Translational Regenerative Medicine

Translational Regenerative Medicine
Author: Anthony Atala
Publisher: Academic Press
Total Pages: 607
Release: 2014-12-01
Genre: Medical
ISBN: 0124104576

Translational Regenerative Medicine is a reference book that outlines the life cycle for effective implementation of discoveries in the dynamic field of regenerative medicine. By addressing science, technology, development, regulatory, manufacturing, intellectual property, investment, financial, and clinical aspects of the field, this work takes a holistic look at the translation of science and disseminates knowledge for practical use of regenerative medicine tools, therapeutics, and diagnostics. Incorporating contributions from leaders in the fields of translational science across academia, industry, and government, this book establishes a more fluid transition for rapid translation of research to enhance human health and well-being. - Provides formulaic coverage of the landscape, process development, manufacturing, challenges, evaluation, and regulatory aspects of the most promising regenerative medicine clinical applications - Covers clinical aspects of regenerative medicine related to skin, cartilage, tendons, ligaments, joints, bone, fat, muscle, vascular system, hematopoietic /immune system, peripheral nerve, central nervous system, endocrine system, ophthalmic system, auditory system, oral system, respiratory system, cardiac system, renal system, hepatic system, gastrointestinal system, genitourinary system - Identifies effective, proven tools and metrics to identify and pursue clinical and commercial regenerative medicine

Regenerative Medicine in the Genitourinary System

Regenerative Medicine in the Genitourinary System
Author: Farshid Sefat
Publisher: Elsevier
Total Pages: 352
Release: 2024-04-19
Genre: Science
ISBN: 0443158355

Regenerative Medicine in the Genitourinary System gives the reader a comprehensive overview of tissue engineering used to treat genitourinary disorders and infertility, also providing a great learning platform for researchers in different fields such as cell biology, pharmaceutics, clinicians, chemists, material scientists, and more. The book covers the latest innovations on the subject, but also acts as a resource for tissue engineering applications and regenerative medicine. Over the last several decades, tissue engineering has continued to make considerable advancements in therapeutic and clinical strategies that address male/female urological or genitourinary diseases. Although several articles have been published on this topic, there are very few book chapters and no single book currently available dedicated to this topic. - Provides extensive principles of tissue engineering in urinary and reproductive systems - Presents excellent examples of tissue engineering and regenerative medicine (translational medicine) to tackle diseases and disorders related to the urinogenital system - Includes chapters covering erectile disfunction, as well as tissue engineering strategies to treat male and female infertility

Principles of Tissue Engineering

Principles of Tissue Engineering
Author: Robert Lanza
Publisher: Elsevier
Total Pages: 1039
Release: 2000-05-16
Genre: Science
ISBN: 008053967X

The opportunity that tissue engineering provides for medicine is extraordinary. In the United States alone, over half-a-trillion dollars are spent each year to care for patients who suffer from tissue loss or dysfunction. Although numerous books and reviews have been written on tissue engineering, none has been as comprehensive in its defining of the field. Principles of Tissue Engineering combines in one volume the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation of applications of tissue engineering to diseases affecting specific organ systems. The first edition of the book, published in 1997, is the definite reference in the field. Since that time, however, the discipline has grown tremendously, and few experts would have been able to predict the explosion in our knowledge of gene expression, cell growth and differentiation, the variety of stem cells, new polymers and materials that are now available, or even the successful introduction of the first tissue-engineered products into the marketplace. There was a need for a new edition, and this need has been met with a product that defines and captures the sense of excitement, understanding and anticipation that has followed from the evolution of this fascinating and important field.Key Features* Provides vast, detailed analysis of research on all of the major systems of the human body, e.g., skin, muscle, cardiovascular, hematopoietic, and nerves* Essential to anyone working in the field* Educates and directs both the novice and advanced researcher* Provides vast, detailed analysis of research with all of the major systems of the human body, e.g. skin, muscle, cardiovascular, hematopoietic, and nerves* Has new chapters written by leaders in the latest areas of research, such as fetal tissue engineering and the universal cell* Considered the definitive reference in the field* List of contributors reads like a "who's who" of tissue engineering, and includes Robert Langer, Joseph Vacanti, Charles Vacanti, Robert Nerem, A. Hari Reddi, Gail Naughton, George Whitesides, Doug Lauffenburger, and Eugene Bell, among others

