The RNA World
Author | : Raymond F. Gesteland |
Publisher | : |
Total Pages | : 744 |
Release | : 1999 |
Genre | : Science |
ISBN | : |
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Author | : Raymond F. Gesteland |
Publisher | : |
Total Pages | : 744 |
Release | : 1999 |
Genre | : Science |
ISBN | : |
Author | : David Elliott |
Publisher | : Oxford University Press |
Total Pages | : 445 |
Release | : 2017-01-31 |
Genre | : Science |
ISBN | : 019107103X |
RNA plays a central, and until recently, somewhat underestimated role in the genetics underlying all forms of life on earth. This versatile molecule not only plays a crucial part in the synthesis of proteins from a DNA template, but is also intrinsically involved in the regulation of gene expression, and can even act as a catalyst in the form of a ribozyme. This latter property has led to the hypothesis that RNA - rather than DNA - could have played an essential part in the origin of life itself. This landmark text provides a systematic overview of the exciting and rapidly moving field of RNA biology. Key pioneering experiments, which provided the underlying evidence for what we now know, are described throughout, while the relevance of the subject to human disease is highlighted via frequent boxes. For the second edition of Molecular Biology of RNA, more introductory material has been incorporated at the beginning of the text, to aid students studying the subject for the first time. Throughout the text, new material has been included - particularly in relation to RNA binding domains, non-coding RNAs, and the connection between RNA biology and epigenetics. Finally, a new closing chapter discusses how exciting new technologies are being used to explore current topical areas of research.
Author | : Raymond F. Gesteland |
Publisher | : CSHL Press |
Total Pages | : 774 |
Release | : 2006 |
Genre | : Science |
ISBN | : 0879697393 |
Recent studies on the activities of RNA in the cell have revolutionized our understanding of the many roles played by this molecule. The first two editions of The RNA World(1993, 1999) shed light on the pre–biotic era dominated by this versatile molecule, and provided an overview of the state of RNA research at the time. The new third edition of The RNA Worldupdates this perspective, describing the vast array of newly discovered roles for RNA in the modern world. The updated original chapters are supplemented with new chapters on RNA–protein complexes, snRNPs and snoRNPs, telomerase RNA, RNAi, microRNAs, noncoding RNA, and many other subjects. This book is essential reading for anyone interested in the biology of nucleic acids and gene regulation and a valuable resource for teaching these concepts.
Author | : Esteban Domingo |
Publisher | : Elsevier |
Total Pages | : 573 |
Release | : 2008-06-23 |
Genre | : Science |
ISBN | : 0080564968 |
New viral diseases are emerging continuously. Viruses adapt to new environments at astounding rates. Genetic variability of viruses jeopardizes vaccine efficacy. For many viruses mutants resistant to antiviral agents or host immune responses arise readily, for example, with HIV and influenza. These variations are all of utmost importance for human and animal health as they have prevented us from controlling these epidemic pathogens. This book focuses on the mechanisms that viruses use to evolve, survive and cause disease in their hosts. Covering human, animal, plant and bacterial viruses, it provides both the basic foundations for the evolutionary dynamics of viruses and specific examples of emerging diseases. - NEW - methods to establish relationships among viruses and the mechanisms that affect virus evolution - UNIQUE - combines theoretical concepts in evolution with detailed analyses of the evolution of important virus groups - SPECIFIC - Bacterial, plant, animal and human viruses are compared regarding their interation with their hosts
Author | : John Scales Avery |
Publisher | : World Scientific |
Total Pages | : 277 |
Release | : 2012-05-21 |
Genre | : Science |
ISBN | : 9814401250 |
Information Theory and Evolution discusses the phenomenon of life, including its origin and evolution (and also human cultural evolution), against the background of thermodynamics, statistical mechanics, and information theory. Among the central themes is the seeming contradiction between the second law of thermodynamics and the high degree of order and complexity produced by living systems. This paradox has its resolution in the information content of the Gibbs free energy that enters the biosphere from outside sources, as the author will show. The role of information in human cultural evolution is another focus of the book.The first edition of Information Theory and Evolution made a strong impact on thought in the field by bringing together results from many disciplines. The new second edition offers updated results based on reports of important new research in several areas, including exciting new studies of the human mitochondrial and Y-chromosomal DNA. Another extensive discussion featured in the second edition is contained in a new appendix devoted to the relationship of entropy and Gibbs free energy to economics. This appendix includes a review of the ideas of Alfred Lotka, Frederick Soddy, Nicholas Georgiescu-Roegen and Herman E. Daly, and discusses the relevance of these ideas to the current economic crisis.The new edition discusses current research on the origin of life, the distinction between thermodynamic information and cybernetic information, new DNA research and human prehistory, developments in current information technology, and the relationship between entropy and economics.
