Disease Control Priorities, Third Edition (Volume 5)

Disease Control Priorities, Third Edition (Volume 5)
Author: Dorairaj Prabhakaran
Publisher: World Bank Publications
Total Pages: 948
Release: 2017-11-17
Genre: Medical
ISBN: 1464805202

Cardiovascular, respiratory, and related conditions cause more than 40 percent of all deaths globally, and their substantial burden is rising, particularly in low- and middle-income countries (LMICs). Their burden extends well beyond health effects to include significant economic and societal consequences. Most of these conditions are related, share risk factors, and have common control measures at the clinical, population, and policy levels. Lives can be extended and improved when these diseases are prevented, detected, and managed. This volume summarizes current knowledge and presents evidence-based interventions that are effective, cost-effective, and scalable in LMICs.

Ischemic Stroke

Ischemic Stroke
Author: Chung Y. Hsu
Publisher: Karger Medical and Scientific Publishers
Total Pages: 176
Release: 1998
Genre: Medical
ISBN: 3805565607

'... Provides an admirable review of current knowledge regarding experimental stroke research, and outlines the problems and some solutions in the clinical application of such knowledge.'

Stroke Genetics

Stroke Genetics
Author: Hugh S. Markus
Publisher: Oxford Medical Publications
Total Pages: 362
Release: 2003
Genre: Medical
ISBN: 0198515863

Stroke is a major cause of death and the major cause of adult neurological disability in most of the world. Despite its importance on a population basis, research into the genetics of stroke has lagged behind that of many other disorders. However, the situation is now changing. Anincreasing number of single gene disorders causing stroke are being described, and there is growing evidence that polygenic factors are important in the risk of apparently "sporadic" stroke.Stroke Genetics provides an up-to-date review of the area, suitable for clinicians treating stroke patients, and both clinical and non-clinical researchers in the field of cerebrovascular disease. The full range of monogenic stroke disorders causing cerebrovascular disease, including ischaemicstroke, intracerebral haemorrhage, aneurysms and arteriovenous malformations, are covered. For each, clinical features, diagnosis, and genetics are described. Increasing evidence suggest that genetic factors are also important for the much more common multifactorial stroke; this evidence isreviewed along with the results of genetic studies in this area. Optimal and novel strategies for investigating multifactorial stroke, including the use of intermediate phenotypes such as intima-media thickness and MRI detected small vessel disease are reviewed. The book concludes by describing apractical approach to investigating patients with stroke for underlying genetic disorders. Also included is a list of useful websites.

Cellular and Molecular Approaches to Regeneration and Repair

Cellular and Molecular Approaches to Regeneration and Repair
Author: Paul A. Lapchak
Publisher: Springer
Total Pages: 532
Release: 2017-11-04
Genre: Medical
ISBN: 3319666797

This book discusses recent advances in the field of translational stroke research. The editors have designed the book to provide new insight into the importance of regeneration and repair mechanisms for stroke victims. The editors have brought together a talented group of international stroke researchers and clinicians to contribute to this volume, which is written for students, researchers and physicians in biotechnology, neurosciences, neurology, neuroradiology and neurosurgery. Throughout the world, stroke is still a leading cause of mortality and morbidity; there are 152,000 strokes in the United Kingdom, 62,000 in Canada, and approximately 15 million people worldwide. Large communities of stroke survivors are eagerly awaiting scientific advances in translational stroke research related to regeneration and recovery of function that would offer new therapeutics for rehabilitation and regeneration utilizing novel stem cell and molecular-based approaches. This volume will allow the reader to undersnd the future of stroke treatment from its inception in the laboratory through to clinical trial design. The reader will learn about the recent advances made in these areas related to basic and applied stroke research and their translational potential. Dr. Paul A. Lapchak is Professor of Neurology and Director of Translational Research in the Departments of Neurology & Neurosurgery at Cedars-Sinai Medical Center in Los Angeles CA, USA. Dr. Lapchak is an internationally recognized expert conducting translational drug development research for ischemic and hemorrhagic stroke. Dr. John H. Zhang is Professor of Anesthesiology, Neurosurgery, Neurology, and Physiology, and Director, Center for Neuroscience Research at Loma Linda University School of Medicine, Loma Linda, CA, USA. Dr. Zhang is an internationally recognized expert working on drug development for hemorrhagic stroke.

New Trends in Diagnosis and Management of Stroke

New Trends in Diagnosis and Management of Stroke
Author: Klaus Poeck
Publisher: Springer
Total Pages: 166
Release: 1987
Genre: Medical
ISBN:

It might appear bold to publish the proceedings of yet another sym posium on the diagnosis and management of stroke. However, I hope in selecting topics to reflect 'new trends' and in inviting speakers to discuss these trends and the related concepts and results, that we have been suc cessful in attaining a high level of scholarship as well as in appealing to a wide readership. The central issues here derive from a new typology of strokes that should replace the obsolete distinction based on purely temporal param eters so aptly criticized by Caplan. A classification of strokes on the basis of pathogenesis requires a synopsis of information gained from history, neurological and cardiovascular findings, ultrasound studies (ex tracranial as well as transcranial), correctly timed CT scan investigation and, if necessary, from selective angiography. Only the recognition of the role of pathogenetic events for a patient permits the application of a ra tional therapy regimen.

Acute Ischemic Stroke

Acute Ischemic Stroke
Author: R. Gilberto González
Publisher: Springer Science & Business Media
Total Pages: 299
Release: 2010-10-05
Genre: Medical
ISBN: 3642127517

This updated second edition of Acute Ischemic Stroke: Imaging and Intervention provides a comprehensive account of the state of the art in the diagnosis and treatment of acute ischemic stroke. The basic format of the first edition has been retained, with sections on fundamentals such as pathophysiology and causes, imaging techniques and interventions. However, each chapter has been revised to reflect the important recent progress in advanced neuroimaging and the use of interventional tools. In addition, a new chapter is included on the classification instruments for ischemic stroke and their use in predicting outcomes and therapeutic triage. All of the authors are internationally recognized experts and members of the interdisciplinary stroke team at the Massachusetts General Hospital and Harvard Medical School. The text is supported by numerous informative illustrations, and ease of reference is ensured through the inclusion of suitable tables. This book will serve as a unique source of up-to-date information for neurologists, emergency physicians, radiologists and other health care providers who care for the patient with acute ischemic stroke.

Translational Stroke Research

Translational Stroke Research
Author: Paul A. Lapchak
Publisher: Springer Science & Business Media
Total Pages: 926
Release: 2012-03-22
Genre: Medical
ISBN: 1441995307

This volume sets a basis for effective translational research. Authored by experts in the field of translational stroke research, each chapter specifically addresses one or more components of preclinical stroke research. The emphasis is placed on target identification and drug development using state-of-the-art in vitro and in vivo assays, in combination with in vitro toxicology assays, AMDE and clinical design.