Recent Advances In Quantitative Methods In Cancer And Human Health Risk Assessment
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| Author | : Lutz Edler |
| Publisher | : John Wiley & Sons |
| Total Pages | : 510 |
| Release | : 2005-05-27 |
| Genre | : Mathematics |
| ISBN | : 9780470857564 |
Human health risk assessment involves the measuring of risk of exposure to disease, with a view to improving disease prevention. Mathematical, biological, statistical, and computational methods play a key role in exposure assessment, hazard assessment and identification, and dose-response modelling. Recent Advances in Quantitative Methods in Cancer and Human Health Risk Assessment is a comprehensive text that accounts for the wealth of new biological data as well as new biological, toxicological, and medical approaches adopted in risk assessment. It provides an authoritative compendium of state-of-the-art methods proposed and used, featuring contributions from eminent authors with varied experience from academia, government, and industry. Provides a comprehensive summary of currently available quantitative methods for risk assessment of both cancer and non-cancer problems. Describes the applications and the limitations of current mathematical modelling and statistical analysis methods (classical and Bayesian). Includes an extensive introduction and discussion to each chapter. Features detailed studies of risk assessments using biologically-based modelling approaches. Discusses the varying computational aspects of the methods proposed. Provides a global perspective on human health risk assessment by featuring case studies from a wide range of countries. Features an extensive bibliography with links to relevant background information within each chapter. Recent Advances in Quantitative Methods in Cancer and Human Health Risk Assessment will appeal to researchers and practitioners in public health & epidemiology, and postgraduate students alike. It will also be of interest to professionals working in risk assessment agencies.
| Author | : Lutz Edler |
| Publisher | : |
| Total Pages | : 463 |
| Release | : 2005 |
| Genre | : |
| ISBN | : 9787804708578 |
"Recent Advances in Quantitative Methods in Cancer and Human Health Risk Assessment" will appeal to researchers and practitioners in public health & epidemiology, and postgraduate students alike. It will also be of interest to professionals working in risk assessment agencies.
| Author | : Robert A. Fjeld |
| Publisher | : John Wiley & Sons |
| Total Pages | : 532 |
| Release | : 2023-10-24 |
| Genre | : Science |
| ISBN | : 1119675324 |
QUANTITATIVE ENVIRONMENTAL RISK ANALYSIS FOR HUMAN HEALTH An updated edition of the foundational guide to environmental risk analysis Environmental risk analysis is a systematic process essential for the evaluation, management, and communication of the human health risk posed by the release of contaminants to the environment. Performed correctly, risk analysis is an essential tool in the protection of the public from the health hazards posed by chemical and radioactive contaminants. Cultivating the quantitative skills required to perform risk analysis competently is a critical need. Quantitative Environmental Risk Analysis for Human Health meets this need with a thorough, comprehensive coverage of the fundamental knowledge necessary to assess environmental impacts on human health. It introduces readers to a robust methodology for analyzing environmental risk, as well as to the fundamental principles of uncertainty analysis and the pertinent environmental regulations. Now updated to reflect the latest research and new cutting-edge methodologies, this is an essential contribution to the practice of environmental risk analysis. Readers of the second edition of Quantitative Environmental Risk Analysis for Human Health will also find: Detailed treatment of source and release characterization, contaminant migration, exposure assessment, and more New coverage of computer-based analytical methods A new chapter of case studies providing actual, real-world examples of environmental risk assessments Quantitative Environmental Risk Analysis for Human Health is must-have for graduate and advanced undergraduate students in civil engineering, environmental engineering, and environmental science, as well as for risk analysis practitioners in industry, environmental consultants, and regulators.
