Polymeric Nanosystems

Polymeric Nanosystems
Author: Md Saquib Hasnain
Publisher: Academic Press
Total Pages: 909
Release: 2023-03-23
Genre: Medical
ISBN: 0323885772

Polymeric Nanosystems: Theranostic Nanosystems, Volume One examines the applications of nanotherapeutic systems and nanodiagnostics in relation to polymeric nanosystems. In the last decade, numerous biopolymers have been utilized to prepare polymeric nanosystems for therapeutic applications. These biopolymers include polylactic acid, polylactide-co-glycolide, polycaprolactone, acrylic polymers, cellulose and cellulose derivatives, alginates, chitosan, gellan gum, gelatin, albumin, chontroitin sulfate, hyaluronic acid, guar gum, gum Arabic, gum tragacanth, xanthan gum, and starches. Besides these biopolymers, grafted polymers are also being used as advanced polymeric materials to prepare many theranostic nanocarriers and nanoformulations. This book explores the array of polymeric nanosystems to understand therapeutic potentials. It will be useful to pharmaceutical scientists, including industrial pharmacists and analytical scientists, health care professionals, and regulatory scientists actively involved in the pharmaceutical product and process development of tailor-made polysaccharides in drug delivery applications. - Contains in-depth discussions of the polymeric nanosystems including high-quality graphics, flowcharts, and graphs for enhanced understanding - Reviews the literature on polymeric nanosystems while also suggesting new avenues - Includes contributions in all areas of polymeric nanosystems, providing a thorough and interdisciplinary work

Polymeric Nanomaterials in Nanotherapeutics

Polymeric Nanomaterials in Nanotherapeutics
Author:
Publisher: Elsevier
Total Pages: 561
Release: 2018-10-26
Genre: Science
ISBN: 0128139331

Polymeric Nanomaterials in Nanotherapeutics describes how polymeric nanosensors and nanorobotics are used for biomedical instrumentation, surgery, diagnosis and targeted drug delivery for cancer, pharmacokinetics, monitoring of diabetes and healthcare. Key areas of coverage include drug administration and formulations for targeted delivery and release of active agents (drug molecules) to non-healthy tissues and cells. The book demonstrates how these are applied to dental work, wound healing, cancer, cardiovascular diseases, neurodegenerative disorders, infectious diseases, chronic inflammatory diseases, metabolic diseases, and more. Methods of administration discussed include oral, dental, topical and transdermal, pulmonary and nasal, ocular, vaginal, and brain drug delivery and targeting. Drug delivery topics treated in several subchapters includes materials for active targeting and cases study of polymeric nanomaterials in clinical trials. The toxicity and regulatory status of therapeutic polymeric nanomaterials are also examined. The book gives a broad perspective on the topic for researchers, postgraduate students and professionals in the biomaterials, biotechnology, and biomedical fields. - Shows how the properties of polymeric nanomaterials can be used to create more efficient medical treatments/therapies - Demonstrates the potential and range of applications of polymeric nanomaterials in disease prevention, diagnosis, drug development, and for improving treatment outcomes - Accurately explains how nanotherapeutics can help in solving problems in the field through the latest technologies and formulations

Polymer and Polymer-Hybrid Nanoparticles

Polymer and Polymer-Hybrid Nanoparticles
Author: Stanislav Rangelov
Publisher: CRC Press
Total Pages: 504
Release: 2013-08-28
Genre: Science
ISBN: 1439869073

Polymeric and hybrid nanoparticles have received increased scientific interest in terms of basic research as well as commercial applications, promising a variety of uses for nanostructures in fields including bionanotechnology and medicine. Condensing the relevant research into a comprehensive reference, Polymer and Polymer-Hybrid Nanoparticles: From Synthesis to Biomedical Applications covers an array of topics from synthetic procedures and macromolecular design to possible biomedical applications of nanoparticles and materials based on original and unique polymers. The book presents a well-rounded picture of objects ranging from simple polymeric micelles to complex hybrid polymer-based nanostructures, detailing synthetic procedures, techniques for characterization and analysis, properties, and behavior in selective solvents and dispersions. Each chapter contains background and introductory information, summarizing generalities on the nanosystems being discussed. The chapters also describe representative works of experts and provide in-depth, focused discussions. The authors present current knowledge on the following topics: Designed synthesis of functional polymers Construction of block copolymer micellar and nonmicellar self-assembled structures Construction of organic–organic hybrid nanosized particles Construction of organic–inorganic hybrid nanoparticles and nanoassemblies The final chapter addresses biological applications of polymeric nanoparticles, including delivery of low-molecular-weight drugs, macromolecular drugs, imaging and diagnostics, and photodynamic therapy. Summarizing important developments in the field, the authors condense relevant research into a comprehensive resource.

