Closed Loop Neuroscience

Closed Loop Neuroscience
Author: Ahmed El Hady
Publisher: Academic Press
Total Pages: 304
Release: 2016-09-08
Genre: Medical
ISBN: 0128026413

Closed Loop Neuroscience addresses the technical aspects of closed loop neurophysiology, presenting the implementation of these approaches spanning several domains of neuroscience, from cellular and network neurophysiology, through sensory and motor systems, and then clinical therapeutic devices. Although closed-loop approaches have long been a part of the neuroscientific toolbox, these techniques are only now gaining popularity in research and clinical applications. As there is not yet a comprehensive methods book addressing the topic as a whole, this volume fills that gap, presenting state-of-the-art approaches and the technical advancements that enable their application to different scientific problems in neuroscience. - Presents the first volume to offer researchers a comprehensive overview of the technical realities of employing closed loop techniques in their work - Offers application to in-vitro, in-vivo, and hybrid systems - Contains an emphasis on the actual techniques used rather than on specific results obtained - Includes exhaustive protocols and descriptions of software and hardware, making it easy for readers to implement the proposed methodologies - Encompasses the clinical/neuroprosthetic aspect and how these systems can also be used to contribute to our understanding of basic neurophysiology - Edited work with chapters authored by leaders in the field from around the globe – the broadest, most expert coverage available

Recent Advances and the Future Generation of Neuroinformatics Infrastructure

Recent Advances and the Future Generation of Neuroinformatics Infrastructure
Author: Xi Cheng
Publisher: Frontiers Media SA
Total Pages: 390
Release: 2015-12-11
Genre: Neurosciences. Biological psychiatry. Neuropsychiatry
ISBN: 2889196771

The huge volume of multi-modal neuroimaging data across different neuroscience communities has posed a daunting challenge to traditional methods of data sharing, data archiving, data processing and data analysis. Neuroinformatics plays a crucial role in creating advanced methodologies and tools for the handling of varied and heterogeneous datasets in order to better understand the structure and function of the brain. These tools and methodologies not only enhance data collection, analysis, integration, interpretation, modeling, and dissemination of data, but also promote data sharing and collaboration. This Neuroinformatics Research Topic aims to summarize the state-of-art of the current achievements and explores the directions for the future generation of neuroinformatics infrastructure. The publications present solutions for data archiving, data processing and workflow, data mining, and system integration methodologies. Some of the systems presented are large in scale, geographically distributed, and already have a well-established user community. Some discuss opportunities and methodologies that facilitate large-scale parallel data processing tasks under a heterogeneous computational environment. We wish to stimulate on-going discussions at the level of the neuroinformatics infrastructure including the common challenges, new technologies of maximum benefit, key features of next generation infrastructure, etc. We have asked leading research groups from different research areas of neuroscience/neuroimaging to provide their thoughts on the development of a state of the art and highly-efficient neuroinformatics infrastructure. Such discussions will inspire and help guide the development of a state of the art, highly-efficient neuroinformatics infrastructure.

Closing the Loop Around Neural Systems

Closing the Loop Around Neural Systems
Author: Steve M Potter
Publisher: Frontiers Media SA
Total Pages: 424
Release: 2014-12-03
Genre: Neurophysiology
ISBN: 288919356X

Closed-loop neurophysiology has been accelerated by recent software and hardware developments and by the emergence of novel tools to control neuronal activity with spatial and temporal precision, in which stimuli are delivered in real time based on recordings or behavior. Real-time stimulation feedback enables a wide range of innovative studies of information processing and plasticity in neuronal networks. This Research Topic e-Book comprises 16 Original Research Articles, seven Methods Articles, and seven Reviews, Mini- Reviews, and Perspectives, all peer-reviewed and published in Frontiers in Neural Circuits. The contributions deal with closed loop neurophysiology experiments at a variety of levels of neural circuit complexity. Some include modeling and theoretical analyses. New enabling technologies and techniques are described. Novel work is presented from experiments in vitro, in vivo, and in humans, along with their clinical and technological implications for improving the human condition.

Bioelectronic Medicine

Bioelectronic Medicine
Author: Valentin A. Pavlov
Publisher: Perspectives Cshl
Total Pages: 350
Release: 2019
Genre: Medical
ISBN: 9781621823025

"Cold Spring Harbor perspectives in medicine."

Imaging in Neuroscience and Development

Imaging in Neuroscience and Development
Author: Rafael Yuste
Publisher: CSHL Press
Total Pages: 813
Release: 2005
Genre: Medical
ISBN: 0879696923

As imaging studies have continued to expand in scope and sophistication, this new edition of the highly successful and well–received Imaging Neurons: A Laboratory Manualhas expanded to include development, with over twenty new chapters on such topics as MRI microscopy, imaging early developmental events, and labeling single neurons. Chapters on FRET, FCS/ICS, FRAP, hyperresolution microscopy, single molecule imaging, imaging with quantum dots, and imaging gene expression are included. With over forty full chapters, the manual also includes over forty sections of protocols for imaging techniques.

Recent Advances In Predicting And Preventing Epileptic Seizures - Proceedings Of The 5th International Workshop On Seizure Prediction

Recent Advances In Predicting And Preventing Epileptic Seizures - Proceedings Of The 5th International Workshop On Seizure Prediction
Author: Ronald Tetzlaff
Publisher: World Scientific
Total Pages: 302
Release: 2013-08-28
Genre: Medical
ISBN: 9814525367

This book is to improve our understanding of mechanisms leading to seizures in humans and in developing new therapeutic options. The book covers topics such as recent approaches to seizure control, recent developments in signal processing of interest for seizure prediction, ictogenesis in complex epileptic brain networks, active probing of the pre-seizure state, non-EEG based approaches to the transition to seizures, microseizures and their role in the generation of clinical seizures, the impact of sleep and long-biological cycles on seizure prediction, as well as animal and computational models of seizures and epilepsy. Furthermore the book covers recent developments of international databases and of parallel computing structures based on Cellular Nonlinear Networks that can play an important role in the realization of a portable seizure warning device.

