Aggregation of Therapeutic Proteins

Aggregation of Therapeutic Proteins
Author: Wei Wang
Publisher: John Wiley & Sons
Total Pages: 400
Release: 2010-12-28
Genre: Medical
ISBN: 1118043588

This book gives pharmaceutical scientists an up-to-date resource on protein aggregation and its consequences, and available methods to control or slow down the aggregation process. While significant progress has been made in the past decade, the current understanding of protein aggregation and its consequences is still immature. Prevention or even moderate inhibition of protein aggregation has been mostly experimental. The knowledge in this book can greatly help pharmaceutical scientists in the development of therapeutic proteins, and also instigate further scientific investigations in this area. This book fills such a need by providing an overview on the causes, consequences, characterization, and control of the aggregation of therapeutic proteins.

Analysis of Aggregates and Particles in Protein Pharmaceuticals

Analysis of Aggregates and Particles in Protein Pharmaceuticals
Author: Hanns-Christian Mahler
Publisher: John Wiley & Sons
Total Pages: 480
Release: 2011-12-20
Genre: Medical
ISBN: 1118150562

This book describes how to address the analysis of aggregates and particles in protein pharmaceuticals, provides a comprehensive overview of current methods and integrated approaches used to quantify and characterize aggregates and particles, and discusses regulatory requirements. Analytical methods covered in the book include separation, light scattering, microscopy, and spectroscopy.

Elsevier Comprehensive Guide To PGMEE With Companion Website - Volume 2

Elsevier Comprehensive Guide To PGMEE With Companion Website - Volume 2
Author: Exam
Publisher: Elsevier India
Total Pages: 756
Release: 2009
Genre:
ISBN: 9788131216200

" 4 Volumes covering 19 subjects with an extensive summary on each subject " 10 years (1999 - 2008) question papers of All India PGMEE and AIIMS PGMEE with answers and explanations This book offers you 6 months FREE access to the Elsevier ExamZoneTM website specially designed for PGME preparations" Monthly Mock Tests with answers, explanations and a subject wise performance summary " Simulated tests of recently concluded PGME exams" Ask an Expert to clarify your doubts " List of medical institutes offering PG courses " Exam calender updates you with the upcoming exams, application availability, due date for form submissions, etc. Elsevier ExamZoneTM is a brand developed to focus on exam preparatory materials and testing tools.All rights in the trademark ExamZone" are reserved with Reed Elsevier India Pvt. Ltd

Peptides: Step-by-step the Complete Guide to Unlock Physical & Mental Health (Effective Use for Managing Diabetes Heart Diseases Cancer Arthritis Neurological Disorders)

Peptides: Step-by-step the Complete Guide to Unlock Physical & Mental Health (Effective Use for Managing Diabetes Heart Diseases Cancer Arthritis Neurological Disorders)
Author: Robert Mills
Publisher: Robert Mills
Total Pages: 165
Release: 101-01-01
Genre: Medical
ISBN:

This process involves amino acids, the deficiency of which leads to a lack of peptides. This often provokes premature aging and increases Peptides are protein combinations required by the body no less than B vitamins. They are directly involved in many internal processes of the body, mainly related to metabolism and the absorption of micronutrients. Due to modern diets, many people are deficient in them. This workbook includes: · The basic concept of peptides · How peptides work in the skin · Benefits of peptide · Peptides in hair · Peptides in food · And a lot of other useful information. This means you can achieve remarkable results, such as accelerated healing post-injury, enhanced performance in daily activities, and a visibly rejuvenated appearance, with minimal risk of dependency or adverse effects. Showing you exactly how these therapies can be a game-changer in your health strategy.

