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| Author | : Jonathan Pevsner |
| Publisher | : John Wiley & Sons |
| Total Pages | : 792 |
| Release | : 2005-03-04 |
| Genre | : Science |
| ISBN | : 0471459178 |
Wiley is proud to announce the publication of the first ever broad-based textbook introduction to Bioinformatics and Functional Genomics by a trained biologist, experienced researcher, and award-winning instructor. In this new text, author Jonathan Pevsner, winner of the 2001 Johns Hopkins University "Teacher of the Year" award, explains problem-solving using bioinformatic approaches using real examples such as breast cancer, HIV-1, and retinal-binding protein throughout. His book includes 375 figures and over 170 tables. Each chapter includes: Problems, discussion of Pitfalls, Boxes explaining key techniques and math/stats principles, Summary, Recommended Reading list, and URLs for freely available software. The text is suitable for professionals and students at every level, including those with little to no background in computer science.
| Author | : Robert C. Smart |
| Publisher | : John Wiley & Sons |
| Total Pages | : 804 |
| Release | : 2013-03-05 |
| Genre | : Science |
| ISBN | : 1118679725 |
An essential resource for graduate students, academic and industrial toxicologists, and environmental health scientists and professionals Over the course of thirty years and three editions, Introduction to Biochemical Toxicology has been an important source for coverage of the ongoing quest to define the biochemical, cellular, and molecular events induced by toxicants at the cellular and organismic levels. Now, as the principles and methods of molecular and cellular biology as well as genomic sciences play an ever increasing role in mechanistic toxicology, significant changes have been made to the book, resulting in this important new edition-now titled Molecular and Biochemical Toxicology, Fourth Edition. Much more than an introductory text, this crucial new edition has been completely revised to provide timely and thorough coverage of the underlying biochemical, molecular, and cellular mechanisms through which toxicants produce their adverse effects. Toxicological issues are covered from the molecule to the cell to the organ level. Complex methods used in toxicology are also described in a straightforward, easy-to-understand style. Additional features of this new edition include: New chapters that explore the interface between toxicology and genomic sciences, including: bioinformatics, proteomics, metabolomics, and toxicogenomics Increased emphasis on structure, mechanism, and regulation of xenobiotic metabolizing enzymes, toxicogenetics, and xenobiotic transporters Additional new chapters on: molecular epidemiology and genetic susceptibility, DNA damage and mutagenesis, DNA repair, mechanisms of cell death, mitochondrial dysfunction, metals, reproductive toxicology, developmental toxicology, and reactive oxygen/metabolites and toxicity Molecular and Biochemical Toxicology, Fourth Edition guides graduate students, toxicologists, and environmental health professionals through the principles of molecular and biochemical toxicology and the complex mechanisms of toxicity. Whether it's used in the classroom or in industry, research, or academia, this book is essential for anyone interested in understanding the molecular mechanisms through which toxicants produce adverse effects.
