Principles And Practice Of Systematic Reviews And Meta Analysis
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| Author | : Sanjay Patole |
| Publisher | : Springer |
| Total Pages | : 188 |
| Release | : 2021-08-03 |
| Genre | : Medical |
| ISBN | : 9783030719203 |
Evidence based medicine is at the core of modern medicine. It involves the integration of individual clinical expertise with the best available clinical evidence from systematic research and patient's values and expectations. Systematic reviews offer a summary of the best available evidence. They are the most reliable and comprehensive statement about what works. Written by clinical academics from Australia, UK, USA, and Switzerland, this contributed volume introduces the readers to the principles and practice of systematic reviews and meta-analysis. It covers the various steps involved in systematic reviews including development of a focused question and the strategy for conducting a comprehensive literature search, identifying studies addressing the underlying question, assessment of heterogeneity and the risk of bias in the included studies, data extraction, and the approach to meta-analysis. Crucial issues such as selecting the model for meta-analysis, generating and interpreting forest plots, assessing the risk of publication bias, cautions in the interpretation of subgroup and sensitivity analyses, rating certainty of the evidence using GRADE guideline, and standardized reporting of meta-analysis (PRISMA) are covered in detail. Every attempt is made to keep the narrative simple and clear. Mathematical formulae are avoided as much as possible. While the focus of this book is on systematic reviews and meta-analyses of randomised controlled trials (RCTs), the gold standard of clinical research, the essentials of systematic reviews of non-RCTs, diagnostic test accuracy studies, animal studies, individual participant data meta-analysis, and network meta-analysis are also covered. Readers from all faculties of medicine will enjoy this comprehensive and reader friendly book to understand the principles and practice of systematic reviews and meta-analysis for guiding their clinical practice and research.
| Author | : Matthias Egger |
| Publisher | : John Wiley & Sons |
| Total Pages | : 512 |
| Release | : 2008-04-15 |
| Genre | : Medical |
| ISBN | : 0470693142 |
The second edition of this best-selling book has been thoroughly revised and expanded to reflect the significant changes and advances made in systematic reviewing. New features include discussion on the rationale, meta-analyses of prognostic and diagnostic studies and software, and the use of systematic reviews in practice.
| Author | : Institute of Medicine |
| Publisher | : National Academies Press |
| Total Pages | : 267 |
| Release | : 2011-07-20 |
| Genre | : Medical |
| ISBN | : 0309164257 |
Healthcare decision makers in search of reliable information that compares health interventions increasingly turn to systematic reviews for the best summary of the evidence. Systematic reviews identify, select, assess, and synthesize the findings of similar but separate studies, and can help clarify what is known and not known about the potential benefits and harms of drugs, devices, and other healthcare services. Systematic reviews can be helpful for clinicians who want to integrate research findings into their daily practices, for patients to make well-informed choices about their own care, for professional medical societies and other organizations that develop clinical practice guidelines. Too often systematic reviews are of uncertain or poor quality. There are no universally accepted standards for developing systematic reviews leading to variability in how conflicts of interest and biases are handled, how evidence is appraised, and the overall scientific rigor of the process. In Finding What Works in Health Care the Institute of Medicine (IOM) recommends 21 standards for developing high-quality systematic reviews of comparative effectiveness research. The standards address the entire systematic review process from the initial steps of formulating the topic and building the review team to producing a detailed final report that synthesizes what the evidence shows and where knowledge gaps remain. Finding What Works in Health Care also proposes a framework for improving the quality of the science underpinning systematic reviews. This book will serve as a vital resource for both sponsors and producers of systematic reviews of comparative effectiveness research.
