PRINCIPLES OF MEDICINAL CHEMISTRY Vol. - II
| Author | : Dr. S. S. Kadam |
| Publisher | : Pragati Books Pvt. Ltd. |
| Total Pages | : 484 |
| Release | : 2007-07 |
| Genre | : |
| ISBN | : 9788185790039 |
Principles Of Medicinal Chemistry Vol Ii
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Principles of Medicinal Chemistry Volume-I
| Author | : Dr. S. S. Kadam |
| Publisher | : Pragati Books Pvt. Ltd. |
| Total Pages | : 616 |
| Release | : 2013-05 |
| Genre | : Study Aids |
| ISBN | : 9788185790046 |
1.General Principles2. Topical Anti-Infective Agents3.Chemotherapy of Parasitic Diseases 4.Sulphonamides and Urinary Tract Antiseptic gents 5.Antibiotics 6.Modes of Action of Antibiotics 7.Antifungal Agents 8.Antiviral Agents 9.Anti-Neoplastic Agents 10.Anti-Tuberculosis and Anti-Leprotic Agents 11.Hormones 12.Insulin and Oral Hypoglycemic Agents 13.Diuretics 14.Drugs Acting on Blood 15.Drugs Acting on GIT 16.Drugs Acting on Respiratory Tract 17.Diagnostic Agents 18.Immuno-Modulators 19.Adverse Effects 20.Quantitative Structure Activity Relationship 21.Vitamins Synthesis of Drugs (Appendix) Index
Quantum Medicinal Chemistry
| Author | : Paolo Carloni |
| Publisher | : John Wiley & Sons |
| Total Pages | : 294 |
| Release | : 2006-03-06 |
| Genre | : Science |
| ISBN | : 3527605304 |
Computational methods are transforming the work of chemical and pharmaceutical laboratories. Increasingly faster and more exact simulation algorithms have made quantum chemistry a valuable tool in the search for active substances. Written by a team of leading international quantum chemists, this book is aimed at both beginners as well as experienced users of quantum chemical methods. All commonly used quantum chemical methods are treated here, including Density Functional Theory, quantum and molecular mechanical approaches. Numerous examples illustrate the use of these methods for dealing with problems in pharmaceutical practice, whether the study of inhibitor binding, identifying the surface load of active substances or deriving molecular descriptors using quantum chemical tools. For anyone striving to stay ahead in this rapidly evolving field.
Foye's Principles of Medicinal Chemistry
| Author | : Thomas L. Lemke |
| Publisher | : Lippincott Williams & Wilkins |
| Total Pages | : 1521 |
| Release | : 2012-01-24 |
| Genre | : Medical |
| ISBN | : 1609133455 |
Acclaimed by students and instructors alike, Foye's Principles of Medicinal Chemistry is now in its Seventh Edition, featuring updated chapters plus new material that meets the needs of today's medicinal chemistry courses. This latest edition offers an unparalleled presentation of drug discovery and pharmacodynamic agents, integrating principles of medicinal chemistry with pharmacology, pharmacokinetics, and clinical pharmacy. All the chapters have been written by an international team of respected researchers and academicians. Careful editing ensures thoroughness, a consistent style and format, and easy navigation throughout the text.
Foye's Principles of Medicinal Chemistry
| Author | : David A. Williams |
| Publisher | : Lippincott Williams & Wilkins |
| Total Pages | : 1136 |
| Release | : 2002 |
| Genre | : Medical |
| ISBN | : 0683307371 |
This comprehensive Fifth Edition has been fully revised and updated to meet the changing curricula of medicinal chemistry courses. The new emphasis is on pharmaceutical care that focuses on the patient, and on the pharmacist a therapeutic clinical consultant, rather than chemist. Approximately 45 contributors, respected in the field of pharmacy education, augment this exhaustive reference. New to this edition are chapters with standardized formats and features, such as Case Studies, Therapeutic Actions, Drug Interactions, and more. Over 700 illustrations supplement this must-have resource.
Natural Products in Medicinal Chemistry
| Author | : Stephen Hanessian |
| Publisher | : John Wiley & Sons |
| Total Pages | : 652 |
| Release | : 2013-12-18 |
| Genre | : Medical |
| ISBN | : 3527676554 |
The inspiration provided by biologically active natural products to conceive of hybrids, congeners, analogs and unnatural variants is discussed by experts in the field in 16 highly informative chapters. Using well-documented studies over the past decade, this timely monograph demonstrates the current importance and future potential of natural products as starting points for the development of new drugs with improved properties over their progenitors. The examples are chosen so as to represent a wide range of natural products with therapeutic relevance among others, as anticancer agents, antimicrobials, antifungals, antisense nucleosides, antidiabetics, and analgesics. From the content: * Part I: Natural Products as Sources of Potential Drugs and Systematic Compound Collections * Part II: From Marketed Drugs to Designed Analogs and Clinical Candidates * Part III: Natural Products as an Incentive for Enabling Technologies * Part IV: Natural Products as Pharmacological Tools * Part V: Nature: The Provider, the Enticer, and the Healer
The Handbook of Medicinal Chemistry
| Author | : Andrew Davis |
| Publisher | : Royal Society of Chemistry |
| Total Pages | : 789 |
| Release | : 2015-07-07 |
| Genre | : Science |
| ISBN | : 1782621830 |
Drug discovery is a constantly developing and expanding area of research. Developed to provide a comprehensive guide, the Handbook of Medicinal Chemistry covers the past, present and future of the entire drug development process. Highlighting the recent successes and failures in drug discovery, the book helps readers to understand the factors governing modern drug discovery from the initial concept through to a marketed medicine. With chapters covering a wide range of topics from drug discovery processes and optimization, development of synthetic routes, pharmaceutical properties and computational biology, the handbook aims to enable medicinal chemists to apply their academic understanding to every aspect of drug discovery. Each chapter includes expert advice to not only provide a rigorous understanding of the principles being discussed, but to provide useful hints and tips gained from within the pharmaceutical industry. This expertise, combined with project case studies, highlighting and discussing all areas of successful projects, make this an essential handbook for all those involved in pharmaceutical development.