| Author | : Samuel C. Morris |
| Publisher | : CRC Press |
| Total Pages | : 417 |
| Release | : 2020-07-24 |
| Genre | : Medical |
| ISBN | : 1000104303 |
Based on the National Academy of Sciences approach to quantitative risk assessment. Emphasizes how an accurate assessment of cancer risk must draw on a wide range of disciplines, such as biology, chemistry, physics, engineering, and the social sciences. Provides tables of Poisson confidence limit fa
| Author | : Nigel Bruce |
| Publisher | : John Wiley & Sons |
| Total Pages | : 580 |
| Release | : 2018-02-05 |
| Genre | : Medical |
| ISBN | : 1118665414 |
A practical introduction to epidemiology, biostatistics, and research methodology for the whole health care community This comprehensive text, which has been extensively revised with new material and additional topics, utilizes a practical slant to introduce health professionals and students to epidemiology, biostatistics, and research methodology. It draws examples from a wide range of topics, covering all of the main contemporary health research methods, including survival analysis, Cox regression, and systematic reviews and meta-analysis—the explanation of which go beyond introductory concepts. This second edition of Quantitative Methods for Health Research: A Practical Interactive Guide to Epidemiology and Statistics also helps develop critical skills that will prepare students to move on to more advanced and specialized methods. A clear distinction is made between knowledge and concepts that all students should ensure they understand, and those that can be pursued further by those who wish to do so. Self-assessment exercises throughout the text help students explore and reflect on their understanding. A program of practical exercises in SPSS (using a prepared data set) helps to consolidate the theory and develop skills and confidence in data handling, analysis, and interpretation. Highlights of the book include: Combining epidemiology and bio-statistics to demonstrate the relevance and strength of statistical methods Emphasis on the interpretation of statistics using examples from a variety of public health and health care situations to stress relevance and application Use of concepts related to examples of published research to show the application of methods and balance between ideals and the realities of research in practice Integration of practical data analysis exercises to develop skills and confidence Supplementation by a student companion website which provides guidance on data handling in SPSS and study data sets as referred to in the text Quantitative Methods for Health Research, Second Edition is a practical learning resource for students, practitioners and researchers in public health, health care and related disciplines, providing both a course book and a useful introductory reference.
| Author | : National Research Council |
| Publisher | : National Academies Press |
| Total Pages | : 668 |
| Release | : 1994-01-01 |
| Genre | : Science |
| ISBN | : 030904894X |
The public depends on competent risk assessment from the federal government and the scientific community to grapple with the threat of pollution. When risk reports turn out to be overblownâ€"or when risks are overlookedâ€"public skepticism abounds. This comprehensive and readable book explores how the U.S. Environmental Protection Agency (EPA) can improve its risk assessment practices, with a focus on implementation of the 1990 Clean Air Act Amendments. With a wealth of detailed information, pertinent examples, and revealing analysis, the volume explores the "default option" and other basic concepts. It offers two views of EPA operations: The first examines how EPA currently assesses exposure to hazardous air pollutants, evaluates the toxicity of a substance, and characterizes the risk to the public. The second, more holistic, view explores how EPA can improve in several critical areas of risk assessment by focusing on cross-cutting themes and incorporating more scientific judgment. This comprehensive volume will be important to the EPA and other agencies, risk managers, environmental advocates, scientists, faculty, students, and concerned individuals.
| Author | : Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation |
| Publisher | : National Academies Press |
| Total Pages | : 422 |
| Release | : 2006-03-23 |
| Genre | : Science |
| ISBN | : 0309133343 |
This book is the seventh in a series of titles from the National Research Council that addresses the effects of exposure to low dose LET (Linear Energy Transfer) ionizing radiation and human health. Updating information previously presented in the 1990 publication, Health Effects of Exposure to Low Levels of Ionizing Radiation: BEIR V, this book draws upon new data in both epidemiologic and experimental research. Ionizing radiation arises from both natural and man-made sources and at very high doses can produce damaging effects in human tissue that can be evident within days after exposure. However, it is the low-dose exposures that are the focus of this book. So-called “late” effects, such as cancer, are produced many years after the initial exposure. This book is among the first of its kind to include detailed risk estimates for cancer incidence in addition to cancer mortality. BEIR VII offers a full review of the available biological, biophysical, and epidemiological literature since the last BEIR report on the subject and develops the most up-to-date and comprehensive risk estimates for cancer and other health effects from exposure to low-level ionizing radiation.