Bioinformatics Scientist- The Comprehensive Guide

Bioinformatics Scientist- The Comprehensive Guide
Author: VIRUTI SHIVAN
Publisher: Viruti Satyan Shivan
Total Pages: 221
Release:
Genre: Science
ISBN:

Dive into the groundbreaking realm of bioinformatics with "Bioinformatics Scientist- The Comprehensive Guide," your ultimate resource for mastering the intricacies of biological data analysis. This guide demystifies the complex world of genetic codes, protein databases, and computational biology, providing an unparalleled journey into the heart of modern biology. Without the need for images or illustrations, the book focuses purely on the rich, detailed narrative and insightful analyses, ensuring an engaging and immersive reading experience. Whether you're a budding scientist, a seasoned researcher, or simply a curious mind, this book promises to transform your understanding of biology, offering a fresh perspective on how data can unlock the mysteries of life itself. In an era where information is abundant yet clarity is scarce, this comprehensive guide stands out by not only covering the technical aspects of bioinformatics but also by connecting the dots between computational techniques and their real-world applications in solving biological problems. Through vivid hypothetical scenarios and personal anecdotes from experts in the field, readers are taken on a captivating journey from the basics of DNA sequencing to the forefront of genetic research. The book emphasizes the critical role of bioinformatics in advancing healthcare, environmental conservation, and our understanding of evolution, making it an essential addition to the library of anyone looking to make a mark in the biological sciences.

Protein Aggregation

Protein Aggregation
Author: Andrzej Stanisław Cieplak
Publisher: Springer Nature
Total Pages: 673
Release: 2022-10-30
Genre: Science
ISBN: 1071625977

The volume details techniques, methods, and conceptual developments to further the study of protein aggregation with emphasis on the pleiomorphic proteins implicated in etiology of neurodegeneration. Chapters guide readers through in vitro and in vivo studies of fibrillization and liquid-liquid phase separation processes, and offer a comprehensive account of the state-of-art of structural studies of protein aggregation. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Protein Aggregation: Methods and Protocols aims to be useful and practical guide to new researchers and experts looking to expand their knowledge.

Protein Self-Assembly

Protein Self-Assembly
Author: Jennifer J. McManus
Publisher: Humana
Total Pages: 266
Release: 2020-08-08
Genre: Science
ISBN: 9781493996803

This volume explores experimental and computational approaches to measuring the most widely studied protein assemblies, including condensed liquid phases, aggregates, and crystals. The chapters in this book are organized into three parts: Part One looks at the techniques used to measure protein-protein interactions and equilibrium protein phases in dilute and concentrated protein solutions; Part Two describes methods to measure kinetics of aggregation and to characterize the assembled state; and Part Three details several different computational approaches that are currently used to help researchers understand protein self-assembly. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Thorough and cutting-edge, Protein Self-Assembly: Methods and Protocols is a valuable resource for researchers who are interested in learning more about this developing field.

Protein Misfolding, Aggregation and Conformational Diseases

Protein Misfolding, Aggregation and Conformational Diseases
Author: Vladimir N. Uversky
Publisher: Springer Science & Business Media
Total Pages: 538
Release: 2007-05-26
Genre: Medical
ISBN: 0387365346

The second volume continues to fill the gap in protein review and protocol literature. It does this while summarizing recent achievements in the understanding of the relationships between protein misfoldings, aggregation, and development of protein deposition disorders. The focus of Part B is the molecular basis of differential disorders.

Protein Actions: Principles and Modeling

Protein Actions: Principles and Modeling
Author: Ivet Bahar
Publisher: Garland Science
Total Pages: 337
Release: 2017-02-14
Genre: Science
ISBN: 1351815016

Protein Actions: Principles and Modeling is aimed at graduates, advanced undergraduates, and any professional who seeks an introduction to the biological, chemical, and physical properties of proteins. Broadly accessible to biophysicists and biochemists, it will be particularly useful to student and professional structural biologists and molecular biophysicists, bioinformaticians and computational biologists, biological chemists (particularly drug designers) and molecular bioengineers. The book begins by introducing the basic principles of protein structure and function. Some readers will be familiar with aspects of this, but the authors build up a more quantitative approach than their competitors. Emphasizing concepts and theory rather than experimental techniques, the book shows how proteins can be analyzed using the disciplines of elementary statistical mechanics, energetics, and kinetics. These chapters illuminate how proteins attain biologically active states and the properties of those states. The book ends with a synopsis the roles of computational biology and bioinformatics in protein science.