This is an open access book. We are now heading into the era of society 5.0. The era of society 5.0 was developed by Japanese Government to describe the integration between physical and virtual spaces that can solve social problems. Many things in this era are run based on the concept of internet-based big data technology that will make human life easier. The effect of this era will be felt in various aspects of our lives such as health, education, transportation, industry, etc. If we look at Indonesia specifically, Indonesia is currently still in the era of 4.0. It can be seen in various fields, one of them is education field. Education in Indonesia currently already uses online learning method. However, for the 5.0 era, online learning method will use various technology-based educational tools. For this reason, it is important for educators to not only use technology in teaching but also focus and put attention on student’s character, moral, and discipline. Although there are so many benefits and positive aspects we will feel in the era of 5.0, we also need to open our eyes to the negative aspects that may occur when students are exposed to too much technology. The opportunity to get the freedom to access the internet and unlimited access of information can have negative impact on students such as game and social media addiction, cyber bullying, etc. These problems can have an impact to student’s mental health as we can find in several studies which say that “internet addiction has a tendency to make a person apathetic, addicted, and PTSD. Mental health is important because this kind of health is related to many aspects in human such as physical and cognitive functions. One of interesting topics related to this issue is how human cognitive functions, especially about the brain and nervous system in addiction and mental health issues which we called neuroscience. For these reasons, an international seminar entitled " INTERNATIONAL CONFERENCE ON PSYCHOLOGY AND HEALTH ISSUES” carries the theme advancement in health science and psychology for society 5.0.