| Author | : Julian P. T. Higgins |
| Publisher | : Wiley |
| Total Pages | : 672 |
| Release | : 2008-11-24 |
| Genre | : Medical |
| ISBN | : 9780470699515 |
Healthcare providers, consumers, researchers and policy makers are inundated with unmanageable amounts of information, including evidence from healthcare research. It has become impossible for all to have the time and resources to find, appraise and interpret this evidence and incorporate it into healthcare decisions. Cochrane Reviews respond to this challenge by identifying, appraising and synthesizing research-based evidence and presenting it in a standardized format, published in The Cochrane Library (www.thecochranelibrary.com). The Cochrane Handbook for Systematic Reviews of Interventions contains methodological guidance for the preparation and maintenance of Cochrane intervention reviews. Written in a clear and accessible format, it is the essential manual for all those preparing, maintaining and reading Cochrane reviews. Many of the principles and methods described here are appropriate for systematic reviews applied to other types of research and to systematic reviews of interventions undertaken by others. It is hoped therefore that this book will be invaluable to all those who want to understand the role of systematic reviews, critically appraise published reviews or perform reviews themselves.
| Author | : Sanjay Patole |
| Publisher | : Springer Nature |
| Total Pages | : 189 |
| Release | : 2021-06-26 |
| Genre | : Medical |
| ISBN | : 3030719219 |
Evidence based medicine is at the core of modern medicine. It involves the integration of individual clinical expertise with the best available clinical evidence from systematic research and patient's values and expectations. Systematic reviews offer a summary of the best available evidence. They are the most reliable and comprehensive statement about what works. Written by clinical academics from Australia, UK, USA, and Switzerland, this contributed volume introduces the readers to the principles and practice of systematic reviews and meta-analysis. It covers the various steps involved in systematic reviews including development of a focused question and the strategy for conducting a comprehensive literature search, identifying studies addressing the underlying question, assessment of heterogeneity and the risk of bias in the included studies, data extraction, and the approach to meta-analysis. Crucial issues such as selecting the model for meta-analysis, generating and interpreting forest plots, assessing the risk of publication bias, cautions in the interpretation of subgroup and sensitivity analyses, rating certainty of the evidence using GRADE guideline, and standardized reporting of meta-analysis (PRISMA) are covered in detail. Every attempt is made to keep the narrative simple and clear. Mathematical formulae are avoided as much as possible. While the focus of this book is on systematic reviews and meta-analyses of randomised controlled trials (RCTs), the gold standard of clinical research, the essentials of systematic reviews of non-RCTs, diagnostic test accuracy studies, animal studies, individual participant data meta-analysis, and network meta-analysis are also covered. Readers from all faculties of medicine will enjoy this comprehensive and reader friendly book to understand the principles and practice of systematic reviews and meta-analysis for guiding their clinical practice and research.
| Author | : Jacqueline Corcoran |
| Publisher | : Oxford University Press |
| Total Pages | : 211 |
| Release | : 2008-02-13 |
| Genre | : Social Science |
| ISBN | : 0199716862 |
When used in tandem, systematic reviews and meta-analysis-- two distinct but highly compatible approaches to research synthesis-- form a powerful, scientific approach to analyzing previous studies. But to see their full potential, a social work researcher must be versed in the foundational processes underlying them. This pocket guide to Systematic Reviews and Meta-Analysis illuminates precisely that practical groundwork. In clear, step-by-step terms, the authors explain how to format topics, locate and screen studies, extract and assess data, pool effect sizes, determine bias, and interpret the results, showing readers how to combine reviewing and meta-analysis correctly and effectively. Each chapter contains vivid social work examples and concludes with a concise summary and notes on further reading, while the book's glossary and handy checklists and sample search and data extraction forms maximize the boo'ks usefulness. Highlighting the concepts necessary to understand, critique, and conduct research synthesis, this brief and highly readable introduction is a terrific resource for students and researchers alike.
