Brain Mapping: The Methods

Brain Mapping: The Methods
Author: Arthur W. Toga
Publisher: Academic Press
Total Pages: 912
Release: 2002-09-25
Genre: Medical
ISBN: 9780126930191

The number of scientists and laboratories involved with brain mapping is increasing exponentially; and the second edition of this comprehensive reference has also grown much larger than the first (published in 1996), including, for example, five chapters on structural and functional MRI where the fi

Quantitative MRI of the Spinal Cord

Quantitative MRI of the Spinal Cord
Author: Julien Cohen-Adad
Publisher: Academic Press
Total Pages: 331
Release: 2014-01-16
Genre: Medical
ISBN: 0123972825

Quantitative MRI of the Spinal Cord is the first book focused on quantitative MRI techniques with specific application to the human spinal cord. This work includes coverage of diffusion-weighted imaging, magnetization transfer imaging, relaxometry, functional MRI, and spectroscopy. Although these methods have been successfully used in the brain for the past 20 years, their application in the spinal cord remains problematic due to important acquisition challenges (such as small cross-sectional size, motion, and susceptibility artifacts). To date, there is no consensus on how to apply these techniques; this book reviews and synthesizes state-of-the-art methods so users can successfully apply them to the spinal cord. Quantitative MRI of the Spinal Cord introduces the theory behind each quantitative technique, reviews each theory's applications in the human spinal cord and describes its pros and cons, and suggests a simple protocol for applying each quantitative technique to the spinal cord. - Chapters authored by international experts in the field of MRI of the spinal cord - Contains "cooking recipes—examples of imaging parameters for each quantitative technique—designed to aid researchers and clinicians in using them in practice - Ideal for clinical settings

Primary Progressive Multiple Sclerosis

Primary Progressive Multiple Sclerosis
Author: M. Filippi
Publisher: Springer Science & Business Media
Total Pages: 188
Release: 2012-12-06
Genre: Medical
ISBN: 8847022347

"Why are there no effective treatments for my condition? Why do researchers exclude patients with primary progressive multiple sclerosis from enrolling in clinical trials? Please let me know if you hear of studies that I might be allowed to enter or treatments that I could try for my condition. " Thus, in recent years, the sad lament of the patient with primary progressive MS (PPMS). This variant, often in the guise of a chronic progressive myelopathy or, less commonly, progressive cerebellar or bulbar dysfunction, usually responds poorly to corticosteroids and rarely seems to benefit to a significant degree from intensive immunosuppressive treatments. In recent years, most randomized clin ical trials have excluded PPMS patients on two counts. Clinical worsening devel ops slowly in PPMS and may not be recognized during the course of a 2-or 3-year trial even in untreated control patients. This factor alone adds to the potential for a type 2 error or, at the very least, inflates the sample size and duration of the trial. In addition, there is mounting evidence that progressive axonal degeneration and neuronal loss (rather than active, recurrent inflammation) may be important components of the pathology in this form of the disease. Although contemporary trials are evaluating whether PPMS patients may benefit from treatment with the ~-interferons and glatiramer acetate, preliminary, uncontrolled clinical experi ence suggests that the results may not be dramatic.

Translational Research in Traumatic Brain Injury

Translational Research in Traumatic Brain Injury
Author: Daniel Laskowitz
Publisher: CRC Press
Total Pages: 388
Release: 2016-04-21
Genre: Medical
ISBN: 1498766579

Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme

MRI Atlas of Human White Matter

MRI Atlas of Human White Matter
Author: Kenichi Oishi
Publisher: Academic Press
Total Pages: 266
Release: 2010-11-12
Genre: Science
ISBN: 0123820820

MRI Atlas of Human White Matter presents an atlas to the human brain on the basis of T 1-weighted imaging and diffusion tensor imaging. A general background on magnetic resonance imaging is provided, as well as the basics of diffusion tensor imaging. An overview of the principles and limitations in using this methodology in fiber tracking is included. This book describes the core white-matter structures, as well as the superficial white matter, the deep gray matter, and the cortex. It also presents a three-dimensional reconstruction and atlas of the brain white-matter tracts. The Montreal Neurological Institute coordinates, which are the most widely used, are adopted in this book as the primary coordinate system. The Talairach coordinate system is used as the secondary coordinate system. Based on magnetic resonance imaging and diffusion tensor imaging, the book offers a full segmentation of 220 white-matter and gray-matter structures with boundaries. - Visualization of brain white matter anatomy via 3D diffusion tensor imaging (DTI) contrasts and enhances relationship of anatomy to function - Full segmentation of 170+ brain regions more clearly defines structure boundaries than previous point-and-annotate anatomical labeling, and connectivity is mapped in a way not provided by traditional atlases

