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| Author | : Helmut Sies |
| Publisher | : Academic Press |
| Total Pages | : 440 |
| Release | : 2002 |
| Genre | : Active oxygen |
| ISBN | : 0121822516 |
This volume of Methods in Enzymology is a companion to Volume 347 and addresses direct sensing of reactive oxygen species and related free radicals by thiol enzymes and proteins.
| Author | : |
| Publisher | : Elsevier |
| Total Pages | : 549 |
| Release | : 2002-03-12 |
| Genre | : Science |
| ISBN | : 0080496954 |
This volume of Methods in Enzymology is concerned with the rapidly developing field of selenoprotein synthesis and its related molecular genetics. Progressive information on the topics of proteins as redox sensors, selenoproteins, and the thioredoxin system is studied using methods such as bioinformatics, DNA chip technology, cell biology, molecular genetics, and enzymology. The information on novel selenoproteins identified from genomic sequence data, as well as current knowledge on glutathione peroxidases, selenoprotein P, iodothyronine deiodinases, and thioredoxin reductases, is presented in a method-based approach.
| Author | : |
| Publisher | : Elsevier |
| Total Pages | : 439 |
| Release | : 2002-03-06 |
| Genre | : Science |
| ISBN | : 0080496962 |
This volume of Methods in Enzymology is a companion to Volume 347 and addresses direct sensing of reactive oxygen species and related free radicals by thiol enzymes and proteins.
| Author | : |
| Publisher | : Academic Press |
| Total Pages | : 404 |
| Release | : 2002-03-08 |
| Genre | : Science |
| ISBN | : 9780121822514 |
This volume of Methods in Enzymology is a companion to Volume 347 and addresses direct sensing of reactive oxygen species and related free radicals by thiol enzymes and proteins.
| Author | : |
| Publisher | : Academic Press |
| Total Pages | : 0 |
| Release | : 2002-02-22 |
| Genre | : Science |
| ISBN | : 9780121822514 |
This volume of Methods in Enzymology is a companion to Volume 347 and addresses direct sensing of reactive oxygen species and related free radicals by thiol enzymes and proteins.
| Author | : Loutfy H. Madkour |
| Publisher | : Academic Press |
| Total Pages | : 782 |
| Release | : 2020-06-27 |
| Genre | : Medical |
| ISBN | : 0128224967 |
Reactive Oxygen Species (ROS), Nanoparticles, and Endoplasmic Reticulum (ER) Stress-Induced Cell Death Mechanisms presents the role of ROS?mediated pathways cellular signaling stress, endoplasmic reticulum (ER) stress, oxidative stress, oxidative damage, nanomaterials, and the mechanisms by which metalloids and nanoparticles induce their toxic effects. The book covers the ecotoxicology of environmental heavy metal ions and free radicals on macromolecules cells organisms, heavy metals?induced cell responses, oxidative stress, the source of oxidants, and the roles of ROS, oxidative stress and oxidative damage mechanisms. It also examines the nanotoxicity, cytotoxicity and genotoxicity mechanisms of nanomaterials and the effects of nanoparticle interactions. Antioxidant defense therapy and strategies for treatment round out the book, making it an ideal resource for researchers and professional scientists in toxicology, environmental chemistry, environmental science, nanomaterials and the pharmaceutical sciences. - Covers the ecotoxicology of environmental heavy metal ions and the interactions between specific heavy metals?induced cell responses and oxidative stress - Provides a better understanding of the mechanism of nanomaterial-induced toxicity as a first defense for hazard prevention - Covers recent advances in new nanomedication technologies for the effects of NPs on oxidative stress, ROS and ER stress - Discusses the effects of interactions between antioxidant defense therapy, ROS and strategies for treatment
| Author | : Soumen Bhattacharjee |
| Publisher | : Springer |
| Total Pages | : 197 |
| Release | : 2019-05-10 |
| Genre | : Science |
| ISBN | : 8132239415 |
This book highlights the latest advances made in the niche area of Reactive Oxygen Species and Redox processes in plants. It offers a valuable guide for researchers and students alike, providing insights into sensing, detox scavenging, the role in oxidative deterioration, and signaling associated with redox-regulatory processes in plants. The book also dramatically demonstrates how these amazingly resourceful molecular species and radicals are poised at the core of a sophisticated network of signaling pathways, and act as vital regulators of plants’ cell physiology and cellular responses to the environment. The molecular language associated with ROS-mediated signal transduction, which produces modulations in gene expression that determine plants’ stress acclamatory performance, is also discussed. The book subsequently provides information on current trends in redox proteomics and genomics, which include efforts to gain a fuller understanding of these redox players’ role in cellular processes, and to further the application of this knowledge to technology and agriculture. Given its scope and format, the book offers a valuable asset for students of Plant Sciences, Agriculture, and Molecular Biology, as well as readers engaged in research on and teaching ROS Biology.