Neural Mechanisms in Behavior

Neural Mechanisms in Behavior
Author: H.B. Barlow
Publisher: Springer Science & Business Media
Total Pages: 319
Release: 2012-12-06
Genre: Medical
ISBN: 1461260639

This book is the product of a two-day symposium held at the University of Texas, Austin, in March 1978. There was double motivation for our hosting a symposium on neural mechanisms in behavior. The 1977-1978 academic year marked both the 50th anniversary of the Department of Psychology at Texas and the 30th anniversary of the famous Hixon Symposium organized by the longest serving member of the department, LLOYD JEFFRESS. PHILIP GOUGH, then chairman of the department, suggested that the department celebrate these two historic events, and honor itself in the process, by holding the first of a series of symposia on topics in experimental psychology. Approval and initial funding for this enterprise came from ROBERT KING, then Dean of Social and Behavioral Sciences; additional funds were pro vided by the Program in Cognitive Science of the Sloan Foundation. Proceeds from the sale of this volume will all pass into a fund to help support subsequent symposia and volumes. At 50 we are clearly a young department, even for a psy chology department, but psychology was at least nominally present from the beginning of The University of Texas in 1883. Then, courses in psychology were offered in the School of Philosophy and had wonderful titles, such as "Mental Science (Strictly Speaking). " In 1898, the first experimental psychology course was offered. (Or at least it was intended to be offered; the catalog indicated that it was contingent upon the availability of necessary equipment.

Opportunities in Neuroscience for Future Army Applications

Opportunities in Neuroscience for Future Army Applications
Author: National Research Council
Publisher: National Academies Press
Total Pages: 136
Release: 2009-07-16
Genre: Social Science
ISBN: 0309127408

Advances and major investments in the field of neuroscience can enhance traditional behavioral science approaches to training, learning, and other applications of value to the Army. Neural-behavioral indicators offer new ways to evaluate how well an individual trainee has assimilated mission critical knowledge and skills, and can also be used to provide feedback on the readiness of soldiers for combat. Current methods for matching individual capabilities with the requirements for performing high-value Army assignments do not include neuropsychological, psychophysiological, neurochemical or neurogenetic components; simple neuropsychological testing could greatly improve training success rates for these assignments. Opportunities in Neuroscience for Future Army Applications makes 17 recommendations that focus on utilizing current scientific research and development initiatives to improve performance and efficiency, collaborating with pharmaceutical companies to employ neuropharmaceuticals for general sustainment or enhancement of soldier performance, and improving cognitive and behavioral performance using interdisciplinary approaches and technological investments. An essential guide for the Army, this book will also be of interest to other branches of military, national security and intelligence agencies, academic and commercial researchers, pharmaceutical companies, and others interested in applying the rapid advances in neuroscience to the performance of individual and group tasks.

Conn's Translational Neuroscience

Conn's Translational Neuroscience
Author: P. Michael Conn
Publisher: Academic Press
Total Pages: 778
Release: 2016-09-28
Genre: Medical
ISBN: 0128025964

Conn's Translational Neuroscience provides a comprehensive overview reflecting the depth and breadth of the field of translational neuroscience, with input from a distinguished panel of basic and clinical investigators. Progress has continued in understanding the brain at the molecular, anatomic, and physiological levels in the years following the 'Decade of the Brain,' with the results providing insight into the underlying basis of many neurological disease processes. This book alternates scientific and clinical chapters that explain the basic science underlying neurological processes and then relates that science to the understanding of neurological disorders and their treatment. Chapters cover disorders of the spinal cord, neuronal migration, the autonomic nervous system, the limbic system, ocular motility, and the basal ganglia, as well as demyelinating disorders, stroke, dementia and abnormalities of cognition, congenital chromosomal and genetic abnormalities, Parkinson's disease, nerve trauma, peripheral neuropathy, aphasias, sleep disorders, and myasthenia gravis. In addition to concise summaries of the most recent biochemical, physiological, anatomical, and behavioral advances, the chapters summarize current findings on neuronal gene expression and protein synthesis at the molecular level. Authoritative and comprehensive, Conn's Translational Neuroscience provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, as well as a clear demonstration of their emerging diagnostic and therapeutic importance. - Provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, while also clearly demonstrating their emerging diagnostic and therapeutic importance - Features contributions from leading global basic and clinical investigators in the field - Provides a great resource for researchers and practitioners interested in the basic science underlying neurological processes - Relates and translates the current science to the understanding of neurological disorders and their treatment

Human Neurophysiology

Human Neurophysiology
Author: Giselher Schalow
Publisher: Nova Biomedical
Total Pages: 734
Release: 2012-12-01
Genre: Medical
ISBN: 9781622574575

To repair the injured, malformed or degenerating human central nervous system, we have to understand the functioning of the healthy human CNS on cellular and integrative levels to learn what changed in the neural networks. Since there is some similarity between development and repair, also the development of the human CNS has to be studied. Especially the strategy of movement-based learning of the CNS to eliminate occurring errors during development is of interest because it can also be used during repair. In this book, movement patters which have the highest rate of re-learning movement are analysed as well as higher mental functions. The therapy using these efficient movement-based learning movements is called Coordination Dynamics Therapy (CDT).