Accelerated Catalyst Design and Testing

Principles and Methods for Accelerated Catalyst Design and Testing
Author: E.G. Derouane
Publisher: Springer Science & Business Media
Total Pages: 504
Release: 2012-12-06
Genre: Science
ISBN: 9401005540

High throughput experimentation has met great success in drug design but it has, so far, been scarcely used in the field ofcatalysis. We present in this book the outcome of a NATO ASI meeting that was held in Vilamoura, Portugal, between July 15 and 28, 2001, with the objective of delineating and consolidating the principles and methods underpinning accelerated catalyst design, evaluation, and development. There is a need to make the underlying principles of this new methodology more widely understood and to make it available in a coherent and integrated format. The latter objective is particularly important to the young scientists who will constitute the new catalysis researchers generation. Indeed, this field which is at the frontier offundamental science and may be a renaissance for catalysis, is one which is much more complex than classical catalysis itself. It implies a close collaboration between scientists from many disciplines (chemistry, physics, chemical and mechanical engineering, automation, robotics, and scientific computing in general). In addition, this emerging area of science is also of paramount industrial importance, as progress in this area would collapse the time necessary to discover new catalysts or improve existing ones.

Asymmetric Synthesis of Nitrogen Heterocycles

Asymmetric Synthesis of Nitrogen Heterocycles
Author: Jacques Royer
Publisher: John Wiley & Sons
Total Pages: 425
Release: 2009-08-04
Genre: Science
ISBN: 3527625518

Here, all aspects of the topic are presented in a compact manner. The book is clearly structured, and divided into two sections -- asymmetric synthesis of heterocycles containing only one nitrogen and that of those with more than one nitrogen as a heteroatom -- such that the necessary information may be found at a glance. The international team of authors provides important experimental procedures, including industrial applications. Essential for synthetic chemists in pharmaceutical and agrochemical chemistry.

Transition Metal-Catalyzed Carbene Transformations

Transition Metal-Catalyzed Carbene Transformations
Author: Jianbo Wang
Publisher: John Wiley & Sons
Total Pages: 450
Release: 2021-12-20
Genre: Science
ISBN: 3527829156

Presents an up-to-date overview of the rapidly growing field of carbene transformations Carbene transformations have had an enormous impact on catalysis and organometallic chemistry. With the growth of transition metal-catalyzed carbene transformations in recent decades, carbene transformations are today an important compound class in organic synthesis as well as in the pharmaceutical and agrochemical industries. Edited by leading experts in the field, Transition Metal-Catalyzed Carbene Transformations is a thorough summary of the most recent advances in the rapidly expanding research area. This authoritative volume covers different reaction types such as ring forming reactions and rearrangement reactions, details their conditions and properties, and provides readers with accurate information on a wide range of carbene reactions. Twelve in-depth chapters address topics including carbene C-H bond insertion in alkane functionalization, the application of engineered enzymes in asymmetric carbene transfer, progress in transition-metal-catalyzed cross-coupling using carbene precursors, and more. Throughout the text, the authors highlight novel catalytic systems, transformations, and applications of transition-metal-catalyzed carbene transfer. Highlights the dynamic nature of the field of transition-metal-catalyzed carbene transformations Summarizes the catalytic radical approach for selective carbene cyclopropanation, high enantioselectivity in X-H insertions, and bio-inspired carbene transformations Introduces chiral N,N'-dioxide and chiral guanidine-based catalysts and different transformations with gold catalysis Discusses approaches in cycloaddition reactions with metal carbenes and polymerization with carbene transformations Outlines multicomponent reactions through gem-difunctionalization and transition-metal-catalyzed cross-coupling using carbene precursors Transition Metal-Catalyzed Carbene Transformations is essential reading for all chemists involved in organometallics, including organic and inorganic chemists, catalytic chemists, and chemists working in industry.

Aromaticity in Heterocyclic Compounds

Aromaticity in Heterocyclic Compounds
Author: Tadeusz Marek Krygowski
Publisher: Springer Science & Business Media
Total Pages: 355
Release: 2009-01-30
Genre: Science
ISBN: 3540683291

Heterocyclic chemistry is the biggest branch of chemistry covering two-thirds of the chemical literature. Aromaticity in Heterocyclic Compounds covers hot topics of frontier research summarized by reputed scientists in the field.