| Author | : Nicholas Smirnoff |
| Publisher | : John Wiley & Sons |
| Total Pages | : 320 |
| Release | : 2008-04-15 |
| Genre | : Science |
| ISBN | : 1405171464 |
Reactive oxygen species (ROS) are produced during the interaction of metabolism with oxygen. As ROS have the potential to cause oxidative damage by reacting with biomolecules, research on ROS has concentrated on the oxidative damage that results from exposure to environmental stresses and on the role of ROS in defence against pathogens. However, more recently, it has become apparent that ROS also have important roles as signalling molecules. A complex network of enzymatic and small molecule antioxidants controls the concentration of ROS and repairs oxidative damage, and research is revealing the complex and subtle interplay between ROS and antioxidants in controlling plant growth, development and response to the environment. This book covers these new developments, generally focussing on molecular and biochemical details and providing a point of entry to the detailed literature. It is directed at researchers and professionals in plant molecular biology, biochemistry and cell biology, in both the academic and industrial sectors.
| Author | : Luis A. del Río |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 245 |
| Release | : 2009-06-22 |
| Genre | : Science |
| ISBN | : 3642003907 |
Oxygen (O ) appeared in significant amounts in the Earth’s atmosphere over 2. 2 2 billion years ago, largely due to the evolution of photosynthesis by cyanobacteria (Halliwell 2006). The O molecule is a free radical, as it has two impaired electrons 2 that have the same spin quantum number. This spin restriction makes O prefer to 2 accept its electrons one at a time, leading to the generation of the so-called reactive oxygen species (ROS). The chemical nature of these species dictates that they can create damage in cells. This has contributed to the creation of the “oxidative stress” concept; in this view, ROS are unavoidable toxic products of O metabolism and 2 aerobic organisms have evolved antioxidant defences to protect against this tox- ity (Halliwell 1981; Fridovich 1998). Indeed, even in present-day plants, which are full of antioxidants, much of the protein synthetic activity of chloroplasts is used to replace oxidatively damaged D1 and other proteins (Halliwell 2006). Yet, the use of the “oxidative stress” term implies that ROS exert their effects through indiscriminate widespread inactivation of cellular functions. In this context, ROS must not be able to react with lipids, proteins or nucleic acids in order to avoid any damage to vital cellular components. However, genetic evidence has suggested that, in planta, purely physicoche- cal damage may be more limited than previously thought (Foyer and Noctor 2005).
| Author | : Lawrence J. Berliner |
| Publisher | : Springer Nature |
| Total Pages | : 237 |
| Release | : 2020-08-08 |
| Genre | : Science |
| ISBN | : 303047318X |
This book describes the methods of analysis and determination of oxidants and oxidative stress in biological systems. Reviews and protocols on select methods of analysis of ROS, RNS, oxygen, redox status, and oxidative stress in biological systems are described in detail. It is an essential resource for both novices and experts in the field of oxidant and oxidative stress biology.
