Rethinking the Three R's in Animal Research

Rethinking the Three R's in Animal Research
Author: Jan Lauwereyns
Publisher: Springer
Total Pages: 138
Release: 2018-04-10
Genre: Psychology
ISBN: 3319893009

This work challenges the current reliance on "The Three R's" or Replacement, Reduction and Refinement which direct most animal research in the behavioral sciences. The author argues that these principles that were developed in the 1950's to guide the use of animals in research studies are outdated. He suggests that the notions of refinement and reduction are often ill-defined and can be useful only in cases where replacement is impossible.

Animal Experimentation: Working Towards a Paradigm Change

Animal Experimentation: Working Towards a Paradigm Change
Author: Kathrin Herrmann
Publisher: BRILL
Total Pages: 749
Release: 2019-04-30
Genre: Philosophy
ISBN: 9004391193

Animal experimentation has been one of the most controversial areas of animal use, mainly due to the intentional harms inflicted upon animals for the sake of hoped-for benefits in humans. Despite this rationale for continued animal experimentation, shortcomings of this practice have become increasingly more apparent and well-documented. However, these limitations are not yet widely known or appreciated, and there is a danger that they may simply be ignored. The 51 experts who have contributed to Animal Experimentation: Working Towards a Paradigm Change critically review current animal use in science, present new and innovative non-animal approaches to address urgent scientific questions, and offer a roadmap towards an animal-free world of science.

Rethinking the American Animal Rights Movement

Rethinking the American Animal Rights Movement
Author: Emily Patterson-Kane
Publisher: Routledge
Total Pages: 180
Release: 2022-02-25
Genre: History
ISBN: 1317427068

Along with Civil Rights and Women’s liberation, Animal Rights became one of leading social moments of the twentieth century. This book critically reviews all principal contributions to the American animal rights debate by activists, campaigners, academics, and lawyers, while placing animal rights in context with other related and competing movements. Rethinking the American Animal Rights Movement examines the strategies employed within the movement to advance its goals, which ranged from public advocacy and legal reforms to civil disobedience, vigilantism, anarchism, and even "terrorism." It summarizes key theoretical and legal frameworks that inspired those strategies, as well as the ideological motivations of the movement. It highlights the irreconcilable tension between moral and legal rights verses "humane treatment of animals" as prescribed by advocates of animal welfarism. The book also looks back to the nineteenth century origins of the movement, examining its appeal to a sentimentalist conception of rights standing in marked contrast with twentieth century rights theory. After providing an extensive social history of the twentieth century movement, the book subsequently offers a diagnosis of why it stalled at the turn of millennium in its various efforts to advance the cause of nonhuman animals. This diagnosis emphasizes the often-contradictory goals and strategies adopted by the movement in its different phases and manifestations across three centuries. The book is unique in presenting students, activists, and scholars with a history and critical discussion of its accomplishments, failures, and ongoing complexities faced by the American animal rights movement.

A History of the Development of Alternatives to Animals in Research and Testing

A History of the Development of Alternatives to Animals in Research and Testing
Author: John Parascandola
Publisher: Purdue University Press
Total Pages: 151
Release: 2024-07-15
Genre: Nature
ISBN: 1612499643

Growing public interest in animal welfare issues in recent decades has prompted increased attention to the efforts to develop alternative, nonanimal methods for use in biomedical research and product testing. In A History of the Development of Alternatives to Animals in Research and Testing, the first book-length study of the subject, John Parascandola traces the history of the concept of alternatives to the use of animals in research and testing in Britain and the United States from its beginnings until it had become firmly established in the scientific and animal protection communities by the end of the 1980s. This account of the history of alternatives is set within the context of developments within science, animal welfare, and politics. The book covers the key role played by animal welfare advocates in promoting alternatives, the initial resistance to alternatives on the part of many in the scientific community, the opportunity provided by alternatives for compromise and cooperation between these two groups, and the dominance of the “Three Rs”—reduction, refinement, and replacement.

Principles of Research Methodology and Ethics in Pharmaceutical Sciences

Principles of Research Methodology and Ethics in Pharmaceutical Sciences
Author: Vikas Anand Saharan
Publisher: CRC Press
Total Pages: 519
Release: 2024-08-30
Genre: Medical
ISBN: 1040101658

Pharmaceutical researchers are constantly looking for drug products, drug delivery systems and devices for improving the health of society. A scientific and systematic search for new knowledge requires a thorough understanding of research methods and hypothesis design. This volume presents pharmaceutical research through theoretical concepts, methodologies and ethical issues. It fulfils publication ethics course work requirements for students. Chapters have been designed to cater for the curriculum requirements of universities globally. This serves as a guide on how to apply concepts in designing experiments and transforming laboratory research into actual practice. Features: · Complete coverage of research methodology courses for graduate and postgraduate students globally. · Step-by-step assistance in writing technical reports, projects, protocols, theses and dissertations. · Experimental designing in pharmaceutical formulation development and preclinical research designs. · Ethics in using animals in preclinical research and humans in clinical research. · Publication ethics, best practices and guidelines for ensuring ethical writing. · Hypothetical and real-world case studies on ethical issues and measures for prevention and control.

Towards a New 3Rs Era in Experimental Research

Towards a New 3Rs Era in Experimental Research
Author: Christopher R. Cederroth
Publisher: Frontiers Media SA
Total Pages: 478
Release: 2024-04-29
Genre: Medical
ISBN: 2832548342

With the persisting need of animal experimentation for fundamental and applied research, the relevance and importance of the 3Rs Principle cannot be ignored. The 3Rs Principle was put forward over 50 years ago, providing an essential framework for more humane animal experimentation in research. In this half-century the research landscape within which this principle is applied has dramatically changed and evolved, with ever more emerging venues to explore for 3Rs advancement and implementation.

Applied Ethics in Animal Research

Applied Ethics in Animal Research
Author: John P. Gluck
Publisher: Purdue University Press
Total Pages: 216
Release: 2002
Genre: Medical
ISBN: 9781557531360

This volume is a collection of chapters all contributed by individuals who have presented their ideas at conferences and who take moderate stands with the use of animals in research. Specifically the chapters bear of the issues of: notions of the moral standings of animals, history of the methods of argumentation, knowledge of the animal mind, nature and value of regulatory structures, how respect for animals can be converted from theory to action in the laboratory. The chapters have been tempered by open discussion with individuals with different opinions and not audiences of true believers. It is the hope of all, that careful consideration of the positions in these chapters will leave reader with a deepened understanding--not necessarily a hardened position.