Polymeric Nanoparticles for Bovine Mastitis Treatment

Polymeric Nanoparticles for Bovine Mastitis Treatment
Author: Ali Haider
Publisher: Springer Nature
Total Pages: 157
Release: 2023-09-22
Genre: Science
ISBN: 3031399471

This book features an in-depth examination of the ongoing problem of bovine mastitis and the potential solutions offered by polymer nanoparticles. With extensive research and analysis, the book delves into the causes and consequences of bovine mastitis, including the shift in the relevance of various infections and the increasing problem of antibiotic resistance. The authors explore the use of nanoparticles as a potential alternative to traditional antibiotics and the importance of tailoring their characteristics for specific uses. Detailed discussions of the pros and cons of different manufacturing procedures and characterizations of bovine mastitis, drug-resistant bacteria, and resistance development make this monograph an invaluable resource for researchers and experts in the field of veterinary medicine, and an excellent resource for those interested in investigating the viability of nano-materials as future antibiotic alternatives.

Smart Polymeric Nano-Constructs in Drug Delivery

Smart Polymeric Nano-Constructs in Drug Delivery
Author: Suresh P Vyas
Publisher: Academic Press
Total Pages: 626
Release: 2022-11-12
Genre: Medical
ISBN: 0323913997

Smart Polymeric Nano-Constructs in Drug Delivery: Concept, Design and Therapeutic Applications provides a thorough discussion of the most state of the art material and polymer exploitations for the delivery of bioactive(s) as well as their current and clinical status. The book enables researchers to prepare a variety of smart drug delivery systems to investigate their properties as well as to discover their uses and applications. The novelty of this approach addresses an existing need of exhaustively understanding the potential of the materials including polymeric drug delivery systems that are smartly designed to deliver bioactive(s) into the body at targeted sites without showing side effects. The book is helpful for those in the health sector, specifically those developing nanomedicine using smart material-based nano-delivery systems. Polymers have unique co-operative properties that are not found with low-molecular-weight compounds along with their appealing physical and chemical properties, constituting the root of their success in drug delivery. Smart Polymeric Nano-Constructs in Drug Delivery: Concept, Design and Therapeutic Applications discusses smart and stimuli responsive polymers applicable in drug delivery, followed detailed information about various concepts and designing of polymeric novel drug delivery systems for treatment of various type of diseases, also discussing patents related to the field. The book helps readers to design and develop novel drug delivery systems based on smart materials for the effective delivery of bioactive that take advantage of recent advances in smart polymer-based strategies. It is useful to those in pharmaceutical sciences and related fields in developing new drug delivery systems. - Provides comprehensive overview of the potential role of polymeric systems in drug delivery - Explores the design, synthesis, and application of different smart material-based delivery systems - Includes fundamental and clinical applications

Nanoparticles in Polymer Systems for Biomedical Applications

Nanoparticles in Polymer Systems for Biomedical Applications
Author: Jince Thomas
Publisher: CRC Press
Total Pages: 342
Release: 2018-12-12
Genre: Medical
ISBN: 1351047876

The volume includes presentations of technological and research accomplishments along with novel approaches in nanomedicine and nanotechnology. It explores the different types of nanomedicinal drugs with their production and commercial significance. Other topics discussed are the use of natural and synthetic nanoparticles for the production of drugs, different types of nanoparticles systems, drug carriers, wound-healing antimicrobial activity, effects of natural materials in nanomedicine, and toxicity of nanoparticles. The valuable information presented in this volume will help to keep those in this field up to date on the key findings, observations, and fabrication of drugs related to nanomedicine and nanotechnology. With chapters written by prominent researchers from academia, industry, and government and private research laboratories across the world, the book will prove to be a rich resource.

