Protein Modules in Signal Transduction

Protein Modules in Signal Transduction
Author: Anthony J. Pawson
Publisher: Springer Science & Business Media
Total Pages: 375
Release: 2012-12-06
Genre: Science
ISBN: 3642804810

This volume in the series Current Topics in Microbiology and Immunology focuses on protein modules in signal transduction. Topics covered include: functions of SH2 and SH3 domains; structure and function of LIM domains; and the IRS-signalling system.

Cell Biology by the Numbers

Cell Biology by the Numbers
Author: Ron Milo
Publisher: Garland Science
Total Pages: 399
Release: 2015-12-07
Genre: Science
ISBN: 1317230698

A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid

Biochemistry of Signal Transduction and Regulation

Biochemistry of Signal Transduction and Regulation
Author: Gerhard Krauss
Publisher: John Wiley & Sons
Total Pages: 558
Release: 2006-03-06
Genre: Science
ISBN: 3527605762

This all-new edition of a classic text has been thoroughly revised to keep pace with the rapid progress in signal transduction research. With didactic skill and clarity the author relates the observed biological phenomena to the underlying biochemical processes. Directed to advanced students, teachers, and researchers in biochemistry and molecular biology, this book describes the molecular basis of signal transduction, regulated gene expression, the cell cycle, tumorigenesis and apoptosis. "Provides a comprehensive account of cell signaling and signal transduction and, where possible, explains these processes at the molecular level" (Angewandte Chemie) "The clear and didactic presentation makes it a textbook very useful for students and researchers not familiar with all aspects of cell regulation." (Biochemistry) "This book is actually two books: Regulation and Signal Transduction." (Drug Research)

Cellular Signal Processing

Cellular Signal Processing
Author: Friedrich Marks
Publisher: Garland Science
Total Pages: 982
Release: 2017-05-17
Genre: Medical
ISBN: 1351677217

Cellular Signal Processing offers a unifying view of cell signaling based on the concept that protein interactions act as sophisticated data processing networks that govern intracellular and extracellular communication. It is intended for use in signal transduction courses for undergraduate and graduate students working in biology, biochemistry, bioinformatics, and pharmacology, as well as medical students. The text is organized by three key topics central to signal transduction: the protein network, its energy supply, and its evolution. It covers all important aspects of cell signaling, ranging from prokaryotic signal transduction to neuronal signaling, and also highlights the clinical aspects of cell signaling in health and disease. This new edition includes expanded coverage of prokaryotes, as well as content on new developments in systems biology, epigenetics, redox signaling, and small, non-coding RNA signaling.

Protein Kinases and Stress Signaling in Plants

Protein Kinases and Stress Signaling in Plants
Author: Girdhar K. Pandey
Publisher: John Wiley & Sons
Total Pages: 560
Release: 2020-12-03
Genre: Science
ISBN: 1119541565

A comprehensive review of stress signaling in plants using genomics and functional genomic approaches Improving agricultural production and meeting the needs of a rapidly growing global population requires crop systems capable of overcoming environmental stresses. Understanding the role of different signaling components in plant stress regulation is vital to developing crops which can withstand abiotic and biotic stresses without loss of crop yield and productivity. Emphasizing genomics and functional genomic approaches, Protein Kinases and Stress Signaling in Plants is a comprehensive review of cutting-edge research on stress perception, signal transduction, and stress response generation. Detailed chapters cover a broad range of topics central to improving agricultural production developing crop systems capable of overcoming environmental stresses to meet the needs of a rapidly growing global population. This book describes the field of protein kinases and stress signaling with a special emphasis on functional genomics. It presents a highly valuable contribution in the field of stress perception, signal transduction and generation of responses against one or multiple stress signals. This timely resource: Summarizes the role of various kinases involved in stress management Enumerates the role of TOR, GSK3-like kinase, SnRK kinases in different physiological conditions Examines mitogen-activated protein kinases (MAPKs) in different stresses Describes the different aspects of calcium signaling under different stress conditions Examines photo-activated kinases (PAPKs) in varying light conditions Briefs the presence of tyrosine kinases in plants Highlights the cellular functions of receptor ]like protein kinases (RLKs) Possible implication of these kinases in developing stress tolerant crops Protein Kinases and Stress Signaling in Plants: Functional Genomic Perspective is an essential resource for researchers and students in the fields of plant molecular biology and signal transduction, plant responses to stress, plant cell signaling, plant protein kinases, plant biotechnology, transgenic plants and stress biology.

