Principles of Animal Research for Graduate and Undergraduate Students

Principles of Animal Research for Graduate and Undergraduate Students
Author: Mark A. Suckow
Publisher: Academic Press
Total Pages: 288
Release: 2016-11-16
Genre: Psychology
ISBN: 012802366X

Principles of Animal Research is the first publication to offer a broad look at animal research science for a student, early researcher, or technician. Offering guidance for all aspects of the research experience, including the research and development of a thesis, model selection, experimental design, IACUC protocol preparation, and animal husbandry and technical procedural needs, the book is a necessary addition to every student, technician, and researcher’s education. Provides background material for students to understand the broader backdrop against which animal research is undertaken Includes ethical and regulatory information Covers commonly used animal models and the process to choose a model for biomedical research

Principles of Animal Research Ethics

Principles of Animal Research Ethics
Author: Tom L. Beauchamp
Publisher: Oxford University Press, USA
Total Pages: 177
Release: 2020-01-30
Genre: Medical
ISBN: 0190939125

This volume is the first to present a framework of general principles for animal research ethics together with an analysis of the principles' meaning and moral requirements. This new framework of six moral principles constitutes a more suitable set of moral guidelines than any currently available, including the influential framework presented in the Principles of Humane Experimental Technique published in 1959 by zoologist and psychologist William M. S. Russell and microbiologist Rex L. Burch. While other accounts have presented specific directives to guide the use of animals in research, Tom L. Beauchamp and David DeGrazia here offer a set of general moral principles that are adequate to the task of evaluating biomedical and behavioral research involving animals today. Their comprehensive framework addresses ethical requirements pertaining to societal benefit-a critical consideration in justifying the harming of animals in research-and features a thorough program of animal welfare protection. In doing so, their principles bridge the gap between the concerns of the research community and the animal-protection community. The book is distinctive in featuring commentaries on the framework of principles by eminent figures in animal research ethics from an array of relevant disciplines: veterinary medicine, biomedical research, biology, zoology, comparative psychology, primatology, law, and bioethics. The seven commentators-Larry Carbone, Frans de Waal, Rebecca Dresser, Joseph Garner, Brian Hare, Margaret Landi, and Julian Savulescu-scrutinize Beauchamp and DeGrazia's principles in terms of both their theoretical cogency and practical implications, evaluating their relevance to the medical and scientific professions. The range of ethical issues encompassed in Principles of Animal Research Ethics will be useful to professionals in the biomedical and behavioral sciences and will also appeal to individuals and scholars interested in bioethics, animal ethics, and applied ethics generally.

Essentials of Laboratory Animal Science: Principles and Practices

Essentials of Laboratory Animal Science: Principles and Practices
Author: P. Nagarajan
Publisher: Springer Nature
Total Pages: 797
Release: 2021-07-23
Genre: Science
ISBN: 981160987X

This book comprehensively reviews the anatomy, physiology, genetics and pathology of laboratory animals as well as the principles and practices of using laboratory animals for biomedical research.It covers the design of buildings used for laboratory animals, quality control of laboratory animals, and toxicology, and discusses various animal models used for human diseases. It also highlights aspects, such as handling and restraint and administration of drugs, as well as breeding and feeding of laboratory animals, and provides guidelines for developing meaningful experiments using laboratory animals.Further, the book discusses various alternatives to animal experiments for drug and chemical testing, including their advantages over the current approaches. Lastly, it examines the potential effect of harmful pathogens on the physiology of laboratory animals and discusses the state of art in in vivo imaging techniques.The book is a useful resource for research scientists, laboratory animal veterinarians, and students of laboratory animal medicine.

Education and Training in the Care and Use of Laboratory Animals

Education and Training in the Care and Use of Laboratory Animals
Author: National Research Council
Publisher: National Academies Press
Total Pages: 152
Release: 1991-02-01
Genre: Science
ISBN: 0309043824

Federal law now requires that institutions provide training for anyone caring for or using laboratory animals. This volume provides the guidelines and resources needed to coordinate a quality training program, as well as to meet all legal requirements. A core module for all personnel takes no more than four hours to present. Most staff then proceed to one or more additional skills-development modules including the species-specific module that can be customized to any species in use at the institution, the pain management module, and the surgery module. The volume provides content information for required topics-from ethics to record keeping-and lists sources of additional publications, audiovisual programs, and computerized teaching aids. Included are: Ready-to-use teaching outlines, with detailed instructions for presenting material. Practical guidelines on logistics, covering scheduling, budgeting, and more. Guidelines on how to design training for adults and how to work with investigators who may resist taking training courses. This practical guidebook will be necessary for research institutions, particularly for staff members responsible for training coordination.

