Recent Advances in Scar Biology

Recent Advances in Scar Biology
Author: Rei Ogawa
Publisher: MDPI
Total Pages: 203
Release: 2019-01-29
Genre: Science
ISBN: 303897398X

This book is a printed edition of the Special Issue "Recent Advances in Scar Biology" that was published in IJMS

Textbook on Scar Management

Textbook on Scar Management
Author: Luc Téot
Publisher: Springer Nature
Total Pages: 553
Release: 2020-12-07
Genre: Medical
ISBN: 3030447669

This text book is open access under a CC BY 4.0 license. Written by a group of international experts in the field and the result of over ten years of collaboration, it allows students and readers to gain to gain a detailed understanding of scar and wound treatment – a topic still dispersed among various disciplines. The content is divided into three parts for easy reference. The first part focuses on the fundamentals of scar management, including assessment and evaluation procedures, classification, tools for accurate measurement of all scar-related elements (volume density, color, vascularization), descriptions of the different evaluation scales. It also features chapters on the best practices in electronic-file storage for clinical reevaluation and telemedicine procedures for safe remote evaluation. The second section offers a comprehensive review of treatment and evidence-based technologies, presenting a consensus of the various available guidelines (silicone, surgery, chemical injections, mechanical tools for scar stabilization, lasers). The third part evaluates the full range of emerging technologies offered to physicians as alternative or complementary solutions for wound healing (mechanical, chemical, anti-proliferation). Textbook on Scar Management will appeal to trainees, fellows, residents and physicians dealing with scar management in plastic surgery, dermatology, surgery and oncology, as well as to nurses and general practitioners

The Scar Book

The Scar Book
Author: Andrew C. Krakowski
Publisher: Lippincott Williams & Wilkins
Total Pages: 928
Release: 2017-02-08
Genre: Medical
ISBN: 1496384814

Apply cutting-edge expertise to manage your patients’ scarring issues! Scarring and fibrosis affect millions of people worldwide, and can be devastating both physically and psychologically, whether they result from major trauma such as burns or common conditions such as acne. Put today’s most advanced clinical approaches to work for your patients with The Scar Book: Formation, Mitigation, Rehabilitation, and Prevention! A multidisciplinary team of leading world experts presents the state of the art in scar pathophysiology and treatment, breaking down the barriers between medical disciplines to provide unprecedented holistic guidance.

Mechanisms of Vascular Disease

Mechanisms of Vascular Disease
Author: Robert Fitridge
Publisher: University of Adelaide Press
Total Pages: 589
Release: 2011
Genre: Medical
ISBN: 1922064009

New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

Skin Tissue Engineering and Regenerative Medicine

Skin Tissue Engineering and Regenerative Medicine
Author: Mohammad Albanna
Publisher: Academic Press
Total Pages: 468
Release: 2016-01-14
Genre: Technology & Engineering
ISBN: 012801797X

The skin is the largest human organ system. Loss of skin integrity due to injury or illness results in a substantial physiologic imbalance and ultimately in severe disability or death. From burn victims to surgical scars and plastic surgery, the therapies resulting from skin tissue engineering and regenerative medicine are important to a broad spectrum of patients. Skin Tissue Engineering and Regenerative Medicine provides a translational link for biomedical researchers across fields to understand the inter-disciplinary approaches which expanded available therapies for patients and additional research collaboration. This work expands on the primary literature on the state of the art of cell therapies and biomaterials to review the most widely used surgical therapies for the specific clinical scenarios. - Explores cellular and molecular processes of wound healing, scar formation, and dermal repair - Includes examples of animal models for wound healing and translation to the clinical world - Presents the current state of, and clinical opportunities for, extracellular matrices, natural biomaterials, synthetic biomaterials, biologic skin substitutes, and adult and fetal stem and skin cells for skin regenerative therapies and wound management - Discusses new innovative approaches for wound healing including skin bioprinting and directed cellular therapies

Biology of Pericytes – Recent Advances

Biology of Pericytes – Recent Advances
Author: Alexander Birbrair
Publisher: Springer Nature
Total Pages: 283
Release: 2021-04-08
Genre: Science
ISBN: 3030621294