| Author | : Louis Anthony Cox Jr. |
| Publisher | : Springer Nature |
| Total Pages | : 543 |
| Release | : 2020-11-06 |
| Genre | : Business & Economics |
| ISBN | : 3030573583 |
This book highlights quantitative risk assessment and modeling methods for assessing health risks caused by air pollution, as well as characterizing and communicating remaining uncertainties. It shows how to apply modern data science, artificial intelligence and machine learning, causal analytics, mathematical modeling, and risk analysis to better quantify human health risks caused by environmental and occupational exposures to air pollutants. The adverse health effects that are caused by air pollution, and preventable by reducing it, instead of merely being statistically associated with exposure to air pollution (and with other many conditions, from cold weather to low income) have proved to be difficult to quantify with high precision and confidence, largely because correlation is not causation. This book shows how to use recent advances in causal analytics and risk analysis to determine more accurately how reducing exposures affects human health risks. Quantitative Risk Analysis of Air Pollution Health Effects is divided into three parts. Part I focuses mainly on quantitative simulation modelling of biological responses to exposures and resulting health risks. It considers occupational risks from asbestos and crystalline silica as examples, showing how dynamic simulation models can provide insights into more effective policies for protecting worker health. Part II examines limitations of regression models and the potential to instead apply machine learning, causal analysis, and Bayesian network learning methods for more accurate quantitative risk assessment, with applications to occupational risks from inhalation exposures. Finally, Part III examines applications to public health risks from air pollution, especially fine particulate matter (PM2.5) air pollution. The book applies freely available browser analytics software and data sets that allow readers to download data and carry out many of the analyses described, in addition to applying the techniques discussed to their own data. http://cox-associates.com:8899/
| Author | : Donna F. Stroup Ph.D, M.Sc. |
| Publisher | : Oxford University Press |
| Total Pages | : 252 |
| Release | : 1998-07-16 |
| Genre | : Medical |
| ISBN | : 9780199771332 |
Public health strives to improve the health of human populations, and prevent disease, disability, and death. Statistics--the science of finding underlying patterns by analyzing variability and errors in collected data--is essential to the understanding of disease patterns in human populations. Other quantitative methods, such as economics, decision theory, and mathematics, now constitute integral parts of the scientific basis for priority-setting and evaluation in public health. This book provides a broad conceptual treatment of the statistical issues underlying core public health functions: outbreak investigations, policy development, economic and program evaluation, managed care, and program operations. The theoretical analysis is illustrated with examples from public health practice. For readers interested in a more detailed treatment, there are extensive references to specialized publications. The authors present a series of quantitative approaches that significantly help public health professionals solve the problems they confront in their day-to-day work. Unlike traditional how-to books in statistics, this volume starts with an overview of the range of problems encountered in public health practice, and then presents methods for facilitating decision making. Statistics in Public Health: Quantitative Approaches to Public Health Problems will serve as a comprehensive desk reference for public health practitioners and as a teaching text for students of public health.
| Author | : Constantine Zervos |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 739 |
| Release | : 2013-11-11 |
| Genre | : Medical |
| ISBN | : 1489907300 |
This volume of the series Advances in Risk Analysis consists of papers presented at the 1988 Annual Meeting of the Society for Risk Analysis, which was held October 30 through November 2 at the Mayflower Hotel in Washington, DC. The papers span the gamut of the increasing number of risk assessment topics addressed by the Society since it held its fIrst annual meeting in June 1981, also in Washington DC. Organized to promote interdisciplinary analyses, the Society approaches risks from three broad perspectives: (1) the impact of various risks on the health of the world's populations and on the environment; (2) the social and political implications of specifIc risks, and (3) the management and reduction of risks through the development of a risk analysis methodology and corresponding data bases. The papers included in this volume typify these three approaches and illustrate their interdependence. For example, both cancer and noncancer health risks are examined for a variety of situations that exist within society. The public's perception of risks and the correlation between that perception and the acceptance or nonacceptance of certain risks is also addressed. In addition, the progress to date on predicting and quantifying specifIc risks, including the risks associated with the construction and use of large engineered systems, is reported. Included among the papers are several dealing with recent current issues, such as the impact of California's Proposition 65, hazardous waste disposal, and chemical accidents.