Quantifying Morphology and Physiology of the Human Body Using MRI

Quantifying Morphology and Physiology of the Human Body Using MRI
Author: L. Tugan Muftuler
Publisher: CRC Press
Total Pages: 529
Release: 2013-05-02
Genre: Medical
ISBN: 1439852650

In the medical imaging field, clinicians and researchers are increasingly moving from the qualitative assessment of printed images to the quantitative evaluation of digital images since the quantitative techniques often improve diagnostic accuracy and complement clinical assessments by providing objective criteria. Despite this growing interest, the field lacks a comprehensive body of knowledge. Filling the need for a complete manual on these novel techniques, Quantifying Morphology and Physiology of the Human Body Using MRI presents a wide range of quantitative MRI techniques to study the morphology and physiology of the whole body, from the brain to musculoskeletal systems. Illustrating the growing importance of quantitative MRI, the book delivers an indispensable reference for readers who would like to explore in vivo MRI techniques to quantify changes in the morphology and physiology of tissues caused by various disease mechanisms. With internationally renowned experts sharing their insight on the latest developments, the book goes beyond conventional MRI contrast mechanisms to include new techniques that measure electromagnetic and mechanical properties of tissues. Each chapter offers comprehensive information on data acquisition, processing, and analysis techniques as well as clinical applications. The text organizes the techniques based on their primary use either in the brain or the body. Some of the techniques, such as diffusion-weighted imaging and diffusion tensor imaging, span several application areas, including brain imaging, cancer imaging, and musculoskeletal imaging. The book also covers up-and-coming quantitative techniques that explore tissue properties other than the presence of protons (or other MRI-observable nuclei) and their interactions with their environment. These novel techniques provide unique information about the electromagnetic and mechanical properties of tissues and introduce new frontiers of study into disease mechanisms.

Diseases of the Brain, Head and Neck, Spine 2020–2023

Diseases of the Brain, Head and Neck, Spine 2020–2023
Author: Juerg Hodler
Publisher: Springer Nature
Total Pages: 252
Release: 2020-02-14
Genre: Medical
ISBN: 303038490X

This open access book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography. The book also includes a synopsis of pediatric imaging. IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text. It will particularly appeal to general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic expertise, as well as clinicians from other specialties who are interested in imaging for their patient care.

Neuroimaging in Epilepsy

Neuroimaging in Epilepsy
Author: Harry Chugani, MD
Publisher: Oxford University Press
Total Pages:
Release: 2010-11-23
Genre: Medical
ISBN: 0199711526

Perhaps the most important achievements in the field of epileptology in the past two decades have been in the neuroimaging and genetic breakthroughs as applied to patients with epilepsy. Indeed, neuroimaging has become a vital part in the study of epilepsy, affecting broad aspects of the disorder ranging from diagnosis and classification to treatment and prognosis. Neuroimaging in epilepsy encompasses many different approaches that have reached various levels of expertise across epilepsy centers worldwide. This book discusses every imaging modality used to gather information on epilepsy. Each technique is described by world experts and epilepsy centers worldwide.

Brain Network Analysis

Brain Network Analysis
Author: Moo K. Chung
Publisher: Cambridge University Press
Total Pages: 343
Release: 2019-06-27
Genre: Computers
ISBN: 110718486X

This coherent mathematical and statistical approach aimed at graduate students incorporates regression and topology as well as graph theory.

Cardiovascular Imaging and Image Analysis

Cardiovascular Imaging and Image Analysis
Author: Ayman El-Baz
Publisher: CRC Press
Total Pages: 436
Release: 2018-10-03
Genre: Medical
ISBN: 0429806221

This book covers the state-of-the-art approaches for automated non-invasive systems for early cardiovascular disease diagnosis. It includes several prominent imaging modalities such as MRI, CT, and PET technologies. There is a special emphasis placed on automated imaging analysis techniques, which are important to biomedical imaging analysis of the cardiovascular system. Novel 4D based approach is a unique characteristic of this product. This is a comprehensive multi-contributed reference work that will detail the latest developments in spatial, temporal, and functional cardiac imaging. The main aim of this book is to help advance scientific research within the broad field of early detection of cardiovascular disease. This book focuses on major trends and challenges in this area, and it presents work aimed to identify new techniques and their use in biomedical image analysis. Key Features: Includes state-of-the art 4D cardiac image analysis Explores the aspect of automated segmentation of cardiac CT and MR images utilizing both 3D and 4D techniques Provides a novel procedure for improving full-cardiac strain estimation in 3D image appearance characteristics Includes extensive references at the end of each chapter to enhance further study