Stem Cells and the Future of Regenerative Medicine

Stem Cells and the Future of Regenerative Medicine
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 112
Release: 2002-01-25
Genre: Science
ISBN: 0309170427

Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.

Nanotechnology in Regenerative Medicine and Drug Delivery Therapy

Nanotechnology in Regenerative Medicine and Drug Delivery Therapy
Author: Haiyan Xu
Publisher: Springer Nature
Total Pages: 490
Release: 2020-07-21
Genre: Medical
ISBN: 9811553866

The book focuses on the application of nanotechnologies in scaffold-guided tissue regeneration and in drug delivery systems for use in immunotherapy and overcoming drug resistance in cancer treatment. It covers a variety of topics, including nanomaterials for immunomodulation and immnunotherapy; molecular studies on self-assembly for peptides and DNA and related applications in tumor diagnosis and therapeutics and against human pathogenic bacteria; magnetic and conductive scaffolds for guiding tissue regeneration; multiple functions of magnetic nanoparticles in drug delivery and regenerative medicine; and re-purposing of traditional medicine in nano-formulations. In addition, it discusses common effects of nanomaterials, including reactive oxygen species and protein corona. Providing valuable insights and the presenting the latest research advances, the book allows readers to gain a systematic understanding of the topic.

Regenerative Medicine in China

Regenerative Medicine in China
Author: Xiaobing Fu
Publisher: Springer Nature
Total Pages: 485
Release: 2021-08-01
Genre: Medical
ISBN: 9811611823

This book includes major issues in wound tissue repair and regeneration in 14 chapters. The topics start from cytological basis, molecular and genetic basis, skin development, to the tissue repair, visceral injury and tissue engineering. In the second part, it introduces Chinese researchers’ contribution in wound repair and regeneration. Specially, it has 3 chapters discussing new technologies in tissue repair and regeneration, and 1 chapter in Traditional Chinese Medicine.

Stem Cell Therapies

Stem Cell Therapies
Author: Adam C. Berger
Publisher: National Academy Press
Total Pages: 108
Release: 2014-06-18
Genre: Medical
ISBN: 9780309303002

Stem cells offer tremendous promise for advancing health and medicine. Whether being used to replace damaged cells and organs or else by supporting the body's intrinsic repair mechanisms, stem cells hold the potential to treat such debilitating conditions as Parkinson's disease, diabetes, and spinal cord injury. Clinical trials of stem cell treatments are under way in countries around the world, but the evidence base to support the medical use of stem cells remains limited. Despite this paucity of clinical evidence, consumer demand for treatments using stem cells has risen, driven in part by a lack of available treatment options for debilitating diseases as well as direct-to-consumer advertising and public portrayals of stem cell-based treatments. Clinics that offer stem cell therapies for a wide range of diseases and conditions have been established throughout the world, both in newly industrialized countries such as China, India, and Mexico and in developed countries such as the United States and various European nations. Though these therapies are often promoted as being established and effective, they generally have not received stringent regulatory oversight and have not been tested with rigorous trials designed to determine their safety and likely benefits. In the absence of substantiated claims, the potential for harm to patients - as well as to the field of stem cell research in general - may outweigh the potential benefits. To explore these issues, the Institute of Medicine, the National Academy of Sciences, and the International Society for Stem Cell Research held a workshop in November 2013. "Stem Cell Therapies" summarizes the workshop. Researchers, clinicians, patients, policy makers, and others from North America, Europe, and Asia met to examine the global pattern of treatments and products being offered, the range of patient experiences, and options to maximize the well-being of patients, either by protecting them from treatments that are dangerous or ineffective or by steering them toward treatments that are effective. This report discusses the current environment in which patients are receiving unregulated stem cell offerings, focusing on the treatments being offered and their risks and benefits. The report considers the evidence base for clinical application of stem cell technologies and ways to assure the quality of stem cell offerings.

Perinatal Stem Cells

Perinatal Stem Cells
Author: Anthony Atala
Publisher: Academic Press
Total Pages: 438
Release: 2018-06-14
Genre: Medical
ISBN: 0128120630

Perinatal Stem Cells provides researchers and clinicians with a comprehensive description of the current clinical and pre-clinical applications of stem cells derived from perinatal sources, such as amniotic fluid, placenta and placental membranes, the umbilical cord and Wharton’s jelly. It's compiled by leading experts in the field, offering readers detailed insights into sources of perinatal stem cells and their potential for disease treatment. Therapeutic applications of perinatal stem cells include the treatment of in utero and pregnancy related diseases, cardiac disease, liver disease, pulmonary disease, inflammatory diseases, for hematopoietic regeneration, and for neural protection after stroke or traumatic brain injury. In addition, the rapid advance in clinical translation and commercialization of perinatal stem cell therapies is highlighted in a section on Clinical and Industry Perspective which provides insight into the new opportunities and challenges involved in this novel and exciting industry. Explores current clinical and pre-clinical application of stem cells derived from perinatal sources Offers detailed insight into sources of perinatal stem cells and their potential for disease treatment Discusses progress in the manufacturing, banking and clinical translation of perinatal stem cells Edited by a world-renowned team to present a complete story of the development and promise of perinatal stem cells

Regenerative Medicine Procedures for Aesthetic Physicians

Regenerative Medicine Procedures for Aesthetic Physicians
Author: Hernán Pinto
Publisher: Springer
Total Pages: 264
Release: 2019-08-02
Genre: Medical
ISBN: 3030154580

This book presents the state-of-art in regenerative procedures currently applied by aesthetic physicians, plastic surgeons and dermatologists. It is divided into two parts, the first of which provides a detailed introduction to aesthetic medicine and the aging process. The second part, in turn, addresses the current status of techniques and technologies with regard to autologous grafts, covering fat transfer, blood grafts, skin grafts and stem cells. The book examines the surgical applications of these grafts, as well as potential side effects and limitations. Therapy combinations and outcomes round out the coverage. Aesthetic physicians, plastic surgeons and dermatologists interested in performing regenerative procedures for aesthetic purposes will find this book to be a valuable guide.