Systems Biology for Signaling Networks

Systems Biology for Signaling Networks
Author: Sangdun Choi
Publisher: Springer Science & Business Media
Total Pages: 900
Release: 2010-08-09
Genre: Science
ISBN: 1441957979

System Biology encompasses the knowledge from diverse fields such as Molecular Biology, Immunology, Genetics, Computational Biology, Mathematical Biology, etc. not only to address key questions that are not answerable by individual fields alone, but also to help in our understanding of the complexities of biological systems. Whole genome expression studies have provided us the means of studying the expression of thousands of genes under a particular condition and this technique had been widely used to find out the role of key macromolecules that are involved in biological signaling pathways. However, making sense of the underlying complexity is only possible if we interconnect various signaling pathways into human and computer readable network maps. These maps can then be used to classify and study individual components involved in a particular phenomenon. Apart from transcriptomics, several individual gene studies have resulted in adding to our knowledge of key components that are involved in a signaling pathway. It therefore becomes imperative to take into account of these studies also, while constructing our network maps to highlight the interconnectedness of the entire signaling pathways and the role of that particular individual protein in the pathway. This collection of articles will contain a collection of pioneering work done by scientists working in regulatory signaling networks and the use of large scale gene expression and omics data. The distinctive features of this book would be: Act a single source of information to understand the various components of different signaling network (roadmap of biochemical pathways, the nature of a molecule of interest in a particular pathway, etc.), Serve as a platform to highlight the key findings in this highly volatile and evolving field, and Provide answers to various techniques both related to microarray and cell signaling to the readers.

Histidine Kinases in Signal Transduction

Histidine Kinases in Signal Transduction
Author: Masayori Inouye
Publisher: Elsevier
Total Pages: 539
Release: 2002-11-13
Genre: Science
ISBN: 0080534015

Living cells are constantly sensing environmental changes, and their abilities to sense these changes and adapt to them are essential for their survival. In bacteria, histidine kinases are the major sensors for these environmental stresses, enabling cells to adapt to new growth conditions. Written by leading experts in the field, this book provides an up-to-date and comprehensive review on the structure and function of histidine kinases. It also provides extensive information on the physiological roles of histidine kinases in bacteria and eukaryotes. An an essential reference for cell biologists, microbiologists, molecular biologists, and biochemists interested in signal transduction. Experimental biologists and pharmacologists studying signal transduction systems in living organisms will also find it a valuable research tool. - The first comprehensive book on the roles of histidine kinases in cells - 23 in-depth chapters written by leading experts in the field - Describes the most recent advances in the field of signal transduction

Basic Science of Cancer

Basic Science of Cancer
Author: Gary Kruh
Publisher: Springer Science & Business Media
Total Pages: 296
Release: 2000-08-24
Genre: Medical
ISBN:

In recent years, great strides have been made in the field of cancer research. Now, with Basic Science of Cancer, a range of interrelated topics such as tumor suppressor genes, apoptosis, transcriptional regulation, pharmacology of anticancer drugs, cytogenetic techniques, oncogenes, and signal transduction are thoroughly addressed. Written for oncologists and healthcare professionals, this new comprehensive reference also discusses modern research techniques used to investigate the molecular etiology and treatment of human cancer. Topics are described using nontechnical terms. Together, complete reference listings and over 200 illustrations provide an extensive, yet introductory, look into the complex field of cancer.