Regulation Of Synthetic Biology
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| Author | : Alison McLennan |
| Publisher | : Edward Elgar Publishing |
| Total Pages | : 283 |
| Release | : 2018-04-27 |
| Genre | : Business & Economics |
| ISBN | : 178536944X |
This book explores the interplay between regulation and emerging technologies in the context of synthetic biology, a developing field that promises great benefits, and has already yielded fuels and medicines made with designer micro-organisms. For all its promise, however, it also poses various risks. Investigating the distinctiveness of synthetic biology and the regulatory issues that arise, Alison McLennan questions whether synthetic biology can be regulated within existing structures or whether new mechanisms are needed.
| Author | : Institute of Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 570 |
| Release | : 2011-12-30 |
| Genre | : Science |
| ISBN | : 0309219396 |
Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.
| Author | : OECD |
| Publisher | : OECD Publishing |
| Total Pages | : 170 |
| Release | : 2014-06-04 |
| Genre | : |
| ISBN | : 9264208429 |
This book examines policy issues in synthetic biology including R&D funding, company investment, PPP arrangements and innovative financing, infrastructure requirements, education and training, intellectual property (IP), regulation, and public engagement.
| Author | : National Academies of Sciences, Engineering, and Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 189 |
| Release | : 2019-01-05 |
| Genre | : Technology & Engineering |
| ISBN | : 0309465184 |
Scientific advances over the past several decades have accelerated the ability to engineer existing organisms and to potentially create novel ones not found in nature. Synthetic biology, which collectively refers to concepts, approaches, and tools that enable the modification or creation of biological organisms, is being pursued overwhelmingly for beneficial purposes ranging from reducing the burden of disease to improving agricultural yields to remediating pollution. Although the contributions synthetic biology can make in these and other areas hold great promise, it is also possible to imagine malicious uses that could threaten U.S. citizens and military personnel. Making informed decisions about how to address such concerns requires a realistic assessment of the capabilities that could be misused. Biodefense in the Age of Synthetic Biology explores and envisions potential misuses of synthetic biology. This report develops a framework to guide an assessment of the security concerns related to advances in synthetic biology, assesses the levels of concern warranted for such advances, and identifies options that could help mitigate those concerns.
| Author | : Vijai Singh |
| Publisher | : Springer Nature |
| Total Pages | : 349 |
| Release | : 2020-04-13 |
| Genre | : Science |
| ISBN | : 9811500819 |
This book addresses the design of emerging conceptual tools, technologies and systems including novel synthetic parts, devices, circuits, oscillators, biological gates, and small regulatory RNAs (riboregulators and riboswitches), which serve as versatile control elements for regulating gene expression. Synthetic biology, a rapidly growing field that involves the application of engineering principles in biology, is now being used to develop novel systems for a wide range of applications including diagnostics, cell reprogramming, therapeutics, enzymes, vaccines, biomaterials, biofuels, fine chemicals and many more. The book subsequently summarizes recent developments in technologies for assembling synthetic genomes, minimal genomes, synthetic biology toolboxes, CRISPR-Cas systems, cell-free protein synthesis systems and microfluidics. Accordingly, it offers a valuable resource not only for beginners in synthetic biology, but also for researchers, students, scientists, clinicians, stakeholders and policymakers interested in the potential held by synthetic biology.
| Author | : Vikram Singh |
| Publisher | : Springer |
| Total Pages | : 383 |
| Release | : 2014-12-15 |
| Genre | : Science |
| ISBN | : 9401795142 |
This textbook has been conceptualized to provide a detailed description of the various aspects of Systems and Synthetic Biology, keeping the requirements of M.Sc. and Ph.D. students in mind. Also, it is hoped that this book will mentor young scientists who are willing to contribute to this area but do not know from where to begin. The book has been divided into two sections. The first section will deal with systems biology – in terms of the foundational understanding, highlighting issues in biological complexity, methods of analysis and various aspects of modelling. The second section deals with the engineering concepts, design strategies of the biological systems ranging from simple DNA/RNA fragments, switches and oscillators, molecular pathways to a complete synthetic cell will be described. Finally, the book will offer expert opinions in legal, safety, security and social issues to present a well-balanced information both for students and scientists.
| Author | : Jian Li |
| Publisher | : Frontiers Media SA |
| Total Pages | : 205 |
| Release | : 2022-01-13 |
| Genre | : Science |
| ISBN | : 2889740803 |
| Author | : Lewis D. Solomon |
| Publisher | : Routledge |
| Total Pages | : 174 |
| Release | : 2017-09-28 |
| Genre | : |
| ISBN | : 9781138515178 |
Cover -- Half Title -- Title Page -- Copyright Page -- Dedication -- Table of Contents -- Introduction -- Part I: Background -- 2. The Beginnings of Earthly Life -- 3. The Design for Life -- Part II: Reading Life -- 4. Reading the Genetic Code: Sequencing the Human Genome -- Part III: The Quest to Write Life -- 5. Organizational Structure and Funding of Nonprofit Entities -- 6. Research Progress -- 7. Commercialization Efforts: Synthetic Genomics, Inc. -- 8. Competitors in the Race to Commercialize Biofuels and Chemicals -- 9. Conclusion: Policy Implications of Synthetic Biology Research and Commercialization -- Index
| Author | : National Research Council |
| Publisher | : National Academies Press |
| Total Pages | : 254 |
| Release | : 2004-07-08 |
| Genre | : Science |
| ISBN | : 0309166152 |
Assists policymakers in evaluating the appropriate scientific methods for detecting unintended changes in food and assessing the potential for adverse health effects from genetically modified products. In this book, the committee recommended that greater scrutiny should be given to foods containing new compounds or unusual amounts of naturally occurring substances, regardless of the method used to create them. The book offers a framework to guide federal agencies in selecting the route of safety assessment. It identifies and recommends several pre- and post-market approaches to guide the assessment of unintended compositional changes that could result from genetically modified foods and research avenues to fill the knowledge gaps.
| Author | : Rajesh K. Gaur |
| Publisher | : CRC Press |
| Total Pages | : 440 |
| Release | : 2009-04-27 |
| Genre | : Science |
| ISBN | : 1420008706 |
New Findings Revolutionize Concepts of Gene FunctionEndogenous small RNAs have been found in various organisms, including humans, mice, flies, worms, fungi, and bacteria. Furthermore, it's been shown that microRNAs acting as cellular rheostats have the ability to modulate gene expression. In higher eukaryotes, microRNAs may regulate as much as 50 p