Principles of Regenerative Medicine

Principles of Regenerative Medicine
Author: Anthony Atala
Publisher: Academic Press
Total Pages: 1203
Release: 2010-12-16
Genre: Science
ISBN: 0123814235

Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. - Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology - The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine - New discoveries from leading researchers on restoration of diseased tissues and organs

Stem Cell and Tissue Engineering

Stem Cell and Tissue Engineering
Author: Song Li
Publisher: World Scientific
Total Pages: 473
Release: 2011
Genre: Science
ISBN: 9814317055

Tissue engineering integrates knowledge and tools from biological sciences and engineering for tissue regeneration. A challenge for tissue engineering is to identify appropriate cell sources. The recent advancement of stem cell biology provides enormous opportunities to engineer stem cells for tissue engineering. The impact of stem cell technology on tissue engineering will be revolutionary. This book covers state-of-the-art knowledge on the potential of stem cells for the regeneration of a wide range of tissues and organs and the technologies for studying and engineering stem cells. It serves as a valuable reference book for researchers and students.

Western Biomedicine and Eastern Therapeutics

Western Biomedicine and Eastern Therapeutics
Author: Sun-Chong Wang
Publisher: World Scientific
Total Pages: 379
Release: 2013
Genre: Medical
ISBN: 9814412880

Modern Western Medicine (MWM) and Ayurveda/Traditional Chinese Medicine (TCM) can be considered two extreme paradigms to complex systems. The microscopic and reductionist approach of the West prevails in acute and single-gene conditions such as infection and Mendelian disorders. The macroscopic and holistic approach of the East potentially fares well at chronic and complex conditions such as obesity and ageing. The book serves three purposes: 1) to help MWM, Ayurveda and TCM professionals get acquainted with one another; 2) to help identify common grounds for MWM, Ayurveda and TCM, rather than blindly westernizing eastern medicines or vice versa; and 3) to help translate the complementarity of MWM and Ayurveda/TCM toward an integrative multi-component healthcare. To this end, we introduce theories and tenets of the three medicines. We use bioenergetics to reconcile West and East as ATP generation, prana and qi are central to MWM, Ayurveda and TCM. We discuss clinical trials of varying experimental rigors for the assessment of the scientific evidence for treatment effectiveness. We present complementary interventions for chronic disorders and ageing. We hold that a federal unity of therapies consisting of MWM, Ayurveda and TCM better serves the wellbeing of humankind.

Adipose-Derived Stem Cells

Adipose-Derived Stem Cells
Author: Jeffrey M. Gimble
Publisher: Humana Press
Total Pages: 474
Release: 2011-08-24
Genre: Science
ISBN: 9781617379611

During the past decade, a wide range of scientific disciplines have adopted the use of adipose-derived stem/stromal cells (ASCs) as an important tool for research and discovery. In Adipose-Derived Stem Cells: Methods and Protocols, experts from the field, including members of the esteemed International Federation of Adipose Therapeutics and Science (IFATS), provide defined and established protocols in order to further codify the utilization of these powerful and accessible cells. With chapters organized around approaches spanning the discovery, pre-clinical, and clinical processes, much of the emphasis is placed on human ASC, while additional techniques involving small and large animal species are included. As a volume in the highly successful Methods in Molecular BiologyTM series, the detailed contributions include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Adipose-Derived Stem Cells: Methods and Protocols serves as a vital reference text for experienced researchers as well as new students on the path to further exploring the incredible potential of ASCs.

