Real-Time Analysis of Biomolecular Interactions

Real-Time Analysis of Biomolecular Interactions
Author: K. Nagata
Publisher: Springer Science & Business Media
Total Pages: 261
Release: 2013-12-11
Genre: Science
ISBN: 4431669701

The metabolism of all living organisms consists of elaborate and complex interactions among numbers of biomolecules, including protein-protein interactions. BIACORE is a new device that uses surface plasmon resonance for kinetic analysis of molecular interactions and automates whole analytical processes. The number of users of BIACORE is increasing worldwide, but until now nothing had been published in English to explain the principles of this new methodology and the kinds of applications it makes available. This updated and revised version of the Japanese original explains the underlying principles of BIACORE, providing concrete examples that utilize the methodology for analysis in areas ranging from basic to applied sciences. With its generous use of illustrations, this book is a valuable source of information for all users of BIACORE.

Handbook of Surface Plasmon Resonance

Handbook of Surface Plasmon Resonance
Author: Richard B. M. Schasfoort
Publisher: Royal Society of Chemistry
Total Pages: 555
Release: 2017-05-30
Genre: Science
ISBN: 1782627308

Surface plasmon resonance (SPR) plays a dominant role in real-time interaction sensing of biomolecular binding events, this book provides a total system description including optics, fluidics and sensor surfaces for a wide researcher audience.

Cellular and Biomolecular Recognition

Cellular and Biomolecular Recognition
Author: Raz Jelinek
Publisher: John Wiley & Sons
Total Pages: 368
Release: 2009-07-10
Genre: Science
ISBN: 3527627022

With its exploration of the scientific and technological characteristics of systems exploiting molecular recognition between synthetic materials, such as polymers and nanoparticles, and biological entities, this is a truly multidisciplinary book bridging chemistry, life sciences, pharmacology and medicine. The authors introduce innovative biomimetic chemical assemblies which constitute platforms for recruitment of cellular components or biological molecules, while also focusing on physical, chemical, and biological aspects of biomolecular recognition. The diverse applications covered include biosensors, cell adhesion, synthetic receptors, cell patterning, bioactive nanoparticles, and drug design.

Visualization of Receptors

Visualization of Receptors
Author: Gerard Morel
Publisher: CRC Press
Total Pages: 458
Release: 1997-02-26
Genre: Science
ISBN: 9780849326448

A multiplicity of methods for visualization are described in Visualization of Receptors. This book of techniques covers immunocytology, radioautography, in situ hybridization, plasmon resonance, RT in vitro PCR, and X-ray crystal structure analysis. Lecturers, researchers, practitioners, technicians, and students will find all the principles and protocols they require and the means of implementing them. Topics discussed include localization of ligands (in vitro or in vivo), visualization of immunoreactivities of ligand and receptor proteins, detection and quantification of mRNA expression, amplification of signals, and determination of 3-D structure. Details of protocols with illustrations of results and commentaries are provided throughout the book.

Photosystem I

Photosystem I
Author: John H. Golbeck
Publisher: Springer Science & Business Media
Total Pages: 744
Release: 2007-05-20
Genre: Science
ISBN: 1402042566

This book summarizes recent advances made in the biophysics, biochemistry, and molecular biology of the enzyme known as Photosystem I, the light-induced plastocyanin: ferredoxin oxidoreductase. The volume provides a unique compilation of chapters that includes information highlighting controversial issues to indicate the frontiers of research and places special emphasis on methodology and practice for new researchers.

Cell Biology

Cell Biology
Author: Julio E. Celis
Publisher: Elsevier
Total Pages: 630
Release: 2005-11-16
Genre: Science
ISBN: 0080454240

This four-volume laboratory manual contains comprehensive state-of-the-art protocols essential for research in the life sciences. Techniques are presented in a friendly step-by-step fashion, providing useful tips and potential pitfalls. The important steps and results are beautifully illustrated for further ease of use. This collection enables researchers at all stages of their careers to embark on basic biological problems using a variety of technologies and model systems. This thoroughly updated third edition contains 165 new articles in classical as well as rapidly emerging technologies. Topics covered include: - Cell and Tissue Culture: Associated Techniques, Viruses, Antibodies, Immunocytochemistry (Volume 1) - Organelle and Cellular Structures, Assays (Volume 2) - Imaging Techniques, Electron Microscopy, Scanning Probe and Scanning Electron Microscopy, Microdissection, Tissue Arrays, Cytogenetics and In Situ Hybridization, Genomics and Transgenic Knockouts and Knock-down Methods (Volume 3) - Transfer of Macromolecules, Expression Systems, Gene Expression Profiling (Volume 4) - Indispensable bench companion for every life science laboratory - Provides the latest information on the plethora of technologies needed to tackle complex biological problems - Includes numerous illustrations, some in full color, supporting steps and results

Biochemistry and Molecular Biology of Plant Hormones

Biochemistry and Molecular Biology of Plant Hormones
Author: P.J.J. Hooykaas
Publisher: Elsevier
Total Pages: 565
Release: 1999-05-13
Genre: Science
ISBN: 008086094X

This book provides up-to-date coverage at an advanced level of a range of topics in the biochemistry and molecular biology of plant hormones, with particular emphasis on biosynthesis, metabolism and mechanisms of action. Each contribution is written by acknowledged experts in the field, providing definitive coverage of the field. No other modern book covers this subject matter at such an advanced level so comprehensively. It will be invaluable to university libraries and scientists in the plant biotechnology industries.

Biomarkers and Biosensors

Biomarkers and Biosensors
Author: Ajit Sadana
Publisher: Newnes
Total Pages: 703
Release: 2014-12-08
Genre: Medical
ISBN: 0444537953

Biomarkers and Biosensors offers thorough coverage of biomarker/biosensor interaction, current research trends, and future developments in applications of drug discovery. This book is useful to researchers in this field as well as clinicians interested in new developments in early detection and diagnosis of disease or the mode of operation of biomarkers. Biomarkers and Biosensors also emphasizes kinetics, and clearly delineates how this influences the biomarker market. - Offers thorough coverage of the kinetics of biomarker interaction with the biosensor surface - Provides evidence-based approach to evaluate effectiveness - Provides pharmaceutical chemists the possibilities and methodology in assessing the effectiveness of new drugs - Provides the information needed for the selection of the best biomarker for a specific application