Molecular and Quantitative Animal Genetics

Molecular and Quantitative Animal Genetics
Author: Hasan Khatib
Publisher: John Wiley & Sons
Total Pages: 336
Release: 2015-03-02
Genre: Science
ISBN: 1118677404

Animal genetics is a foundational discipline in the fields of animal science, animal breeding, and veterinary sciences. While genetics underpins the healthy development and breeding of all living organisms, this is especially true in domestic animals, specifically with respect to breeding for key traits. Molecular and Quantitative Animal Genetics is a new textbook that takes an innovative approach, looking at both quantitative and molecular breeding approaches. The bookprovides a comprehensive introduction to genetic principles and their applications in animal breeding. This text provides a useful overview for those new to the field of animal genetics and breeding, covering a diverse array of topics ranging from population and quantitative genetics to epigenetics and biotechnology. Molecular and Quantitative Animal Genetics will be an important and invaluable educational resource for undergraduate and graduate students and animal agriculture professionals. Divided into six sections pairing fundamental principles with useful applications, the book's comprehensive coverage will make it an ideal fit for students studying animal breeding and genetics at any level.

Handbook of Laboratory Animal Science

Handbook of Laboratory Animal Science
Author: Jann Hau
Publisher: CRC Press
Total Pages: 0
Release: 2021
Genre: Medical
ISBN: 9780429801587

Building upon the success of previous editions of the bestselling Handbook of Laboratory Animal Science, first published in 1994, this latest revision combines all three volumes in one definitive guide. It covers the essential principles and practices of Laboratory Animal Science as well as selected animal models in scientific disciplines where much progress has been made in recent years. Each individual chapter focuses on an important subdiscipline of laboratory animal science, and the chapters can be read and used as stand-alone texts, with only limited necessity to consult other chapters for information. With new contributors at the forefront of their fields, the book reflects the scientific and technological advances of the past decade. It also responds to advances in our understanding of animal behavior, emphasizing the importance of implementing the three Rs: replacing live animals with alternative methods, reducing the number of animals used, and refining techniques to minimize animal discomfort. This fourth edition will be useful all over the world as a textbook for laboratory animal science courses for postgraduate and undergraduate students and as a handbook for scientists who work with animals in their research, for university veterinarians, and for other specialists in laboratory animal science.

Essentials for Animal Research

Essentials for Animal Research
Author: B. Taylor Bennett
Publisher: DIANE Publishing
Total Pages: 100
Release: 1996-12
Genre:
ISBN: 9780788136351

Includes a basic understanding of the regulatory process & the means by which compliance can be assured; an understanding of the basic principles of controlling pain & distress, preventing intraoperative infection, & assuring a humane death in the animals used; & an awareness of the responsibilities one assumes when choosing to use lab. animals. Contents: regulations & requirements; alternative methodologies; animal care & use; principles of anesthesia, analgesia, & aseptic technique; perioperative care; euthanasia; organizations, associations, & societies; & references.

Applied Ethics in Animal Research

Applied Ethics in Animal Research
Author: John P. Gluck
Publisher: Purdue University Press
Total Pages: 216
Release: 2002
Genre: Medical
ISBN: 9781557531360

This volume is a collection of chapters all contributed by individuals who have presented their ideas at conferences and who take moderate stands with the use of animals in research. Specifically the chapters bear of the issues of: notions of the moral standings of animals, history of the methods of argumentation, knowledge of the animal mind, nature and value of regulatory structures, how respect for animals can be converted from theory to action in the laboratory. The chapters have been tempered by open discussion with individuals with different opinions and not audiences of true believers. It is the hope of all, that careful consideration of the positions in these chapters will leave reader with a deepened understanding--not necessarily a hardened position.

International Animal Research Regulations

International Animal Research Regulations
Author: National Research Council
Publisher: National Academies Press
Total Pages: 102
Release: 2012-06-26
Genre: Science
ISBN: 0309252113

Animals are widely used in neuroscience research to explore biological mechanisms of nervous system function, to identify the genetic basis of disease states, and to provide models of human disorders and diseases for the development of new treatments. To ensure the humane care and use of animals, numerous laws, policies, and regulations are in place governing the use of animals in research, and certain animal regulations have implications specific to neuroscience research. To consider animal research regulations from a global perspective, the IOM Forum on Neuroscience and Nervous System Disorders, in collaboration with the National Research Council and the Institute for Laboratory Animal Research, held a workshop in Buckinghamshire, UK, July 26-27, 2011. The workshop brought together neuroscientists, legal scholars, administrators, and other key stakeholders to discuss current and emerging trends in animal regulations as they apply to the neurosciences. This document summarizes the workshop.

Guide for the Care and Use of Laboratory Animals

Guide for the Care and Use of Laboratory Animals
Author: National Research Council
Publisher: National Academies Press
Total Pages: 246
Release: 2011-01-27
Genre: Science
ISBN: 0309154006

A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.