Neurologic Rehabilitation

Neurologic Rehabilitation
Author: Bruce H. Dobkin
Publisher: Oxford University Press, USA
Total Pages: 366
Release: 1996
Genre: Medical
ISBN:

Dobkin (Director, Neurologic Rehabilitation and Research, U. of California Los Angeles School of Medicine) examines clinical disorders that arise during the rehabilitation of diseases of the central and peripheral nervous systems. His findings concentrate on aspects of motor control, muscle plasticity, and cognitive processes as they relate to the rehabilitation teams' role in assessment and practice. He comprehensively discusses specific issues in the areas of stroke, spinal cord injury, traumatic brain injury, Parkinson's Disease, multiple sclerosis, and other neurologic disorders. Annotation copyright by Book News, Inc., Portland, OR

Western Biomedicine and Eastern Therapeutics

Western Biomedicine and Eastern Therapeutics
Author: Sun-Chong Wang
Publisher: World Scientific
Total Pages: 379
Release: 2013
Genre: Medical
ISBN: 9814412880

Modern Western Medicine (MWM) and Ayurveda/Traditional Chinese Medicine (TCM) can be considered two extreme paradigms to complex systems. The microscopic and reductionist approach of the West prevails in acute and single-gene conditions such as infection and Mendelian disorders. The macroscopic and holistic approach of the East potentially fares well at chronic and complex conditions such as obesity and ageing. The book serves three purposes: 1) to help MWM, Ayurveda and TCM professionals get acquainted with one another; 2) to help identify common grounds for MWM, Ayurveda and TCM, rather than blindly westernizing eastern medicines or vice versa; and 3) to help translate the complementarity of MWM and Ayurveda/TCM toward an integrative multi-component healthcare. To this end, we introduce theories and tenets of the three medicines. We use bioenergetics to reconcile West and East as ATP generation, prana and qi are central to MWM, Ayurveda and TCM. We discuss clinical trials of varying experimental rigors for the assessment of the scientific evidence for treatment effectiveness. We present complementary interventions for chronic disorders and ageing. We hold that a federal unity of therapies consisting of MWM, Ayurveda and TCM better serves the wellbeing of humankind.

Tiger of Beijing

Tiger of Beijing
Author: Joy Kong
Publisher:
Total Pages: 304
Release: 2019-10-24
Genre: Biography & Autobiography
ISBN: 9781647139742

Young Joy, who has been experiencing the stifling control of the Chinese government over the lofty ambitions of university students like herself to study abroad, has just realized that the forces amassed against her won't budge a millimeter despite her efforts to work within the system. So Joy initiates a complex series of daring scenarios to beat the legal system at its own game in order to secure her exit visa to the United States. And she does: transforming herself into the Tiger of Beijing. Calculated. Intuitive. Fierce. But before her plane lands in the Land of Opportunity, Joy finds herself faced with another problem that proves to be much more challenging than leaving a Communist country. Psychologically pushed to the brink of ruin in every way imaginable, Joy once again calls forth the Tiger of Beijing from deep within herself. Set against the austere backdrop of the post-Tiananmen Square Incident in Beijing, China, Tiger of Beijing dramatically relays Joy's five-year hero's journey that takes her across the Atlantic and into the heart of San Francisco where she finally experiences the freedom of the human spirit for which she had longed as a young girl.

Biomedical Odysseys

Biomedical Odysseys
Author: Priscilla Song
Publisher: Princeton University Press
Total Pages: 315
Release: 2017-05-16
Genre: Social Science
ISBN: 1400885280

Thousands of people from more than eighty countries have traveled to China since 2001 to undergo fetal cell transplantation. Galvanized by the potential of stem and fetal cells to regenerate damaged neurons and restore lost bodily functions, people grappling with paralysis and neurodegenerative disorders have ignored the warnings of doctors and scientists back home in order to stake their futures on a Chinese experiment. Biomedical Odysseys looks at why and how these individuals have entrusted their lives to Chinese neurosurgeons operating on the forefront of experimental medicine, in a world where technologies and risks move faster than laws can keep pace. Priscilla Song shows how cutting-edge medicine is not just about the latest advances in biomedical science but also encompasses transformations in online patient activism, surgical intervention, and borderline experiments in health care bureaucracy. Bringing together a decade of ethnographic research in hospital wards, laboratories, and online patient discussion forums, Song opens up important theoretical and methodological horizons in the anthropology of science, technology, and medicine. She illuminates how poignant journeys in search of fetal cell cures become tangled in complex webs of digital mediation, the entrepreneurial logics of postsocialist medicine, and fraught debates about the ethics of clinical experimentation. Using innovative methods to track the border-crossing quests of Chinese clinicians and their patients from around the world, Biomedical Odysseys is the first book to map the transnational life of fetal cell therapies.