Stem Cells in Urology

Stem Cells in Urology
Author: Seyed Mohammad Kazem Aghamir
Publisher: Springer Nature
Total Pages: 122
Release: 2020-05-11
Genre: Science
ISBN: 3030414760

This contributed volume emphasizes the potential of stem cells to be pertained in the urology field and attempts to disclose the history of the field up to the latest advances to date. It gathers the majority of papers that advocate utilizing stem cells as the best option for treating, diagnosing, and managing diseases related to urological system. This book covers a broad spectrum of issues, including mesenchymal stem cells, cancer stem cells, organoids, regenerative medicine, erectile dysfunction, bladder dysfunction, and kidney transplant. From several decades ago, as characteristic features of stem cells have been explored, it has attracted a great amount of interests. In view of their multiple capacity of differentiating into various lineages, many studies were conducted to assess their beneficial potential. Despite considerable progress into applying stem cells in animal models, for translating into clinical practices there are several obstacles to be resolved. However, few clinical studies have been performed in each field and outcomes were delightful. There is an ongoing hope for stem cells to someday, be the mainstream treatments of urological diseases, although stem cells treatments already exist they are not well-known. Indeed, this book is essential for anyone who is working with the purpose of employing stem cells to treat the urological diseases and discusses at length the latest advances as well as their limitations.

Biomaterials and Tissue Engineering in Urology

Biomaterials and Tissue Engineering in Urology
Author: John Denstedt
Publisher: Elsevier
Total Pages: 593
Release: 2009-04-29
Genre: Technology & Engineering
ISBN: 1845696379

Urology is the branch of medicine dealing with disorders or diseases of the male genitor-urinary tract and the female urinary tract. This important book summarises the wealth of recent research on the use of biomaterials and tissue engineering to treat urological disorders.Part one reviews the fundamentals with chapters on such topics as biofilms and encrustation formation. Part two then discusses recent advances in biomaterials and design of urological devices such as metal ureteral stents, self-lubricating catheter materials and penile implants. Chapters in Part three address urological tissue engineering with coverage of themes such as artificial and natural biomaterials, nano-technology and placental stem cells for tissue engineering the regeneration of urological tissue and organs.With its eminent editors and international team of contributors, Biomaterials and tissue engineering in urology is an invaluable resource to researchers of urological biomaterials, devices and regenerative medicine in both industry and academia, as well as an important reference for medical practitioners. - Provides a comprehensive review of biomaterials and tissue engineering in urology - Explores the fundamentals of urology, focusing on biofilms and encrustation and formation - Discusses recent advances in biomaterials and the design of urological devices, catheters and stents

Foundations of Regenerative Medicine

Foundations of Regenerative Medicine
Author: Anthony Atala
Publisher: Academic Press
Total Pages: 823
Release: 2009-09-04
Genre: Science
ISBN: 0123785626

The interdisciplinary field of regenerative medicine holds the promise of repairing and replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. Derived from the fields of tissue engineering, cell and developmental biology, biomaterials science, nanotechnology, physics, chemistry, physiology, molecular biology, biochemistry, bioengineering, and surgery, regenerative medicine is one of the most influential topics of biological research today.Derived from the successful Principles of Regenerative Medicine, this volume brings together the latest information on the advances in technology and medicine and the replacement of tissues and organs damaged by disease. Chapters focus on the fundamental principles of regenerative therapies that have crossover with a broad range of disciplines. From the molecular basis to therapeutic applications, this volume is an essential source for students, researchers, and technicians in tissue engineering, stem cells, nuclear transfer (therapeutic cloning), cell, tissue, and organ transplantation, nanotechnology, bioengineering, and medicine to gain a comprehensive understanding of the nature and prospects for this important field. - Highlights the fundamentals of regenerative medicine to relate to a variety of related science and technology fields - Introductory chapter directly addresses why regenerative medicine is important to a variety of researchers by providing practical examples and references to primary literature - Includes new discoveries from leading researchers on restoration of diseased tissues and organs