| Author | : Paul Dear |
| Publisher | : Scion Publishing Ltd |
| Total Pages | : 329 |
| Release | : 2007-09-24 |
| Genre | : Science |
| ISBN | : 1907904379 |
INTRODUCTION (Paul H. Dear) 1. Database resources for wet-bench scientists (Neil Hall and Lynn Schriml) 2. Navigating sequenced genomes (Melody Clark and Thomas Schlitt) 3. Sequence similarity searches (Jaap Heringa and Walter Pirovano) 4. Gene prediction (Marie-Adele Rajandream) 5. Prediction of non coding transcripts (Alex Bateman and Sam Griffiths-Jones) 6. Finding regulatory elements in DNA sequence (Debraj GuhaThakurta and Gary Stormo) 7. Expressed sequence tags (Arthur Gruber) 8. Protein structure, classification and prediction (Arthur Lesk) 9. Gene ontology (Vineet Sangar) 10. Prediction of protein function (Rodrigo Lopez) 11. Multiple sequence alignment (Burkhard Morgenstern) 12. Inferring phylogenetic relationships from sequence data (Peter Foster) Appendix Index
| Author | : Andreas D. Baxevanis |
| Publisher | : John Wiley & Sons |
| Total Pages | : 647 |
| Release | : 2020-02-12 |
| Genre | : Science |
| ISBN | : 1119335965 |
Praise for the third edition of Bioinformatics "This book is a gem to read and use in practice." —Briefings in Bioinformatics "This volume has a distinctive, special value as it offers an unrivalled level of details and unique expert insights from the leading computational biologists, including the very creators of popular bioinformatics tools." —ChemBioChem "A valuable survey of this fascinating field. . . I found it to be the most useful book on bioinformatics that I have seen and recommend it very highly." —American Society for Microbiology News "This should be on the bookshelf of every molecular biologist." —The Quarterly Review of Biolog" The field of bioinformatics is advancing at a remarkable rate. With the development of new analytical techniques that make use of the latest advances in machine learning and data science, today’s biologists are gaining fantastic new insights into the natural world’s most complex systems. These rapidly progressing innovations can, however, be difficult to keep pace with. The expanded fourth edition of the best-selling Bioinformatics aims to remedy this by providing students and professionals alike with a comprehensive survey of the current field. Revised to reflect recent advances in computational biology, it offers practical instruction on the gathering, analysis, and interpretation of data, as well as explanations of the most powerful algorithms presently used for biological discovery. Bioinformatics, Fourth Edition offers the most readable, up-to-date, and thorough introduction to the field for biologists at all levels, covering both key concepts that have stood the test of time and the new and important developments driving this fast-moving discipline forwards. This new edition features: New chapters on metabolomics, population genetics, metagenomics and microbial community analysis, and translational bioinformatics A thorough treatment of statistical methods as applied to biological data Special topic boxes and appendices highlighting experimental strategies and advanced concepts Annotated reference lists, comprehensive lists of relevant web resources, and an extensive glossary of commonly used terms in bioinformatics, genomics, and proteomics Bioinformatics is an indispensable companion for researchers, instructors, and students of all levels in molecular biology and computational biology, as well as investigators involved in genomics, clinical research, proteomics, and related fields.
| Author | : Arthur Lesk |
| Publisher | : Oxford University Press, USA |
| Total Pages | : 394 |
| Release | : 2014 |
| Genre | : Science |
| ISBN | : 0199651566 |
Lesk provides an accessible and thorough introduction to a subject which is becoming a fundamental part of biological science today. The text generates an understanding of the biological background of bioinformatics.
| Author | : B.D. Singh |
| Publisher | : Springer |
| Total Pages | : 542 |
| Release | : 2015-06-26 |
| Genre | : Science |
| ISBN | : 8132223160 |
Marker-assisted plant breeding involves the application of molecular marker techniques and statistical and bioinformatics tools to achieve plant breeding objectives in a cost-effective and time-efficient manner. This book is intended for beginners in the field who have little or no prior exposure to molecular markers and their applications, but who do have a basic knowledge of genetics and plant breeding, and some exposure to molecular biology. An attempt has been made to provide sufficient basic information in an easy-to-follow format, and also to discuss current issues and developments so as to offer comprehensive coverage of the subject matter. The book will also be useful for breeders and research workers, as it offers a broad range of up-to-the-year information, including aspects like the development of different molecular markers and their various applications. In the first chapter, the field of marker-assisted plant breeding is introduced and placed in the proper perspective in relation to plant breeding. The next three chapters describe the various molecular marker systems, while mapping populations and mapping procedures including high-throughput genotyping are discussed in the subsequent five chapters. Four chapters are devoted to various applications of markers, e.g. marker-assisted selection, genomic selection, diversity analysis, finger printing and positional cloning. In closing, the last two chapters provide information on relevant bioinformatics tools and the rapidly evolving field of phenomics.
| Author | : Caroline Watt |
| Publisher | : Routledge |
| Total Pages | : 399 |
| Release | : 2017-07-05 |
| Genre | : Body, Mind & Spirit |
| ISBN | : 1351912828 |
Many people believe that they have experienced paranormal phenomena and others claim to possess psychic abilities. For the past hundred years or so, researchers have undertaken systematic and scientific work into these alleged experiences and abilities. This collection of articles provides readers with a general sense of the methods used in this research, the findings that have been obtained and the controversies generated by this work. They cover a wide range of issues, including the psychology of paranormal belief, investigations into ghosts and hauntings, laboratory research into extra-sensory perception and psychokinesis, and controlled tests of psychics and mediums. An introductory essay sets each of the selected papers in context and provides additional references for those wishing to delve deeper into the issues surrounding each of the areas covered.