Organic Materials as Smart Nanocarriers for Drug Delivery

Organic Materials as Smart Nanocarriers for Drug Delivery
Author: Alexandru Mihai Grumezescu
Publisher: William Andrew
Total Pages: 770
Release: 2018-03-26
Genre: Science
ISBN: 0128136642

Organic Materials as Smart Nanocarriers for Drug Delivery presents the latest developments in the area of organic frameworks used in pharmaceutical nanotechnology. An up-to-date overview of organic smart nanocarriers is explored, along with the different types of nanocarriers, including polymeric micelles, cyclodextrins, hydrogels, lipid nanoparticles and nanoemlusions. Written by a diverse range of international academics, this book is a valuable reference for researchers in biomaterials, the pharmaceutical industry, and those who want to learn more about the current applications of organic smart nanocarriers. - Explores the most recent molecular- and structure-based applications of organic smart nanocarriers in drug delivery - Highlights different smart nanocarriers and assesses their intricate organic structural properties for improving drug delivery - Assesses how molecular organic frameworks lead to more effective drug delivery systems

Drug Delivery Nanosystems for Biomedical Applications

Drug Delivery Nanosystems for Biomedical Applications
Author: Chandra P. Sharma
Publisher: Elsevier
Total Pages: 454
Release: 2018-08-22
Genre: Technology & Engineering
ISBN: 0323509231

Drug Delivery Nanosystems for Biomedical Application reviews some of the most challenging nanosystems with different routes of delivery that are useful for specific drugs, from both efficacy and bioavailability points-of-view. The chapters explore how this area is developing, the present state of the field, and future developments, in particular, inorganic, metallic, polymeric, composite and lipid nanosystems and their possible evolution to clinical applications. The book is a valuable research reference for both researchers and industrial partners who are not only interested in learning about this area, but also want to gain insights on how to move towards translational research. - Focuses on applications, including tissue engineering and regenerative technologies, showing how nanosystems are used in practice - Explores how nanosystems are used to deliver a variety of drugs, including peptides, hormone growth factors and genes - Assesses the safety and nanotoxicity aspects of drug delivery nanosystems

Block Co-polymeric Nanocarriers: Design, Concept, and Therapeutic Applications

Block Co-polymeric Nanocarriers: Design, Concept, and Therapeutic Applications
Author: Neeraj Mishra
Publisher: Springer Nature
Total Pages: 440
Release: 2023-11-29
Genre: Medical
ISBN: 9819969174

This book focuses on current advancements in the field of block copolymers and covers design, concept, and various therapeutic applications in the drug delivery. It also reviews the use of block copolymers in drug delivery applications from the development of sustained release products to smart polymeric delivery systems such as stimuli-responsive polymeric systems, for example, thermosensitive, redox-sensitive, photo-sensitive, and enzyme-sensitive. The book further discusses the nano assemblies from amphiphilic block copolymers as nanomedicine platforms for diagnosis and therapy due to their relatively small size, high drug loading capacity, controlled drug release, in vivo stability, and prolonged blood circulation. The chapters also review the various patents and ongoing clinical trials on the applications, covering several important new concepts and findings in the field of block copolymers. The book is aimed at researchers, academicians, and industrial scientists involved in the development of drug-delivery systems based on polymers.

Nanoparticles for Therapeutic Applications

Nanoparticles for Therapeutic Applications
Author: Madhuri Sharon
Publisher: John Wiley & Sons
Total Pages: 596
Release: 2022-07-13
Genre: Science
ISBN: 1119762308

NANOPARTICLES FOR THERAPEUTIC APPLICATIONS The main goal of this book is to provide information on theranostic applications of various nanomaterials for different diseases with self-explanatory illustrations and fundamental descriptions of a plethora of properties of molecular traits. The author has written a fascinating book on research topics and fundamentals in the cross-disciplinary area of nanotechnology and bioscience in which she successfully fuses otherwise divergent research topics of this rapidly emerging area. The book deals with the use of nanomaterials for combatting various diseases and disorders of the human body. The three chapters of the first part of this book deal with the areas in which nanotechnology has contributed to nanomedicine. In the second part, different disorders like cancer, neurodegenerative diseases, genetic diseases, infectious diseases, cardiovascular disorders, eye, dentistry, bone, and cartilage-affecting diseases are discussed. In the chapters related to a disease or disorder of a particular organ, a basic brief introduction to them is given as well. Audience The book will be read by researchers, scientists, and graduate students in biotechnology, nanotechnology, materials science, and nanomedicine/biomedicine.