Predictive Evaluation

Predictive Evaluation
Author: David Basarab
Publisher: Berrett-Koehler Publishers
Total Pages: 169
Release: 2010-12-13
Genre: Business & Economics
ISBN: 1605098574

At last, an answer to the question that has bedeviled trainers for decades. Predictive evaluation enables you to effectively and accurately forecast training's value to your company, measure against these predictions, establish indicators to track your progress, make midcourse corrections, and report the results in a language that business executives respond to and understand. Dave Basarab explains how to begin by identifying the specific goals and beliefs you want to instill in participants. The next step is to determine exactly what these will look like when put into action. Finally you develop quantifiable measures of how employees' adopting the target beliefs and goals will impact the business. A key strength of this process is that it is profoundly collaborative—supervisors and employees work together to establish standards for success each step of the way. A how-to guide filled with worksheets, examples, and other tools, Predictive Evaluation ensures that, rather than being regarded as an expense and an act of faith, training will be seen as an investment with a concrete payoff.

Predictive Evaluation

Predictive Evaluation
Author: Donald Kirkpatrick
Publisher: ReadHowYouWant.com
Total Pages: 258
Release: 2011-08-18
Genre: Business & Economics
ISBN: 1459626338

This work supports a process called Predictive Evaluation (PE) which enables practitioners to provide executives with compelling training data around the success of training in the three areas of Intention, Adoption, and Impact. PEalso works to determine whether success has been achieved, and provides lead indicators of future adoption (transfer...

Applications of Toxicogenomic Technologies to Predictive Toxicology and Risk Assessment

Applications of Toxicogenomic Technologies to Predictive Toxicology and Risk Assessment
Author: National Research Council
Publisher: National Academies Press
Total Pages: 300
Release: 2007-12-19
Genre: Science
ISBN: 0309112982

The new field of toxicogenomics presents a potentially powerful set of tools to better understand the health effects of exposures to toxicants in the environment. At the request of the National Institute of Environmental Health Sciences, the National Research Council assembled a committee to identify the benefits of toxicogenomics, the challenges to achieving them, and potential approaches to overcoming such challenges. The report concludes that realizing the potential of toxicogenomics to improve public health decisions will require a concerted effort to generate data, make use of existing data, and study data in new waysâ€"an effort requiring funding, interagency coordination, and data management strategies.

The Future of Predictive Safety Evaluation

The Future of Predictive Safety Evaluation
Author: D.V. Parke
Publisher: Springer Science & Business Media
Total Pages: 226
Release: 2012-12-06
Genre: Medical
ISBN: 9400941390

A. N. WORDEN, D. V. PARKE AND J. MARKS THE BACKGROUND There is nothing new about the fact that chemical substances derived either from natural products or by synthetic means .. can give rise to toxicity in animals and human beings, and that they must be subjected to controls. The earliest writings speak of such toxicity and, from the times of ancient Egypt and in the Old Tes tament, controls have existed[l]. In the Middle Ages Paracelsus (1493-1541) noted that "All things are poisons, for there is nothing without poisonous qualities. It is only the dose which makes a thing a poison", and hence he stressed the importance of dose relative to toxic reactions [ 2] . Most of the early controls concentrated on substances that were to be deliberately administered to the human subject in the form of medicines. Legislation for many centuries was mainly con cerned with regulating the activities of apothecaries and physicians. The Royal College of Physicians, for example, was originally established to control the activities of physicians within London. Among the controls which it exerted was that over the use of medicinal substances. Such controls were, however, poor, based as they were on hearsay evidence of toxicity. For many centuries no means existed for the accurate determination of toxicity.

Optimized Predictive Models in Health Care Using Machine Learning

Optimized Predictive Models in Health Care Using Machine Learning
Author: Sandeep Kumar
Publisher: John Wiley & Sons
Total Pages: 388
Release: 2024-02-08
Genre: Computers
ISBN: 1394175353

OPTIMIZED PREDICTIVE MODELS IN HEALTH CARE USING MACHINE LEARNING This book is a comprehensive guide to developing and implementing optimized predictive models in healthcare using machine learning and is a required resource for researchers, healthcare professionals, and students who wish to know more about real-time applications. The book focuses on how humans and computers interact to ever-increasing levels of complexity and simplicity and provides content on the theory of optimized predictive model design, evaluation, and user diversity. Predictive modeling, a field of machine learning, has emerged as a powerful tool in healthcare for identifying high-risk patients, predicting disease progression, and optimizing treatment plans. By leveraging data from various sources, predictive models can help healthcare providers make informed decisions, resulting in better patient outcomes and reduced costs. Other essential features of the book include: provides detailed guidance on data collection and preprocessing, emphasizing the importance of collecting accurate and reliable data; explains how to transform raw data into meaningful features that can be used to improve the accuracy of predictive models; gives a detailed overview of machine learning algorithms for predictive modeling in healthcare, discussing the pros and cons of different algorithms and how to choose the best one for a specific application; emphasizes validating and evaluating predictive models; provides a comprehensive overview of validation and evaluation techniques and how to evaluate the performance of predictive models using a range of metrics; discusses the challenges and limitations of predictive modeling in healthcare; highlights the ethical and legal considerations that must be considered when developing predictive models and the potential biases that can arise in those models. Audience The book will be read by a wide range of professionals who are involved in healthcare, data science, and machine learning.

