Quinone Based Compounds In Drug Discovery
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| Author | : Khalid Rehman Hakeem |
| Publisher | : Academic Press |
| Total Pages | : 0 |
| Release | : 2025-01-02 |
| Genre | : Medical |
| ISBN | : 9780443241260 |
Quinone-Based Compounds in Drug Discovery: Trends and Applications provides a comprehensive and up-to-date overview of the latest advances in the field of drug discovery using quinone-based materials. This book covers various aspects of quinone-based materials such as their synthesis, characterization, and applications in drug discovery, consolidating current research on a single volume. The book introduces quinones in the pharmacology context and then describes the current developments in the development of drugs for key diseases and conditions. The final chapters deal with the regulatory and commercial framework to take quinone-based drugs to the market. Quinone-Based Compounds in Drug Discovery: Trends and Applications benefits a wide range of readers including researchers, scientists, and graduate students in the field of drug discovery, Chemists and biochemists will also benefit from the contents of this book.
| Author | : Umar Ali Dar |
| Publisher | : Elsevier |
| Total Pages | : 460 |
| Release | : 2024-10-25 |
| Genre | : Medical |
| ISBN | : 0443241252 |
Quinone-Based Compounds in Drug Discovery: Trends and Applications provides a comprehensive and up-to-date overview of the latest advances in the field of drug discovery using quinone-based materials. The book covers various aspects of quinone-based materials such as their synthesis, characterization, and applications in drug discovery, consolidating current research. It introduces quinones in the pharmacology context and then describes current developments in drugs for key diseases and conditions. Final chapters deal with the regulatory and commercial framework to take quinone-based drugs to the market. This book will benefit a wide range of readers, including researchers, scientists, and graduate students in the field of drug discovery. Chemists and biochemists will also benefit from the contents of this book. - Covers various aspects of quinone-based materials, including their synthesis, characterization, and applications in drug discovery - Includes specific chapters on antibiotic, neuroprotective, anticancer, antioxidant, and cardio protection through the action of quinones - Incorporates information on the regulatory, intellectual property, commercialization, and clinical development of quinone-based drugs
| Author | : Belakatte Parameshwarappa Nandeshwarappa |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 250 |
| Release | : 2020-05-27 |
| Genre | : Science |
| ISBN | : 1789859433 |
The book ‘Organic Synthesis - A Nascent Relook’ is a compendium of the recent progress in all aspects of organic chemistry including bioorganic chemistry, organo-metallic chemistry, asymmetric synthesis, heterocyclic chemistry, natural product chemistry, catalytic, green chemistry and medicinal chemistry, polymer chemistry, as well as analytical methods in organic chemistry. The book presents the latest developments in these fields. The chapters are written by chosen experts who are internationally known for their eminent research contributions. Organic synthesis is the complete chemical synthesis of a target molecule. In this book, special emphasis is given to the synthesis of various bioactive heterocycles. Careful selection of various topics in this book will serve the rightful purpose for the chemistry community and the industrial houses at all levels.
| Author | : Olga Genilloud |
| Publisher | : Royal Society of Chemistry |
| Total Pages | : 435 |
| Release | : 2012 |
| Genre | : Medical |
| ISBN | : 1849733619 |
An integrated review of the most recent trends in natural products, drug discovery, and key lead candidates that are outstanding for their chemistry and biology in novel drug development.
| Author | : Carmen Avendaño |
| Publisher | : Elsevier |
| Total Pages | : 767 |
| Release | : 2015-06-11 |
| Genre | : Science |
| ISBN | : 0444626670 |
Medicinal Chemistry of Anticancer Drugs, Second Edition, provides an updated treatment from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Antitumor chemotherapy is a very active field of research, and a huge amount of information on the topic is generated every year. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells, and resistance to antitumor drugs continues to be investigated. While these therapies are in their infancy, they hold promise of more effective therapies with fewer side effects. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a sorely needed update from the point of view of medicinal chemistry and drug design. - Presents information in a clear and concise way using a large number of figures - Historical background provides insights on how the process of drug discovery in the anticancer field has evolved - Extensive references to primary literature
| Author | : Jeremy I Levin |
| Publisher | : Royal Society of Chemistry |
| Total Pages | : 526 |
| Release | : 2015 |
| Genre | : Medical |
| ISBN | : 1849737010 |
This series provides a comprehensive resource for postgraduate students and for scientists in academia or industry wanting to learn topics outside their own areas of expertise.