Pericytes were originally discovered and named more than hundred years ago as contractile cells around the blood vessel endothelial cells. Due to the lack of exclusive markers, pericytes are now defined by a combination of location, morphology and gene expression. Pericytes are attracting increasing attention as important regulators during development and during normal and disturbed organ function. In recent years, remarkable progress has been made in the identification and characterization of pericytes subpopulations and their amazing functions using state-of-art techniques. These advantages facilitated identification of molecular basis of interaction between these cells with several other more well studied cell types, and revealed key signals derived from pericytes involved in homeostasis, regeneration, and disease regulation. In the last ten years, several unexpected roles of pericytes have been discovered. It has been demonstrated that pericytes from different tissues differ in their properties as well as functions. Even more, pericytes are heterogeneous also within the same organ. This book is will describe the major contributions of pericytes to different organs biology in physiological and pathological conditions. The book will teach the readers about this so special cell type that 10 years ago was almost completely forgotten, and it was associated basically only with vascular stability. Recently, it become a very hot topic to work in. Several articles in Nature, Science and Cell have been and are being currently published about this cell type. These recent works are revealing how important those cells are for before unimaginable biological processes. Thus, this book will update us on what are the most novel functions attributed to these cells. Also, will introduce to the young generation all the history about these cells from when they were discovered in different organs till where we are now in this field. So it will be a great book for both cell biology students as well as researchers that will have an update on these cells biology in different organs.

Multiple Sclerosis

Multiple Sclerosis
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 457
Release: 2001-08-10
Genre: Medical
ISBN: 0309072859

Multiple sclerosis is a chronic and often disabling disease of the nervous system, affecting about 1 million people worldwide. Even though it has been known for over a hundred years, no cause or cure has yet been discovered-but now there is hope. New therapies have been shown to slow the disease progress in some patients, and the pace of discoveries about the cellular machinery of the brain and spinal cord has accelerated. This book presents a comprehensive overview of multiple sclerosis today, as researchers seek to understand its processes, develop therapies that will slow or halt the disease and perhaps repair damage, offer relief for specific symptoms, and improve the abilities of MS patients to function in their daily lives. The panel reviews existing knowledge and identifies key research questions, focusing on: Research strategies that have the greatest potential to understand the biological mechanisms of recovery and to translate findings into specific strategies for therapy. How people adapt to MS and the research needed to improve the lives of people with MS. Management of disease symptoms (cognitive impairment, depression, spasticity, vision problems, and others). The committee also discusses ways to build and financially support the MS research enterprise, including a look at challenges inherent in designing clinical trials. This book will be important to MS researchers, research funders, health care advocates for MS research and treatment, and interested patients and their families.

Opportunities in Biotechnology for Future Army Applications

Opportunities in Biotechnology for Future Army Applications
Author: National Research Council
Publisher: National Academies Press
Total Pages: 118
Release: 2001-07-11
Genre: Science
ISBN: 0309075556

This report surveys opportunities for future Army applications in biotechnology, including sensors, electronics and computers, materials, logistics, and medical therapeutics, by matching commercial trends and developments with enduring Army requirements. Several biotechnology areas are identified as important for the Army to exploit, either by direct funding of research or by indirect influence of commercial sources, to achieve significant gains in combat effectiveness before 2025.

Imaging Technologies and Transdermal Delivery in Skin Disorders

Imaging Technologies and Transdermal Delivery in Skin Disorders
Author: Chenjie Xu
Publisher: John Wiley & Sons
Total Pages: 498
Release: 2020-03-09
Genre: Science
ISBN: 3527344608

Provides the latest information on imaging technologies and transdermal delivery in skin disorders This important, timely book covers the latest understanding about today's major skin disorders, the development of imaging technologies for skin diagnosis, and the applications of micro/nano-technologies for the treatment of skin complications. It also places great emphasis on the critical role that interdisciplinary science occupies to achieve the requisite level of understanding of skin conditions and their management, which is essential to creating technologies that work. Imaging Technologies and Transdermal Delivery in Skin Disorders starts by outlining the structural characteristics of skin and skin appendages. It then discusses the key pathways involved in skin growth and development. Clinical presentations, pathophysiological mechanisms, and current clinical practices used to treat diseases affecting the skin are then introduced. Common preclinical models used for studying the mechanisms of diverse skin diseases, validation of novel therapeutic targets, and screening of new drugs to treat these diseases are also covered. The book examines the latest imaging technologies for understanding in vivo skin changes, as well as technologies such as high-resolution ultrasound imaging, quantitative Magnetic Resonance Imaging, high-resolution Optical Coherence Tomography, and emerging hybrid-imaging modalities. It concludes with chapters introducing emerging drug delivery technologies and potential future innovative developments. * Presents up-to-date knowledge of the skin biology and pathologies * Introduces advancements in the topic of imaging technology for tracing the drug delivery process, which is rarely systematically reported by other counterparts * Covers the latest development in three inter-related directions of drug delivery, imaging, and skin disease intersect for skin research * Provides an overview of the latest development of diagnostic and therapeutic technologies for skin diseases Imaging Technologies and Transdermal Delivery in Skin Disorders will be of great interest to analytical chemists, materials scientists, pharmaceutical chemists, clinical chemists, biotechnologists, bioengineers, cosmetics industry, and dermatologists.