Predictive ADMET

Predictive ADMET
Author: Jianling Wang
Publisher: John Wiley & Sons
Total Pages: 604
Release: 2014-02-28
Genre: Medical
ISBN: 1118783409

This book helps readers integrate in silico, in vitro, and in vivo ADMET (absorption, distribution, metabolism, elimination and toxicity) and PK (pharmacokinetics) data with routine testing applications so that pharmaceutical scientists can diagnose ADMET problems and present appropriate recommendations to move drug discovery programs forward. The book introduces the current clinical practice for drug discovery and development along with the impact on early risk assessment; consolidates the tools and models to intelligently integrate existing in silico, in vitro and in vivo ADMET data; and demonstrates successful cases and lessons learned from real drug discovery and development. In short, it is a book aimed to provide a practical road map for drug discovery and development scientists to generate efficacious and safe drugs for unmet medical needs.

Predictive Analytics

Predictive Analytics
Author: Eric Siegel
Publisher: John Wiley & Sons
Total Pages: 336
Release: 2013-02-19
Genre: Business & Economics
ISBN: 1118356853

In this rich, entertaining primer, former Columbia University professor and Predictive Analytics World founder Eric Siegel reveals the power and perils of prediction: What type of mortgage risk Chase Bank predicted before the recession. Predicting which people will drop out of school, cancel a subscription, or get divorced before they are even aware of it themselves. Why early retirement decreases life expectancy and vegetarians miss fewer flights. Five reasons why organizations predict death, including one health insurance company. A truly omnipresent science, predictive analytics affects everyone, every day. Although largely unseen, it drives millions of decisions, determining whom to call, mail, investigate, incarcerate, set up on a date, or medicate. Predictive analytics transcends human perception. This book's final chapter answers the riddle: What often happens to you that cannot be witnessed, and that you can't even be sure has happened afterward -- but that can be predicted in advance? Whether you are a consumer of it -- or consumed by it -- get a handle on the power of Predictive Analytics. This book is easily understood by all readers. Rather than a "how to" for hands-on techies, the book entices lay-readers and experts alike by covering new case studies and the latest state-of-the-art techniques.

Toxicogenomics in Predictive Carcinogenicity

Toxicogenomics in Predictive Carcinogenicity
Author: Russell S Thomas
Publisher: Royal Society of Chemistry
Total Pages: 524
Release: 2016-06-16
Genre: Medical
ISBN: 1782624058

Research over the past decade has demonstrated that TGx methods of various types can be used to discriminate modes of mutagenesis as a function of dose. TGx can quickly inform safety evaluation regarding potential mechanisms of conventional outcomes and can provide essential dose-response information. This can then be used to ascertain the sequence of key events in a putative mode of action as may apply in quantitative cancer risk assessment. With the increasing complexity of research in mode of action investigations it is important to gain a better understand of approaches to data integration and health risk assessment. Furthermore, it is essential to consider how novel test systems and newer methods and approaches may be used in future to gain a better understanding of mechanisms. Toxicogenomics in Predictive Carcinogenicity describes toxicogenomics methods in predictive carcinogenicity testing, mode of action and safety evaluation, and cancer risk assessment. It illustrates these methods using case studies that have yielded significant new information on compounds and classes of compounds that have proven difficult to evaluate using conventional methods alone. This book additionally covers current and potential toxicogenomic research using stem cells as well as new bioinformatics methods for drug discovery and environmental toxicology. This publication is an indispensable tool for postgraduates, academics and industrialists working in biochemistry, genomics, carcinogenesis, pathology, pharmaceuticals, food technology, bioinformatics, risk assessment and environmental toxicology.

Teaching Materials and the Roles of EFL/ESL Teachers

Teaching Materials and the Roles of EFL/ESL Teachers
Author: Ian McGrath
Publisher: Bloomsbury Publishing
Total Pages: 257
Release: 2013-03-14
Genre: Language Arts & Disciplines
ISBN: 1441194924

Teaching Materials and the Roles of EFL/ESL Teachers is published amidst a decade long increase in academic publications and training courses concerned with the evaluation and design of English language teaching materials. It is timely to consider what effect the advice on offer has had on teachers' practice. Are teachers evaluating materials carefully, using textbooks in the ways expected by textbook writers, developing their own materials, and mediating between materials and learners in the ways advised in the professional literature? The book explores these issues from a variety of perspectives. The views of publishers/textbook writers, those contributing to the professional literature, and teacher educators are synthesised to establish a 'theory' of how teachers can best fulfil their roles vis-à-vis materials and learners. This is then compared with 'practice', as represented by published accounts of teachers' actual practices and learners' perspectives. The conclusion reached is that teacher education in materials evaluation and design is essential and suggestions are offered as to the form this might take. The book is intended particularly for MA students and teacher educators concerned with materials evaluation and design, but is of interest to all those concerned with the publication and use of English language teaching materials.

Big Data in Predictive Toxicology

Big Data in Predictive Toxicology
Author: Daniel Neagu
Publisher: Royal Society of Chemistry
Total Pages: 303
Release: 2019-12-04
Genre: Medical
ISBN: 1839160829

The rate at which toxicological data is generated is continually becoming more rapid and the volume of data generated is growing dramatically. This is due in part to advances in software solutions and cheminformatics approaches which increase the availability of open data from chemical, biological and toxicological and high throughput screening resources. However, the amplified pace and capacity of data generation achieved by these novel techniques presents challenges for organising and analysing data output. Big Data in Predictive Toxicology discusses these challenges as well as the opportunities of new techniques encountered in data science. It addresses the nature of toxicological big data, their storage, analysis and interpretation. It also details how these data can be applied in toxicity prediction, modelling and risk assessment. This title is of particular relevance to researchers and postgraduates working and studying in the fields of computational methods, applied and physical chemistry, cheminformatics, biological sciences, predictive toxicology and safety and hazard assessment.