Current Catalog

Current Catalog
Author: National Library of Medicine (U.S.)
Publisher:
Total Pages: 1732
Release:
Genre: Medicine
ISBN:

First multi-year cumulation covers six years: 1965-70.

Plasma Fractionation and Blood Transfusion

Plasma Fractionation and Blood Transfusion
Author: C.Th. Smit Sibinga
Publisher: Springer Science & Business Media
Total Pages: 239
Release: 2012-12-06
Genre: Medical
ISBN: 1461326311

Plasma fractionation and blood transfusion are inherently linked. Blood bankers need to have a sincere interest in fractionation and purification techniques in order to understand the need for carefully controlled source material collection and initial processing. Developments point to a shift in technology, implementation and application of plasma fractions to be produced, such that early anticipation from both bloodbankers and fractionators in a joint interest and effort are needed. As usual there is good news and bad news. We are referring in that respect to the exciting presentation about the future of bloodbanking. Although the blood donor still plays a major role in bloodbanking, new technologies could terminate the conventional blood transfusion service in the next 20-40 years. Sooner or later DNA technology will play an important role in bloodbanking and bloodbankers will have to deal with cultivated red cells as a replacement of our donor blood. Several fractionation techniques like column chromatography, controlled pore glass chromatography, heparin double cold precipitation technology and polyelectrolite fractionation are available, which may result in better yields for some of the plasma proteins. These techniques are likely to replace in part the old Cohn fractionation in the near future.

Protein Purification Process Engineering

Protein Purification Process Engineering
Author: Roger Harrison
Publisher: Routledge
Total Pages: 398
Release: 2019-07-16
Genre: Medical
ISBN: 1351421018

Offers coverage of the development of protein purification processes for large-scale commercial operations, and addresses process development, scale-up, applications and mathematical descriptions. Technologies currently used at the commercial scale are covered in depth.

Protides of the Biological Fluids

Protides of the Biological Fluids
Author: H. Peeters
Publisher: Elsevier
Total Pages: 926
Release: 2014-05-20
Genre: Science
ISBN: 1483158357

Protides of the Biological Fluids reviews trends in research concerning protides of the biological fluids, with emphasis on tumor-associated antigens (TAAs), lectins, and separation methods such as electrophoresis and isoelectric focusing. Examples of TAAs discussed in this book are carcinoembryonic antigens, mesenchyme-associated antigens, and oncofetal pancreatic antigens. The mode of action of lectins as well as lectin-binding sites are also considered. This book is comprised of 195 chapters and begins with an overview of the strategy and monitoring of protein fractionation, followed by a discussion on the self-nonself concept of cancer and ""autoimmune"" diseases; presence of trophoblast antigens on the membranes of some human tumor and transformed cells; and non-specific cross-reacting antigens in human blood monocytes. Subsequent chapters explore the metabolism of carcinoembryonic antigen and alpha-fetoprotein during delivery; amino acid sequence identity of tissue polypeptide antigen fragments from different sources; isoferritins, glycoproteins, and viral antigens; and crossed immunoelectrophoresis of yeast plasma membrane lectin receptors. The final section is devoted to separation techniques such as isotachophoresis, chromatography, electrophoresis, and isoelectric focusing. This monograph will be of value to biologists and researchers interested in protides of the biological fluids.