Protein Design And The Development Of New Therapeutics And Vaccines
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| Author | : Jerry B. Hook |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 491 |
| Release | : 2013-11-11 |
| Genre | : Medical |
| ISBN | : 146845739X |
Based on a symposium held November 1988, in King of Prussia, Penn. Among the topics: structural analysis of proteins, protein folding and stability, receptor design and regulation, guanine nucleotide binding protein family, modeling and structure prediction in macromolecules, protein engineering and
| Author | : Tarun Kumar Bhatt |
| Publisher | : Academic Press |
| Total Pages | : 310 |
| Release | : 2021-01-21 |
| Genre | : Business & Economics |
| ISBN | : 0128214759 |
The Design and Development of Novel Drugs and Vaccines: Principles and Protocols presents both in silico methods and experimental protocols for vaccine and drug design and development, critically reviewing the most current research and emphasizing approaches and technologies that accelerate and lower the cost of product development. Sections review the technologies and approaches used to identify, characterize and establish a protein as a new drug and vaccine target, cover several molecular methods for in vitro studies of the desired target, and present various physiological parameters for in vivo studies. The book includes preclinical trials and research, along with information on FDA approval. Covers both in silico methods and experimental protocols for vaccine and drug development in a single, accessible volume Offers a holistic accounting of how developments in bioinformatics and large experimental datasets can be used in the development of vaccines and drugs Shows researchers the entire gamut of current therapies, ranging from computational inputs to animal studies Reviews the most current, cutting-edge research available on vaccine and drug design and development
| Author | : Rossen Donev |
| Publisher | : Academic Press |
| Total Pages | : 192 |
| Release | : 2015-06-08 |
| Genre | : Science |
| ISBN | : 0128028696 |
Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology series has been the essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins. Each thematically organized volume is guest edited by leading experts in a broad range of protein-related topics. - Describes advances in application of powerful techniques in a wide bioscience area - Chapters are written by authorities in their field - Targeted to a wide audience of researchers, specialists, and students - The information provided in the volume is well supported by a number of high quality illustrations, figures, and tables
| Author | : Dev Bukhsh Singh |
| Publisher | : Springer Nature |
| Total Pages | : 387 |
| Release | : 2023-03-01 |
| Genre | : Psychology |
| ISBN | : 981198249X |
This book provides an overview of the essential characteristics and clinical applications of therapeutic proteins against human diseases, including cancers, immune disorders, infections, and other diseases. It presents the latest advancements in protein engineering techniques for producing desirable therapeutic proteins. The book also covers the strategies used to formulate and deliver systemic therapeutic proteins, approved protein therapeutics and their targets, and pharmacogenetic biomarkers. Further, it discusses challenges associated with the clinical implications of therapeutic proteins, including safety, immunogenicity, protein stability, degradation, and efficacy. It illustrates the development of biosimilar antibodies, optimization strategies for producing biobetter antibodies, and presents fundamental concepts about biosuperior therapeutics. Lastly, it includes a discussion about protein-based vaccines against bacterial and viral infections.
| Author | : National Research Council |
| Publisher | : National Academies Press |
| Total Pages | : 118 |
| Release | : 2001-07-11 |
| Genre | : Science |
| ISBN | : 0309075556 |
This report surveys opportunities for future Army applications in biotechnology, including sensors, electronics and computers, materials, logistics, and medical therapeutics, by matching commercial trends and developments with enduring Army requirements. Several biotechnology areas are identified as important for the Army to exploit, either by direct funding of research or by indirect influence of commercial sources, to achieve significant gains in combat effectiveness before 2025.
| Author | : Raphael Guerois |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 303 |
| Release | : 2008-02-04 |
| Genre | : Science |
| ISBN | : 1597451169 |
Protein Design: Methods and Applications presents the most up-to-date protein design and engineering strategies so that readers can undertake their own projects with a maximum chance of success. The authors present integrated computational approaches that require various degrees of computational complexity, and the major accomplishments that have been achieved in the design and structural characterization of helical peptides and proteins.
| Author | : Rossen Donev |
| Publisher | : Academic Press |
| Total Pages | : 434 |
| Release | : 2022-05-06 |
| Genre | : Science |
| ISBN | : 0323992307 |
Protein Design and Structure, Volume 130 in the Advances in Protein Chemistry and Structural Biology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Advances in Protein Chemistry and Structural Biology series Includes the latest information on protein design and structure
| Author | : A Krishna Prasad |
| Publisher | : Royal Society of Chemistry |
| Total Pages | : 236 |
| Release | : 2022-11-09 |
| Genre | : Medical |
| ISBN | : 1839162589 |
Vaccine development is a complex and time consuming process that differs from the development of conventional pharmaceuticals. Primarily, vaccines are intended for use in healthy individuals as a preventative measure, requiring a long and rigorous process of research and many years of testing and development prior to clinical trials and regulatory approval. The average time for the development of vaccines to clinical is 12 to 15 years. Vaccine Development: From Concept to Clinic is a detailed overview of the development of new vaccines, covering the entire process and addresses all classes of vaccines from a processing, development and regulatory viewpoint. Utilising successful case studies the book will provide insight to the issues scientists face when producing a vaccine, the steps involved and will serve as an ideal reference tool regarding state-of-the-art vaccine development. This book is an ideal companion for any researchers working in vaccine discovery and development or with an interest in the field.
| Author | : Millicent O. Sullivan |
| Publisher | : Humana |
| Total Pages | : 0 |
| Release | : 2023-11-03 |
| Genre | : Science |
| ISBN | : 9781071634684 |
This volume covers the latest key aspects of therapeutic protein applications. Chapters in this book cover topics such as the discovery, production, and conjugation of protein-proteins with discussions on the direction of future development and advancements; ways to use these engineering proteins for therapeutic and vaccine applications; and the use of modified protein nanocarriers. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Therapeutic Proteins: Methods and Protocols is a valuable resource for any researcher who are interested in learning more about the field of therapeutic proteins.
| Author | : National Library of Medicine (U.S.) |
| Publisher | : |
| Total Pages | : 700 |
| Release | : 1991 |
| Genre | : Medicine |
| ISBN | : |
First multi-year cumulation covers six years: 1965-70.
