Molecular Biology and Pathogenicity of Mycoplasmas

Molecular Biology and Pathogenicity of Mycoplasmas
Author: Shmuel Razin
Publisher: Springer Science & Business Media
Total Pages: 574
Release: 2007-05-08
Genre: Science
ISBN: 0306476061

was the result of the efforts of Robert Cleverdon. The rapidly developing discipline of molecular biology and the rapidly expanding knowledge of the PPLO were brought together at this meeting. In addition to the PPLO specialists, the conference invited Julius Marmur to compare PPLO DNA to DNA of other organisms; David Garfinkel, who was one of the first to develop computer models of metabolism; Cyrus Levinthal to talk about coding; and Henry Quastler to discuss information theory constraints on very small cells. The conference was an announcement of the role of PPLO in the fundamental understanding of molecular biology. Looking back 40-some years to the Connecticut meeting, it was a rather bold enterprise. The meeting was international and inter-disciplinary and began a series of important collaborations with influences resonating down to the present. If I may be allowed a personal remark, it was where I first met Shmuel Razin, who has been a leading figure in the emerging mycoplasma research and a good friend. This present volume is in some ways the fulfillment of the promise of that early meeting. It is an example of the collaborative work of scientists in building an understanding of fundamental aspects of biology.

Mechanisms of Vascular Disease

Mechanisms of Vascular Disease
Author: Robert Fitridge
Publisher: University of Adelaide Press
Total Pages: 589
Release: 2011
Genre: Medical
ISBN: 1922064009

New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

The Science and Applications of Synthetic and Systems Biology

The Science and Applications of Synthetic and Systems Biology
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 570
Release: 2011-12-30
Genre: Science
ISBN: 0309219396

Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.

Acute & Chronic Wounds

Acute & Chronic Wounds
Author: Ruth A. Bryant
Publisher: Elsevier Health Sciences
Total Pages: 671
Release: 2012-01-01
Genre: Medical
ISBN: 0323069436

Rev. ed. of: Acute and chronic wounds / [edited by] Ruth A. Bryant, Denise P. Nix. 3rd ed. c2007.

Handbook of Single-Molecule Biophysics

Handbook of Single-Molecule Biophysics
Author: Peter Hinterdorfer
Publisher: Springer Science & Business Media
Total Pages: 634
Release: 2009-12-24
Genre: Science
ISBN: 0387764976

This handbook describes experimental techniques to monitor and manipulate individual biomolecules, including fluorescence detection, atomic force microscopy, and optical and magnetic trapping. It includes single-molecule studies of physical properties of biomolecules such as folding, polymer physics of protein and DNA, enzymology and biochemistry, single molecules in the membrane, and single-molecule techniques in living cells.

Cardiovascular Soft Tissue Mechanics

Cardiovascular Soft Tissue Mechanics
Author: Stephen C. Cowin
Publisher: Springer Science & Business Media
Total Pages: 252
Release: 2001
Genre: Mathematics
ISBN: 1402002203

Cowin (New York Center for Biomedical Engineering) and Humphrey (biomedical engineering, Texas A&M U.) present seven papers that discuss current research and future directions. Topics concern tissues within the cardiovascular system (arteries, the heart, and biaxial testing of planar tissues such as heart valves). Themes include an emphasis on data on the underlying microstructure, especially collagen; the consideration of the fact that both arteries and the heart contain muscle and that there is, therefore, a need to quantify both the active and passive response; constitutive relations for active behavior; and the growth and remodeling of cardiovascular tissues. Of interest to cardiovascular and biomechanics soft tissue researchers, and bioengineers. Annotation copyrighted by Book News, Inc., Portland, OR.

Water Stress in Plants

Water Stress in Plants
Author: Ismail M. M. Rahman
Publisher: BoD – Books on Demand
Total Pages: 130
Release: 2016-08-24
Genre: Science
ISBN: 9535126202

Water stress in plants is caused by the water deficit, as induced possibly by drought or high soil salinity. The prime consequence of water stress in plants is the disruption in the agricultural production, resulting in food shortage. The plants, however, try to adapt to the stress conditions using biochemical and physiological interventions. The edited compilation is an attempt to provide new insights into the mechanism and adaptation aspects of water stress in plants through a thoughtful mixture of viewpoints. We hope that the content of the book will be useful for the researchers working with the plant diversity-related environmental aspects and also provide suggestions for the strategists.

Endoplasmic Reticulum Stress in Health and Disease

Endoplasmic Reticulum Stress in Health and Disease
Author: Patrizia Agostinis
Publisher: Springer Science & Business Media
Total Pages: 448
Release: 2012-08-13
Genre: Medical
ISBN: 9400743513

The Endoplasmic Reticulum (ER) is an organelle with extraordinary signaling and homeostatic functions. It is the organelle responsible for protein folding, maturation, quality control and trafficking of proteins destined for the plasma membrane or for secretion into the extracellular environment. Failure, overloading or malfunctioning of any of the signaling or quality control mechanisms occurring in the ER may provoke a stress condition known as ‘ER stress’. Accumulating evidence indicates that ER stress may dramatically perturb interactions between the cell and its environment, and contribute to the development of human diseases, ranging from metabolic diseases and cancer to neurodegenerative diseases, or impact therapeutic outcome. This book primarily focuses on the pathophysiology of ER stress. It introduces the molecular bases of ER stress, the emerging relevance of the ER-mitochondria cross-talk, the signaling pathways engaged and cellular responses to ER stress, including the adaptive Unfolded Protein Response (UPR), autophagy as well as cell death. Next the book addresses the role of ER stress in physiology and in the etiology of relevant pathological conditions, like carcinogenesis and inflammation, neurodegeneration and metabolic disease. The last chapter describes how ER stress pathways can be targeted for therapeutic benefit. Altogether, this book will provide the reader with an exhaustive view of ER stress biology and the latest insights in the role of ER stress in relevant human diseases.