Recent progress in Melioidosis and Glanders

Recent progress in Melioidosis and Glanders
Author: Alfredo G. Torres
Publisher: Frontiers E-books
Total Pages: 105
Release:
Genre:
ISBN: 2889190811

Burkholderia pseudomallei and B. mallei, causes melioidosis and glanders, respectively, which are two endemic infectious diseases in many parts of the world. The recent reports of glanders outbreaks in horses in Pakistan and Bahrain and the increasing incidence of human melioidosis in Thailand and other tropical regions have resulted in increased research efforts to prevent these diseases. Moreover, both B. mallei and B. pseudomallei exhibit an intriguing intracellular life cycle including the induction of actin tail formation and cell fusion and thereby have developed as model organisms in infection biology. This Research Topic summarizes recent progress to understand these pathogens at the molecular level, with emphasis in their virulence traits, host pathogen interactions, population structure and potential targets for therapeutic intervention and vaccine development.

Bioterrorism and Infectious Agents

Bioterrorism and Infectious Agents
Author: I.W. Fong
Publisher: Springer Science & Business Media
Total Pages: 284
Release: 2010-03-18
Genre: Medical
ISBN: 1441912665

Compiled by two leading experts in the field, this volume provides a concise, timely, and authoritative review of some of the most problematic infections of the new century. It presents issues and new ideas for preventing and controlling infectious diseases.

Human Melioidosis

Human Melioidosis
Author: S. D. Puthucheary
Publisher: NUS Press
Total Pages: 114
Release: 2002
Genre: Communicable diseases
ISBN: 9789971692612

Infectious diseases account for a third of all deaths in the developing world, yet the pathogens which affect specifically these predominantly poor people attract little attention. Melioidosis is a case in point. This book describes the epidemiology, pathology, pathophysiology, clinical features, diagnosis, management and prevention of an important infection that is little known outside Southeast Asia and Australia.

Stiehm's Immune Deficiencies

Stiehm's Immune Deficiencies
Author: Kathleen E. Sullivan
Publisher: Academic Press
Total Pages: 1334
Release: 2020-05-23
Genre: Medical
ISBN: 0128172959

Stiehm's Immune Deficiencies: Inborn Errors in Immunity, Second Edition, is ideal for physicians and other caregivers who specialize in immunology, allergies, infectious diseases and pulmonary medicine. It provides a validated source of information for care delivery to patients, covering approaches to diagnosis that use both new genetic information and emphasize screening strategies. Management has changed dramatically over the past five years, so approaches to infection and autoimmunity are emphasized in an effort to improve outcomes and disseminate new information on the uses of targeted therapy. - Covers immune deficiencies that are presented in a practical way, providing helpful information for active clinicians - Fills an increasingly deep gap in the information available to clinicians - Presents both clinical management and scientific advances for immune deficiencies - Provides a primary resource for physicians in the field of immunodeficiencies - Includes website access to a range of videos relevant to the topics discussed

Global Burden and Challenges of Melioidosis

Global Burden and Challenges of Melioidosis
Author: Direk Limmathurotsakul
Publisher: MDPI
Total Pages: 272
Release: 2019-03-26
Genre: Medical
ISBN: 303897742X

This book is the definitive reference regarding the global status of melioidosis in 2018. Melioidosis is one of the most neglected tropical diseases (NTDs), so much so that it is not even included in the WHO list of NTDs. Yet modeling suggests that it kills more people worldwide every year than diseases that are much better known, such as leptospirosis and dengue. The reasons for this under-recognition are numerous, including the fact that it mainly affects the disadvantaged rural poor in areas that are poorly supplied with the diagnostic capability to make the diagnosis. In 22 separate articles, expert authors from around the world have summarized what is known about the burden of the disease in humans and animals and the presence of the causative bacterium in the environment in their countries or regions. They have also identified the main obstacles and challenges to establishing the true burden, and to ensure that patients receive accurate diagnosis and optimal care for this all too frequently fatal disease. Rather than focusing on the theoretical risk of the use of Burkholderia pseudomallei as a biological weapon, this book highlights its importance as a clear and present danger to global public health.

Zoonoses - Infections Affecting Humans and Animals

Zoonoses - Infections Affecting Humans and Animals
Author: Andreas Sing
Publisher: Springer
Total Pages: 1127
Release: 2014-12-08
Genre: Medical
ISBN: 940179457X

The book will cover the most important zoonoses with a public health impact and debate actual developments in this field from a One Health perspective. The outline of the book follows a “setting” approach, i.e. special settings of zoonoses with a public health aspect, rather than presenting a simple textbook of an encyclopedic character. Main chapters will deal with zoonoses in the food chain including a special focus on the emerging issue of antibiotic resistance, with zoonoses in domestic and pet animals, in wildlife animal species (including bats as an important infectious agent multiplier), influenza and tuberculosis as most prominent zoonoses, and zoonotic pathogens as bioterroristic agents. Special interest chapters debate non-resolved and currently hotly debated zoonoses (e.g. M. Crohn/paratuberculosis, chronic botulism) as well as the economic and ecological aspects of zoonoses.