| Author | : M Sandra Wood |
| Publisher | : Routledge |
| Total Pages | : 305 |
| Release | : 2013-10-18 |
| Genre | : Language Arts & Disciplines |
| ISBN | : 1317951247 |
Valuable to both the health professional and information provider, this book provides a comprehensive and detailed look at online biomedical database searching by end users. Experts fully assess the numerous implications of end user searching and synthesize a wide variety of views and successful practices. By examining the types of users, institutional settings, products used, and applications, this important volume probes the specific variations among programs and provides a solid overview of end user searching in the health science field. The volume includes informative chapters on determining content and structure of online educational materials, training the end user, the issues in implementing end user search systems, and much more.
| Author | : Victor Aladjev |
| Publisher | : Fultus Corporation |
| Total Pages | : 565 |
| Release | : 2004 |
| Genre | : Algebra |
| ISBN | : 1596820004 |
Book Description The book represents a library of well-designed software, which well supplements the already available Maple software with the orientation towards the widest circle of the Maple users, greatly enhancing its usability and effectiveness. The current library version contains tools (more than 570 procedures and program modules) that are oriented onto wide enough spheres of computing and information processing. The library is structurally similar to the main Maple library and is supplied with the advanced Help system about the tools located in it. In addition, the library is logically connected with the main Maple library, providing access to the tools contained in it similarly to the package tools. The library will be of special interest above all to those who use Maple of releases 6 - 9.5 not only as a highly intellectual calculator but also as environment for programming of different problems in own professional activities. The represented source codes of the library tools, using both the effective and the non-standard technique, can serve as an useful enough practical programming guide on the Maple language. Author Biography Professor Aladjev V. was born on June 14, 1942 in the town Grodno (Byelorussia). Now, he is the First vice-president of the International Academy of Noosphere and the president of Tallinn Research Group, whose scientific results have received international recognition, first, in the field of mathematical theory of Cellular Automata (CA). He is member of a series of Russian and International Academies. Aladjev V. is the author of more than 300 scientific publications, including 60 books, published in many countries. He participates as a member of the organizing committee and/or a guest lecturer in many international scientific forums in mathematics and cybernetics. Category: NonFiction/Science/Mathematics/Mathematical & Statistical Software/Algebra
| Author | : Timothy C. Haas |
| Publisher | : John Wiley & Sons |
| Total Pages | : 224 |
| Release | : 2011-01-13 |
| Genre | : Nature |
| ISBN | : 0470979550 |
The decision to implement environmental protection options is a political one. These, and other political and social decisions affect the balance of the ecosystem and how the point of equilibrium desired is to be reached. This book develops a stochastic, temporal model of how political processes influence and are influenced by ecosystem processes and looks at how to find the most politically feasible plan for managing an at-risk ecosystem. Finding such a plan is accomplished by first fitting a mechanistic political and ecological model to a data set composed of observations on both political actions that impact an ecosystem and variables that describe the ecosystem. The parameters of this fitted model are perturbed just enough to cause human behaviour to change so that desired ecosystem states occur. This perturbed model gives the ecosystem management plan needed to reach desired ecosystem states. To construct such a set of interacting models, topics from political science, ecology, probability, and statistics are developed and explored. Key features: Explores politically feasible ways to manage at-risk ecosystems. Gives agent-based models of how social groups affect ecosystems through time. Demonstrates how to fit models of population dynamics to mixtures of wildlife data. Presents statistical methods for fitting models of group behaviour to political action data. Supported by an accompanying website featuring datasets and JAVA code. This book will be useful to managers and analysts working in organizations charged with finding practical ways to sustain biodiversity or the physical environment. Furthermore this book also provides a political roadmap to help lawmakers and administrators improve institutional environmental management decision making.