| Author | : Heidi D. Nelson |
| Publisher | : Lippincott Williams & Wilkins |
| Total Pages | : 313 |
| Release | : 2024-02-21 |
| Genre | : Medical |
| ISBN | : 1975211103 |
Accessible, practical, and student-friendly, Systematic Reviews to Answer Health Care Questions, Second Edition, by Dr. Heidi D. Nelson, uses easy-to-understand, step-by-step instruction and real-world examples to illustrate important concepts and principles of today’s systematic reviews. You’ll learn how to form key questions, select evidence, and perform comprehensive reviews not just in predictable circumstances, but when basic rules don’t apply—honing your ability to think critically and solve problems. Perfect for investigators, medical students and faculty, practitioners, policymakers, and others who need to refine their understanding of or approach to systematic reviews, this powerful text goes beyond merely teaching how to catalog and collect, helping readers learn to evaluate, synthesize, and deliver results that will help shape the practice of health care.
| Author | : Julia H. Littell |
| Publisher | : Oxford University Press |
| Total Pages | : 211 |
| Release | : 2008-02-13 |
| Genre | : Medical |
| ISBN | : 0195326547 |
When used in tandem, systematic reviews and meta-analysis-- two distinct but highly compatible approaches to research synthesis-- form a powerful, scientific approach to analyzing previous studies. But to see their full potential, a social work researcher must be versed in the foundational processes underlying them. This pocket guide to Systematic Reviews and Meta-Analysis illuminates precisely that practical groundwork.In clear, step-by-step terms, the authors explain how to format topics, locate and screen studies, extract and assess data, pool effect sizes, determine bias, and interpret the results, showing readers how to combine reviewing and meta-analysis correctly and effectively. Each chapter contains vivid social work examples and concludes with a concise summary and notes on further reading, while the book's glossary and handy checklists and sample search and data extraction forms maximize the boo'ks usefulness.Highlighting the concepts necessary to understand, critique, and conduct research synthesis, this brief and highly readable introduction is a terrific resource for students and researchers alike.
| Author | : Matthias Egger |
| Publisher | : John Wiley & Sons |
| Total Pages | : 612 |
| Release | : 2022-06-21 |
| Genre | : Medical |
| ISBN | : 1405160500 |
Systematic Reviews in Health Research Explore the cutting-edge of systematic reviews in healthcare In this Third Edition of the classic Systematic Reviews textbook, now titled Systematic Reviews in Health Research, a team of distinguished researchers deliver a comprehensive and authoritative guide to the rapidly evolving area of systematic reviews and meta-analysis. The book demonstrates why systematic reviews—when conducted properly—provide the highest quality evidence on clinical and public health interventions and shows how they contribute to inference in many other contexts. The new edition reflects the broad role of systematic reviews, including: Twelve new chapters, covering additional study designs, methods and software, for example, on genetic association studies, prediction models, prevalence studies, network and dose-response meta-analysis Thorough update of 15 chapters focusing on systematic reviews of interventions Access to a companion website offering supplementary materials and practical exercises (www.systematic-reviews3.org) A key text for health researchers, Systematic Reviews in Health Research is also an indispensable resource for practitioners, students, and instructors in the health sciences needing to understand research synthesis.
| Author | : Christine Webb |
| Publisher | : John Wiley & Sons |
| Total Pages | : 280 |
| Release | : 2008-04-15 |
| Genre | : Medical |
| ISBN | : 0470691417 |
Reviewing research evidence for nursing practice: systematic reviews highlights the key issues involved in conducting different types of systematic reviews - encompassing qualitative studies, quantitative studies and combining quantitative and qualitative studies. It enables nurses and researchers to understand the key principles involved in preparing systematic reviews and to critically appraise the reviews they read and evaluate their usefulness in developing their own practice. Each section starts with an overview of the methodology, followed by a selection of systematic reviews carried out in specialist areas of nursing practice. Part 1 explores systematic reviews and meta-analysis of quantitative research, part 2 explores meta-synthesis and meta-study of qualitative research and part 3 addresses integrative reviews that combine both qualitative and quantitative evidence. The final part explores the use of systematic reviews in service and practice development.
