The Effect of Calorie Restriction and Intermittent Fasting on Health and Disease

The Effect of Calorie Restriction and Intermittent Fasting on Health and Disease
Author: Hae-Young Chung
Publisher: MDPI
Total Pages: 186
Release: 2021-01-29
Genre: Science
ISBN: 3039438379

Recent biochemical studies indicate that calorie restriction (CR) is a widely accepted method for anti-aging intervention. CR and intermittent fasting (IF), which involves reduced calories but proper nutritional intake during specific periods, are interventions that can consistently promote health benefits, delay biological aging, and extend both average and maximal lifespan. Furthermore, CR can modulate age-related diseases such as Alzheimer’s disease, atherosclerosis, diabetes, obesity, cancer, and others. Advances in omics technologies have provided a technical breakthrough that enabled the investigation of DNA, RNA, proteins, and other cellular molecules and their comprehensive interactions in a biological context. Nowadays, it is possible to analyze and integrate biological processes that occur in aging systems at the molecular level using state-of-the-art techniques such as next-generation sequencing (NGS), proteomics, lipidomics, metabolomics, and epigenomics. Omics technology and systems gerontology provide predictive information on CR effects, molecular mechanisms, and pathways underlying the anti-aging actions of CR and IF. This Special Issue, “The effects of calorie restriction and intermittent fasting on health and disease”, focuses on the effects of calorie restriction and intermittent fasting on age-related inflammation, autophagy, metabolism, longevity, mitochondrial function, and age-related diseases.

Revision of the Miocene and Pliocene Equidae of North America

Revision of the Miocene and Pliocene Equidae of North America
Author: James Williams Gidley
Publisher:
Total Pages: 78
Release: 1907
Genre: Equidae
ISBN:

"In the foregoing revision the lines of comparison and study have been confined principally to characters of the teeth and skull, for the reason that by far the greater number of species of horses have been founded on tooth and skull material not associated with other parts of the skeleton. The expeditions of the last few years however are constantly increasing the collections and adding quantities of more complete material, including many specimens in which teeth and bones of the feet are associated. This class of material will greatly aid in working out more fully than has been done the characters of foot development of horses, and should result in throwing added light on the phyletic relations of the extremely varied groups which seem to have reached their culmination, as regards numbers of genera and species, in the Miocene period. The principal results attained by this study are, first, a better understanding and interpretation of the principal characters shown in the numerous and varied types representing the American Miocene horses; second, the reestablishment and better definition of several of the genera and species proposed by Leidy, the validity of which was questioned by Cope; and third, a reclassification of the entire family of the Equiidae. As at present understood, the fact seems to be fairly well established that there is a considerable phyletic hiatus between the groups of the Equidae as above subdivided, which are as yet not bridged over by intermediate forms. Such a hiatus seems especially marked between the Anchitheriinae and the Protohippinae, while these groups greatly overlap each other in time. So far as indicated by any known species the Anchitheriinae could not well have stood in direct ancestral line to the latter group or to the Equiinae. There seems also to be almost as decided a gap between the Anchitheriinae and the known species of the older group, the Hyracotheriinae. The Equiinae may well have been derived from some species of the Protohippus division of the Protohippinae"--Page 933-934

The MD Anderson Manual of Medical Oncology

The MD Anderson Manual of Medical Oncology
Author: Hagop M. Kantarjian
Publisher: McGraw-Hill Prof Med/Tech
Total Pages: 1172
Release: 2006-03-22
Genre: Medical
ISBN: 9780071414999

A concise, up-to-date clinician's guide to cancer management -- from the leaders in the field A Doody's Core Title! The MD Anderson Cancer Center is ranked as the world's leading institution in cancer medicine. With publication of the MD Anderson Manual of Medical Oncology, the editorial board of this prestigious institution makes available for the first time a resource that meets the needs of clinicians for an authoritative, accessible guide to the medical management of patients with cancer and its complications. Straight-to-the-point, state-of-the-art strategies for cancer management Gives physicians a current, coherent approach to each disease and situation -- imbued with the clinical expertise and teaching authority of world class oncology researchers/practitioners Consistently formatted for a unified patient management strategy Packed with time-saving features, including “The M.D. Anderson Work-Up Box” and “The M.D. Anderson Preferred Treatment Box” Examines special issues in breast cancer management…current treatment strategies for infection in the neutropenic patient and management of fungal and viral infections in cancer patients… basic concepts and controversies related to allogeneic marrow transplantation…more Provides guidelines for oncologic emergencies and palliative care Outlines procedures for symptom control in long-term survival… long-term follow-up in pediatric and adult patients…and rehabilitation

Fundamental Biomaterials: Metals

Fundamental Biomaterials: Metals
Author: Preetha Balakrishnan
Publisher: Woodhead Publishing
Total Pages: 466
Release: 2018-07-19
Genre: Technology & Engineering
ISBN: 0081022069

Fundamental Biomaterials: Metals provides current information on the development of metals and their conversion from base materials to medical devices. Chapters analyze the properties of metals and discuss a range of biomedical applications, with a focus on orthopedics. While the book will be of great use to researchers and professionals in the development stages of design for more appropriate target materials, it will also help medical researchers understand, and more effectively communicate, the requirements for a specific application. With the recent introduction of a number of interdisciplinary bio-related undergraduate and graduate programs, this book will be an appropriate reference volume for students. It represents the second volume in a three volume set, each of which reviews the most important and commonly used classes of biomaterials, providing comprehensive information on materials properties, behavior, biocompatibility and applications. - Provides current information on metals and their conversion from base materials to medical devices - Includes analyses of types of metals, discussion of a range of biomedical applications, and essential information on corrosion, degradation and wear and lifetime prediction of metal biomaterials - Explores both theoretical and practical aspects of metals in biomaterials

D20 Modern Roleplaying Game

D20 Modern Roleplaying Game
Author: Jeff Grubb
Publisher:
Total Pages: 0
Release: 2002
Genre: Fantasy games
ISBN: 9780786928361

This book is designed to be the complete rulebook for all modern roleplaying games using the d20 settings. Thematically aligned with the highly popular heroic fantasy and horror genres, this volume will build on the strength of the growing d20 System while attracting new players.