Brief Lives

Brief Lives
Author: John Aubrey
Publisher: Franklin Classics Trade Press
Total Pages: 404
Release: 2018-10-25
Genre:
ISBN: 9780344183744

This work has been selected by scholars as being culturally important and is part of the knowledge base of civilization as we know it. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. To ensure a quality reading experience, this work has been proofread and republished using a format that seamlessly blends the original graphical elements with text in an easy-to-read typeface. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.

Extremely Loud & Incredibly Close

Extremely Loud & Incredibly Close
Author: Jonathan Safran Foer
Publisher: Houghton Mifflin Harcourt
Total Pages: 372
Release: 2005
Genre: Fiction
ISBN: 9780618329700

Jonathan Safran Foer emerged as one of the most original writers of his generation with his best-selling debut novel, Everything Is Illuminated. Now, with humor, tenderness, and awe, he confronts the traumas of our recent history. What he discovers is solace in that most human quality, imagination. Meet Oskar Schell, an inventor, Francophile, tambourine player, Shakespearean actor, jeweler, pacifist, correspondent with Stephen Hawking and Ringo Starr. He is nine years old. And he is on an urgent, secret search through the five boroughs of New York. His mission is to find the lock that fits a mysterious key belonging to his father, who died in the World Trade Center on 9/11. An inspired innocent, Oskar is alternately endearing, exasperating, and hilarious as he careens from Central Park to Coney Island to Harlem on his search. Along the way he is always dreaming up inventions to keep those he loves safe from harm. What about a birdseed shirt to let you fly away? What if you could actually hear everyone's heartbeat? His goal is hopeful, but the past speaks a loud warning in stories of those who've lost loved ones before. As Oskar roams New York, he encounters a motley assortment of humanity who are all survivors in their own way. He befriends a 103-year-old war reporter, a tour guide who never leaves the Empire State Building, and lovers enraptured or scorned. Ultimately, Oskar ends his journey where it began, at his father's grave. But now he is accompanied by the silent stranger who has been renting the spare room of his grandmother's apartment. They are there to dig up his father's empty coffin.

The Toxicant Induction of Irritant Asthma, Rhinitis, and Related Conditions

The Toxicant Induction of Irritant Asthma, Rhinitis, and Related Conditions
Author: William J. Meggs
Publisher: Springer Science & Business Media
Total Pages: 297
Release: 2014-01-24
Genre: Medical
ISBN: 1461490448

Untoward reactions to environmental chemicals, particularly when a subject reports difficulties with exposures to chemicals of diverse classes involving more than one organ system, have been poorly understood and an area of great controversy. Studies of airway inflammation induced by respiratory irritants have established neurogenic inflammation as the mechanism for irritant asthma and rhinitis. Remodeling of the airway after an acute irritant exposure can lead to a heightened sensitivity to irritants that persists. Recognition that rhinitis, while sometimes regarded as a trivial disease, is associated with extra-airway manifestations such as fatigue and disturbances of sleep, mood, and cognition, further elucidates how chemical exposures can be serious for susceptible individuals. This book reviews current scientific understanding of irritant airway inflammation and related conditions, including cardiovascular effects of particulate exposures, airborne contact dermatitis and irritant dermatitis, and the brain as a target organ for both allergic and irritant reactions. It is essential reading for physicians and other healthcare workers caring for patients with environmental intolerances. Allergists, toxicologists, occupational and environmental physicians, and pulmonologists will find the materials particularly valuable. Patients and advocates for those with chemical intolerances will also find the book of interest.

Marine Niche: Applications in Pharmaceutical Sciences

Marine Niche: Applications in Pharmaceutical Sciences
Author: Neelam M Nathani
Publisher: Springer Nature
Total Pages: 454
Release: 2020-11-09
Genre: Medical
ISBN: 9811550174

This book offers a comprehensive study of biological molecules acquired from marine organisms, which have been exploited for drug discovery with the aim to treat human diseases. Biomolecules have potential impacts on a diverse range of fields, including medical and pharmaceutical science, industrial science, biotechnology, basic research, molecular science, environmental science and climate change, etc. To understand and effectively apply medicinally important biomolecules, multidisciplinary approaches are called for. The ocean remains a rich biological resource, and the vast untapped potential of novel molecules from marine bio-resources has caught the interest of more and more researchers. These novel biological compounds have never been found in terrestrial or other ecosystems, but only in this rich niche. Advances in sampling techniques and technologies, along with increased funding for research and nature conservation, have now encouraged scientists to look deeper in the waters. Aquaculture supports both tremendous seafood production and the bulk production of marine-derived drugs. Furthermore, molecular methods are now being extensively employed to explore the untapped marine microbial diversity. With the help of molecular and biotech tools, the ability of marine organisms to produce new biosynthetic drugs can be greatly enhanced. This book provides an extensive compilation of the latest information on marine resources and their undisputedly vital role in the treatment of diverse ailments.

Aqueous Polymeric Coatings for Pharmaceutical Dosage Forms

Aqueous Polymeric Coatings for Pharmaceutical Dosage Forms
Author: Linda A. Felton
Publisher: CRC Press
Total Pages: 668
Release: 2016-09-19
Genre: Medical
ISBN: 1315352923

Aqueous-based film coating has become routine in the pharmaceutical industry. This process eliminates the use of organic solvents and thus avoids economic, environmental, and toxicological issues related to residual solvents and solvent recovery. Aqueous-based coating, however, is complex and many variables may impact the final product and its performance. This fourth edition of Aqueous Polymeric Coatings for Pharmaceutical Dosage Forms aims to provide insight into the factors and parameters that should be considered and controlled for the successful development and commercialization of a coated product. The fourth edition has been revised and expanded to reflect the most recent scientific advancements from the literature. The contributing authors explain in detail, using illustrated examples, appropriate steps to solve and ideally avoid formulation, processing, and stability problems and to achieve an optimized dosage form. Trade names and chemical names of commercially marketed coatings are used throughout the text to help familiarize the reader with the various materials available for pharmaceutical applications. This book will be a valuable resource for anyone in the pharmaceutical industry working in the area of aqueous-based film coating.