The Practice of Medicinal Chemistry
| Author | : Camille Georges Wermuth |
| Publisher | : Elsevier |
| Total Pages | : 903 |
| Release | : 2015-07-01 |
| Genre | : Science |
| ISBN | : 012417213X |
The Practice of Medicinal Chemistry, Fourth Edition provides a practical and comprehensive overview of the daily issues facing pharmaceutical researchers and chemists. In addition to its thorough treatment of basic medicinal chemistry principles, this updated edition has been revised to provide new and expanded coverage of the latest technologies and approaches in drug discovery.With topics like high content screening, scoring, docking, binding free energy calculations, polypharmacology, QSAR, chemical collections and databases, and much more, this book is the go-to reference for all academic and pharmaceutical researchers who need a complete understanding of medicinal chemistry and its application to drug discovery and development. - Includes updated and expanded material on systems biology, chemogenomics, computer-aided drug design, and other important recent advances in the field - Incorporates extensive color figures, case studies, and practical examples to help users gain a further understanding of key concepts - Provides high-quality content in a comprehensive manner, including contributions from international chapter authors to illustrate the global nature of medicinal chemistry and drug development research - An image bank is available for instructors at www.textbooks.elsevier.com
Chemometric Methods in Molecular Design, Volume 2
| Author | : Han van de Waterbeemd |
| Publisher | : Wiley-VCH |
| Total Pages | : 388 |
| Release | : 1995-02-22 |
| Genre | : Health & Fitness |
| ISBN | : |
Edited by R. Mannhold, P. Krogsgaard-Larsen, H. Timmerman Chemometric Methods in Molecular Design Edited by Han van de Waterbeemd Volume 2 The statistical analysis of experimental and theoretical data lies at the heart of modern drug design. This practice-oriented handbook is a comprehensive account of modern chemometric methods in molecular design. It presents strategies for making more rational choices in the planning of syntheses, and describes techniques for analyzing biological and chemical data. Written by the world's experts, it provides in-depth information on molecular concepts experimental design in the planning of syntheses multivariate analysis of chemical and biological data statistical validation of QSAR results An additional benefit: the book contains a critical survey of commercially available software packages both for statistical analysis as well as for special applications. Industrial and academic researches in medicinal chemistry and organic chemistry will value this book as a useful source of information for their daily work. Also available: Advanced Computer-Assisted Techniques in Drug Discovery, edited by H. van de Waterbeemd.
Basic Concepts in Medicinal Chemistry
| Author | : Marc Harrold |
| Publisher | : ASHP |
| Total Pages | : 405 |
| Release | : 2013-01-18 |
| Genre | : Medical |
| ISBN | : 1585283649 |
Medicinal chemistry is a complex topic. Written in an easy to follow and conversational style, Basic Concepts in Medicinal Chemistry focuses on the fundamental concepts that govern the discipline of medicinal chemistry as well as how and why these concepts are essential to therapeutic decisions. The book emphasizes functional group analysis and the basics of drug structure evaluation. In a systematic fashion, learn how to identify and evaluate the functional groups that comprise the structure of a drug molecule and their influences on solubility, absorption, acid/base character, binding interactions, and stereochemical orientation. Relevant Phase I and Phase II metabolic transformations are also discussed for each functional group. Key features include: • Discussions on the roles and characteristics of organic functional groups, including the identification of acidic and basic functional groups. • How to solve problems involving pH, pKa, and ionization; salts and solubility; drug binding interactions; stereochemistry; and drug metabolism. • Numerous examples and expanded discussions for complex concepts. • Therapeutic examples that link the importance of medicinal chemistry to pharmacy and healthcare practice. • An overview of structure activity relationships (SARs) and concepts that govern drug design. • Review questions and practice problems at the end of each chapter that allow readers to test their understanding, with the answers provided in an appendix. Whether you are just starting your education toward a career in a healthcare field or need to brush up on your organic chemistry concepts, this book is here to help you navigate medicinal chemistry. About the Authors Marc W. Harrold, BS, Pharm, PhD, is Professor of Medicinal Chemistry at the Mylan School of Pharmacy, Duquesne University, Pittsburgh, PA. Professor Harrold is the 2011 winner of the Omicron Delta Kappa "Teacher of the Year" award at Duquesne University. He is also the two-time winner of the "TOPS" (Teacher of the Pharmacy School) award at the Mylan School of Pharmacy. Robin M. Zavod, PhD, is Associate Professor for Pharmaceutical Sciences at the Chicago College of Pharmacy, Midwestern University, Downers Grove, IL, where she was awarded the 2012 Outstanding Faculty of the Year award. Professor Zavod also serves on the adjunct faculty for Elmhurst College and the Illinois Institute of Technology. She currently serves as Editor-in-Chief of the journal Currents in Pharmacy Teaching and Learning.