| Author | : Gordon W. Gribble |
| Publisher | : John Wiley & Sons |
| Total Pages | : 704 |
| Release | : 2016-08-08 |
| Genre | : Science |
| ISBN | : 0470512180 |
Of the myriad of heterocycles known to man, the indole ring stands foremost for its remarkably versatile chemistry, its enormous range of biological activities, and its ubiquity in the terrestrial and marine environments. The indole ring continues to be discovered in natural products and to be employed in man-made pharmaceuticals and other materials. Given the enormous resurgence in indole ring synthesis over the past decade — highlighted by the power of transition metal catalysis — this authoritative guide addresses the need for a comprehensive presentation of the myriad of methods for constructing the indole ring, from the ancient to the modern, and from the obscure to the well-known. Following presentation of the classic indole ring syntheses and many newer methods, coverage continues with indole ring syntheses via pyrroles, indolines, oxindoles, isatins, radical and photochemical reactions, aryne cycloadditions. This extensive volume concludes with the modern transition metal–catalyzed indole ring syntheses that utilize copper, palladium, rhodium, gold, ruthenium, platinum, and other metals to fashion the indole ring Indole Ring Synthesis is a comprehensive, authoritative and up-to-date guide to the synthesis of this important heterocycle for organic chemists, pharmaceutical researchers and those interested in the chemistry of natural products.
| Author | : Victor Kuete |
| Publisher | : Newnes |
| Total Pages | : 917 |
| Release | : 2013-06-19 |
| Genre | : Science |
| ISBN | : 0124059368 |
The pharmacopoeias of most African countries are available and contain an impressive number of medicinal plants used for various therapeutic purposes. Many African scholars have distinguished themselves in the fields of organic chemistry, pharmacology, and pharmacognosy and other areas related to the study of plant medicinal plants. However, until now, there is no global standard book on the nature and specificity of chemicals isolated in African medicinal plants, as well as a book bringing together and discussing the main bioactive metabolites of these plants. This book explores the essence of natural substances from African medicinal plants and their pharmacological potential. In light of possible academic use, this book also scans the bulk of African medicinal plants extract having promising pharmacological activities. - The book contains data of biologically active plants of Africa, plant occurring compounds and synthesis pathways of secondary metabolites - This book explores the essence of natural substances from African medicinal plants and their pharmacological potential - The authors are world reknowned African Scientists
| Author | : Pavel Anzenbacher |
| Publisher | : John Wiley & Sons |
| Total Pages | : 755 |
| Release | : 2012-05-29 |
| Genre | : Medical |
| ISBN | : 352732903X |
A practice-oriented desktop reference for medical professionals, toxicologists and pharmaceutical researchers, this handbook provides systematic coverage of the metabolic pathways of all major classes of xenobiotics in the human body. The first part comprehensively reviews the main enzyme systems involved in biotransformation and how they are orchestrated in the body, while parts two to four cover the three main classes of xenobiotics: drugs, natural products, environmental pollutants. The part on drugs includes more than 300 substances from five major therapeutic groups (central nervous system, cardiovascular system, cancer, infection, and pain) as well as most drugs of abuse including nicotine, alcohol and "designer" drugs. Selected, well-documented case studies from the most important xenobiotics classes illustrate general principles of metabolism, making this equally useful for teaching courses on pharmacology, drug metabolism or molecular toxicology. Of particular interest, and unique to this volume is the inclusion of a wide range of additional xenobiotic compounds, including food supplements, herbal preparations, and agrochemicals.
| Author | : Singh, Ajeet |
| Publisher | : IGI Global |
| Total Pages | : 754 |
| Release | : 2022-06-24 |
| Genre | : Science |
| ISBN | : 1668451301 |
A great deal of interest has been generated recently in the isolation, characterization, and biological activity of phytochemicals. Phytochemicals have the potential to enhance pharmaceuticals and drug discovery. As such, there is an urgent need for current research in the global scope of phytochemicals including the chemical and physical characteristics, analytical procedures, biological activity, safety, and industrial applications. The Handbook of Research on Advanced Phytochemicals and Plant-Based Drug Discovery examines the applications of bioactive molecules from a health perspective, examining the pharmacological aspects of medicinal plants, the phytochemical and biological activities of different natural products, and ethnobotany and medicinal properties. Moreover, it presents a novel dietary approach for human disease management. Covering topics such as computer-aided drug design, government regulation, and medicinal plant taxonomy, this major reference work is beneficial to pharmacists, medical practitioners, phytologists, hospital administrators, government officials, faculty and students of higher education, librarians, researchers, and academicians.
