Recent Advances and Clinical Outcomes of Kidney Transplantation

Recent Advances and Clinical Outcomes of Kidney Transplantation
Author: Charat Thongprayoon
Publisher:
Total Pages: 270
Release: 2020-09-10
Genre:
ISBN: 9783039364077

Advances in immunosuppression and kidney transplant techniques have led to significant improvements in the short-term survival of the renal allograft. Long-term graft survival, however, has relatively lagged behind and has now become one of the main problems in kidney transplantation. In this Special Issue, we discuss the recent research developments in kidney transplants that may affect long-term allografts, as well as the survival of the patient. The latest developments in living kidney donation are also explored.

Handbook of Kidney Transplantation

Handbook of Kidney Transplantation
Author: Gabriel M. Danovitch
Publisher: Lippincott Williams & Wilkins
Total Pages: 496
Release: 2012-03-28
Genre: Medical
ISBN: 1451148305

This popular handbook is a practical guide for physicians, surgeons, nurses, and other professionals who manage kidney transplant patients. It is concise, readable, and well-illustrated. Chapters outline the major concerns surrounding renal transplantation and the most successful approaches to problems arising in short-term and long-term patient care. Chapter topics include immunobiology and immunosuppression, as well as chapters on surgery, histocompatibility, and the first three months post-transplant surgery. This thoroughly updated Fifth Edition includes new information on options for patients with end-stage renal disease, immunosuppressive medications and protocols for kidney transplantation, and the first two months following transplant.

Therapeutic Immunosuppression

Therapeutic Immunosuppression
Author: Angus W. Thomson
Publisher: Springer Science & Business Media
Total Pages: 534
Release: 2001
Genre: Medical
ISBN: 9780792368892

This work has broad applications in clinical medicine, ranging from prevention and treatment of organ and bone marrow transplant rejection, management of various autoimmune disorders (for example, rheumatoid arthritis), skin disease and asthma. Whereas traditionally only a small repertoire of immunosuppressive agents was available for clinical use, recent discoveries have significantly increased the number of approved agents, resulting in numerous trials to further evaluate their potential. There is also considerable interest in the potential of cell-based therapies (particularly hematopoietic stem and dendritic cell therapy) of allo- and autoimmunity. Important recent advances in the immunotherapy of allergic diseases are also covered in this book. This volume is intended both for practising physicians and surgeons and for biomedical scientists at the graduate/postdoctoral levels, and is designed to provide the theory behind these various approaches to immunosuppression, and to provide state-of-the-art reviews of current developments in each area.

Diagnostics, Risk Factors, Treatment and Outcomes of Acute Kidney Injury in a New Paradigm

Diagnostics, Risk Factors, Treatment and Outcomes of Acute Kidney Injury in a New Paradigm
Author: Wisit Cheungpasitporn
Publisher: MDPI
Total Pages: 574
Release: 2020-12-10
Genre: Medical
ISBN: 3039360868

Acute kidney injury (AKI) is a frequent clinical syndrome among hospitalized patients, independently associated with both short- and long-term mortality. Previous investigations attempted to identify effective interventions to prevent AKI or promote kidney function recovery in patients with AKI. Most were unsuccessful. Hence, additional studies are required in the field of AKI research. In this Special Issue, we are making a call to action to stimulate researchers and clinicians to submit their studies on AKI conducted in nephrology, internal medicine, critical care, and other disciplines that will provide additional knowledge and skills in the field of AKI research, ultimately to improve patient outcomes.

Living Donor Kidney Transplantation

Living Donor Kidney Transplantation
Author: Jonas Wadström
Publisher: CRC Press
Total Pages: 212
Release: 2005-07-14
Genre: Medical
ISBN: 9781841843162

Living donor kidney (LDK) transplantation has become the definitive approach to the treatment of end-stage renal failure, providing a better quality of life and the best opportunity for survival when compared with dialysis or transplantation from a deceased donor. A timely compendium of the modern day practice of LDK transplantation from a group of outstanding international experts, this text explores a number of controversial aspects of this innovative new technique. Discussing in detail the current situation, the authors also focus on the responsibility of the medical community to the live kidney donor as a patient, and the potential for complacency regarding donor risk. Emphasizing the ethical principles that must dictate medical practice in LDK transplantation for the foreseeable future - voluntarism, informed consent and medical follow-up - this book comprehensively records the best practices currently available.

ABO-incompatible Kidney Transplantation

ABO-incompatible Kidney Transplantation
Author: Kōta Takahashi
Publisher:
Total Pages: 180
Release: 2001
Genre: Medical
ISBN:

ABO incompatible kidney transplantation is indicated for patients for whom no ABO-identical or minor mismatch donor is available. Since the author and his colleagues performed the first ABO-incompatible kidney transplantation in Japan in 1989, 400 such transplantations have been performed in 41 hospitals in Japan and this practice has contributed to a number of new developments. One is a clearer and more suitable model for conceptualising the mechanism of humoral immune response which enables identification of antigens and antibodies and a therapeutic strategy against rejection. The rejection mechanisms are discussed not only from the perspective of immunology but also viewed from different angles, including anatomy, microscopic and macroscopic pathology, molecular biology and haematology. Immunosuppressive therapy is discussed, divided in four categories: extracorporeal immunomodulation with removal of humoral antibodies; drug therapy to suppress cellular immunity; splenectomy; and anticoagulation therapy. Surgical procedures for kidney transplantation and splenectomy are treated, including discussion of the best timing for the latter. The book gives an overview of the current status with statistics and results of questionnaires and ends with discussions of 17 case histories.

EQ-5D Value Sets: Inventory, Comparative Review and User Guide

EQ-5D Value Sets: Inventory, Comparative Review and User Guide
Author: Agota Szende
Publisher: Springer Science & Business Media
Total Pages: 96
Release: 2007-03-06
Genre: Medical
ISBN: 1402055110

This book provides an essential guide to the use of the EuroQol Group’s value sets for working with EQ-5D data. The EQ-5D is a widely used generic health state descriptive system and facilitates the valuation of health and health gain through its pre-existing value sets. This book brings together a comprehensive inventory of these value sets and their characteristics and offers guidance on how to choose which value set for what purpose.