Author | : David E. Metzler |
Publisher | : Academic Press |
Total Pages | : 968 |
Release | : 2001-03-23 |
Genre | : Medical |
ISBN | : 0124925405 |
Biochemistry: The Chemical Reactions of Living Cells is a well-integrated, up-to-date reference for basic biochemistry, associated chemistry, and underlying biological phenomena. Biochemistry is a comprehensive account of the chemical basis of life, describing the amazingly complex structures of the compounds that make up cells, the forces that hold them together, and the chemical reactions that allow for recognition, signaling, and movement. This book contains information on the human body, its genome, and the action of muscles, eyes, and the brain. It also features: thousands of literature references that provide introduction to current research as well as historical background; twice the number of chapters of the first edition; and each chapter contains boxes of information on topics of general interest. -- Publisher description.
Author | : Thomas F. Heinze |
Publisher | : Chick Publications |
Total Pages | : 159 |
Release | : 2011 |
Genre | : Religion |
ISBN | : 0758908598 |
Could life have formed in the Primordial Soup billions of years ago? Evolutionists claim that simple chemicals became concentrated in ancient oceans, forming an organic broth which eventually produced living cells. Is this possible? In 1953 Stanley Miller became famous for his experiment which produced amino acids by passing a spark through gasses which contained the elements that make up amino acids. Evolutionists hoped their students would believe without question that amino acids would produce life. But Heinze reveals the facts evolutionists won't tell you. The amino acids produced would not work in any living things. The more recently suggested steps in Chemical evolution will not take place either. The idea is scientifically bankrupt, and the foundation of evolutionary thinking is destroyed. Full of quotes from the best known scientists in the field, How Life Began is a great gift for students, teachers and school libraries. Learn how the scientific facts speak powerfully of an intelligent Creator, without whom life could never have begun. Learn how to know Him personally.
Author | : Franklin M. Harold |
Publisher | : |
Total Pages | : 320 |
Release | : 2003 |
Genre | : Science |
ISBN | : 0195163389 |
Schrodinger's riddle -- The quality of life -- Cells in nature and in theory -- Molecular logic -- A (almost) comprehensible cell -- It takes a cell to make a cell -- Morphogenesis: where form and function meet -- The advance of the microbes -- By descent with modification -- So what is life? -- Searching for the beginning.
Author | : Roland K. Hartmann |
Publisher | : John Wiley & Sons |
Total Pages | : 1370 |
Release | : 2015-06-22 |
Genre | : Science |
ISBN | : 3527327762 |
The second edition of a highly acclaimed handbook and ready reference. Unmatched in its breadth and quality, around 100 specialists from all over the world share their up-to-date expertise and experiences, including hundreds of protocols, complete with explanations, and hitherto unpublished troubleshooting hints. They cover all modern techniques for the handling, analysis and modification of RNAs and their complexes with proteins. Throughout, they bear the practising bench scientist in mind, providing quick and reliable access to a plethora of solutions for practical questions of RNA research, ranging from simple to highly complex. This broad scope allows the treatment of specialized methods side by side with basic biochemical techniques, making the book a real treasure trove for every researcher experimenting with RNA.
Author | : Thomas Dandekar |
Publisher | : Springer Science & Business Media |
Total Pages | : 234 |
Release | : 2012-12-06 |
Genre | : Science |
ISBN | : 3642562981 |
RNA Motifs and Regulatory Elements is the new edition of the successful book, "Regulatory RNA". It alerts the reader to the importance of regulatory RNA elements for the many different areas of cellular life. The computational and experimental methods and tools to search for new interesting regulatory RNA structures are explained and compared. The knowledge on regulatory RNA structures and elements already available is concisely summarized as well as catalogued. In addition, interesting RNA elements are analyzed in detail regarding their dynamics, regulation, and as a dominant topic of current resarch in molecular biology, including areas such as RNA mediated regulation of gene-expression, DNA/RNA chip data, and ribozymes, splicing, or telomerases in aging. Medical implications are also covered. Future progress and research are finally outlined.