Microbial Toxins

Microbial Toxins
Author: P. Gopalakrishnakone
Publisher: Springer
Total Pages: 502
Release: 2018-03-14
Genre: Medical
ISBN: 9789400764484

In recent years, the field of Toxinology has expanded substantially. On the one hand it studies venomous animals, plants and micro organisms in detail to understand their mode of action on targets. While on the other, it explores the biochemical composition, genomics and proteomics of toxins and venoms to understand their three interaction with life forms (especially humans), development of antidotes and exploring their pharmacological potential. Therefore, Toxinology has deep linkages with biochemistry, molecular biology, anatomy and pharmacology. In addition, there is a fast developing applied subfield, clinical toxinology, which deals with understanding and managing medical effects of toxins on human body. Given the huge impact of toxin-based deaths globally, and the potential of venom in generation of drugs for so-far incurable diseases (for example, Diabetes, Chronic Pain), the continued research and growth of the field is imminent. This has led to the growth of research in the area and the consequent scholarly output by way of publications in journals and books. Despite this ever growing body of literature within biomedical sciences, there is still no all-inclusive reference work available that collects all of the important biochemical, biomedical and clinical insights relating to Toxinology. The Handbook of Toxinology aims to address this gap and cover the field of Toxinology comprehensively.

Tropical Dermatology E-Book

Tropical Dermatology E-Book
Author: Steven K Tyring
Publisher: Elsevier Health Sciences
Total Pages: 511
Release: 2016-10-17
Genre: Medical
ISBN: 032333914X

In an increasingly global community, the rapid adaptation of microorganisms has facilitated the return of old communicable diseases and the emergence of new ones. Tropical Dermatology, 2nd Edition, provides a practical, highly illustrated approach to the diagnosis and treatment of a wide range of tropical skin diseases. In a concise and user-friendly format, it offers authoritative coverage of epidemiology, diagnosis, differential diagnosis, pathology, laboratory tests, management, and prevention for both common and rare conditions. - Examines the full range of tropical skin diseases in an easy-to-reference format, with consistently organized, templated chapters. - Structures clinical guidance by disease rather than by microbe or "bug." - Covers the key issues for travelers, important considerations for people working in the tropics, and non-infectious conditions. - Provides authoritative guidance for dermatologists, infectious disease specialists, and travel medicine physicians. - Includes new chapters on Tungiasis, Ebola and Zika virus. - Features updates on emerging diseases and new therapies throughout. - Includes brand-new, "hard-to-find" clinical images, for a total of more than 650 full-color illustrations throughout. - Integrates the knowledge and experience of new international contributors, including recognized experts in dermatology from the United States, Europe, South America, Africa, and Asia. - Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and references from the book on a variety of devices.

Zoonoses

Zoonoses
Author: Rolf Bauerfeind
Publisher: John Wiley & Sons
Total Pages: 548
Release: 2015-12-22
Genre: Medical
ISBN: 1555819257

Zoonoses are a persistent threat to the global human health Today, more than 200 diseases occurring in humans and animals are known to be mutually transmitted. Classical infectious diseases, such as rabies, plague, and yellow fever, have not been eradicated despite major efforts. New zoonotic diseases are on the increase due global conditions such as overpopulation, wars, and food scarcity, which facilitate human contact with rodents, stray animals, and their parasites. In addition, humans are unwittingly becoming accidental hosts and new links in an infectious chain by engaging in activities such as survival training, which involves camping in open areas and consumption of raw or insufficiently cooked food. Zoonotic infections cause a variety of symptoms that often do not provide clear evidence of a known disease. Zoonoses, Fourth Edition, describes most occurring worldwide zoonosis and facilitates the identification, diagnosis and treatment of zoonotic infections. Written by a team of doctors, medical microbiologists and veterinarians, this completely, revised edition covers all aspects of the epidemiology and prevention of zoonotic diseases through clear descriptions of various illnesses. Specifically, this fourth edition covers zoonosis caused by viruses, bacteria, fungi and parasites infections caused by animal bites infections and intoxications by animal foods Iatrogenic transmission of zoonotic pathogens Zoonoses is an indispensable reference for clinicians and laboratorians.