Protides of the Biological Fluids

Protides of the Biological Fluids
Author: H. Peeters
Publisher: Elsevier
Total Pages: 525
Release: 2013-10-02
Genre: Medical
ISBN: 1483148386

Protides of the Biological Fluids examines protides of the biological fluids and covers topics ranging from the use of DNA probes to diagnose inherited diseases and receptors to the conformation and function of biologically active peptides. This text has 115 chapters and begins by demonstrating the existence of gene families common to several vertebrates and which evolved by intragenic duplication. The chapters that follow focus on the use of DNA probes in the analysis of inherited disorders such as thalassemia and hemophilia. The reader is then introduced to receptors, especially for peptides. Receptors on circulating cells, hormone receptors, receptors involved in cancer, and immunoglobulin receptors are explored. The section on the conformation and function of biologically active peptides considers the methods including spectroscopic methods, crystallography, and theoretical conformational analysis. In particular, the use of synchrotron X-radiation in biological crystallography and of 2D NMR spectroscopy in the identification of folded structures in immunogenic peptides is highlighted. This book will be of value to biologists and biochemists.

Clinical Biochemistry

Clinical Biochemistry
Author: Herbert Spiegel
Publisher: Elsevier
Total Pages: 247
Release: 2012-12-02
Genre: Science
ISBN: 0323159273

Clinical Biochemistry: Contemporary Theories and Techniques, Volume 1 is a collection of papers that deals with the biochemistry of aging, managerial techniques, the evaluation of kits, and autoimmune diseases. One paper discusses laboratory management for clinical chemists—the administration of people, the application of budgets, the planning process, and the adoption of decision-making strategies. The government has also issued federal legislations such as the "Clinical Laboratory Improvement Act, 1967" and the "National Heath Planning and Resources Development Act of 1974" which are changing the way laboratories are doing business. Another paper describes areas of safety concerns specific to the environment of the laboratory that require technologies not readily available to the laboratory technician. These safety problems concern radioactivity and infectious etiologic agents. Another paper discusses criteria recommendations for kit selection in clinical laboratories, for example, the list issued by the Center for Disease Control and the standards issued by the National Committee for Clinical Laboratory Standards. Another paper explains the uses of mathematics in clinical chemistry, including the application of the Allen Correction, the Henderson-Hasselbalch Equations, empirical curve fitting, standard deviation, standard error. Other papers present guidelines in dealing with autoimmune diseases and in determining specific proteins in plasma, cerebrospinal fluid, and other biological fluids. This collection is suitable for clinic and laboratory administrators and managers, for chemical chemists, and investigators or technicians involved in laboratory work.

Distribution and Biological Role

Distribution and Biological Role
Author: Endre A. Balazs
Publisher: Academic Press
Total Pages: 620
Release: 2013-09-24
Genre: Science
ISBN: 1483257649

The Amino Sugars: The Chemistry and Biology of Compounds Containing Amino Sugars, Volume IIA: Distribution and Biological Role focuses on the chemistry, physical chemistry, and biochemistry of naturally occurring and synthetically prepared amino sugars and amino sugar-containing molecules, as well as the biological and medical importance of these molecules. The selection first offers information on the distribution of amino sugars in microorganisms, plants, and invertebrates and amino sugars and macromolecules containing amino sugars in liver. Discussions focus on microorganisms, invertebrates, amino sugar composition, catabolism of amino sugars, and metabolic interrelationships between amino sugars and other sugars. The text then takes a look at amino sugars and macromolecules containing amino sugars in kidney and amino sugar-containing compounds in urine. The publication takes a look at glycoproteins in salivary glands, saliva, and sputum; glycosaminoglycans and glycoproteins in skin; and amino sugar-containing compounds in tumors. The text also evaluates glycosaminoglycans in umbilical cord and glycosaminoglycans and glycoproteins in synovial fluid. The selection is a dependable reference for readers interested in the study of amino sugars.

Biotechnology of Plasma Proteins

Biotechnology of Plasma Proteins
Author: Roger L. Lundblad
Publisher: CRC Press
Total Pages: 460
Release: 2012-08-08
Genre: Medical
ISBN: 1439850275

The fractionation of human blood plasma can be considered to be a mature industry, with the basic technology, alcohol fractionation, dating back at least to the 1940s. Many of the products described in the current work have been approved biologics since the 1950s. The information gathered from the development of plasma proteins has proved vital to