Adverse Events Associated with Childhood Vaccines

Adverse Events Associated with Childhood Vaccines
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 481
Release: 1993-01-01
Genre: Medical
ISBN: 0309048958

Childhood immunization is one of the major public health measures of the 20th century and is now receiving special attention from the Clinton administration. At the same time, some parents and health professionals are questioning the safety of vaccines because of the occurrence of rare adverse events after immunization. This volume provides the most thorough literature review available about links between common childhood vaccinesâ€"tetanus, diphtheria, measles, mumps, polio, Haemophilus influenzae b, and hepatitis Bâ€"and specific types of disorders or death. The authors discuss approaches to evidence and causality and examine the consequencesâ€"neurologic and immunologic disorders and deathâ€"linked with immunization. Discussion also includes background information on the development of the vaccines and details about the case reports, clinical trials, and other evidence associating each vaccine with specific disorders. This comprehensive volume will be an important resource to anyone concerned about the immunization controversy: public health officials, pediatricians, attorneys, researchers, and parents.

Immunization Safety Review

Immunization Safety Review
Author: Institute of Medicine
Publisher: National Academies Press
Total Pages: 118
Release: 2003-12-26
Genre: Medical
ISBN: 0309086108

The Immunization Safety Review Committee was established by the Institute of Medicine (IOM) to evaluate the evidence on possible causal associations between immunizations and certain adverse outcomes, and to then present conclusions and recommendations. The committee's mandate also includes assessing the broader societal significance of these immunization safety issues. While all the committee members share the view that immunization is generally beneficial, none of them has a vested interest in the specific immunization safety issues that come before the group. The committee reviews three immunization safety review topics each year, addressing each one at a time. In this fifth report in a series, the committee examines the hypothesis that exposure to polio vaccine contaminated with simian virus 40 (SV40), a virus that causes inapparent infection in some monkeys, can cause certain types of cancer.

Polio

Polio
Author: Thomas Abraham
Publisher: Oxford University Press
Total Pages: 350
Release: 2018-09-01
Genre: Medical
ISBN: 1787380874

In 1988, the World Health Organization launched a twelve-year campaign to wipe out polio. Thirty years and several billion dollars over budget later, the campaign grinds on, vaccinating millions of children and hoping that each new year might see an end to the disease. But success remains elusive, against a surprisingly resilient virus, an unexpectedly weak vaccine and the vagaries of global politics, meeting with indifference from governments and populations alike. How did an innocuous campaign to rid the world of a crippling disease become a hostage of geopolitics? Why do parents refuse to vaccinate their children against polio? And why have poorly paid door-to-door healthworkers been assassinated? Thomas Abraham reports on the ground in search of answers.

The Cutter Incident

The Cutter Incident
Author: Paul A. Offit
Publisher: Yale University Press
Total Pages: 262
Release: 2007-09-18
Genre: History
ISBN: 9780300126051

Vaccines have saved more lives than any other single medical advance. Yet today only four companies make vaccines, and there is a growing crisis in vaccine availability. Why has this happened? This remarkable book recounts for the first time a devastating episode in 1955 at Cutter Laboratories in Berkeley, California, thathas led many pharmaceutical companies to abandon vaccine manufacture. Drawing on interviews with public health officials, pharmaceutical company executives, attorneys, Cutter employees, and victims of the vaccine, as well as on previously unavailable archives, Dr. Paul Offit offers a full account of the Cutter disaster. He describes the nation's relief when the polio vaccine was developed by Jonas Salk in 1955, the production of the vaccine at industrial facilities such as the one operated by Cutter, and the tragedy that occurred when 200,000 people were inadvertently injected with live virulent polio virus: 70,000 became ill, 200 were permanently paralyzed, and 10 died. Dr. Offit also explores how, as a consequence of the tragedy, one jury's verdict set in motion events that eventually suppressed the production of vaccines already licensed and deterred the development of new vaccines that hold the promise of preventing other fatal diseases.

The Polio Pioneer

The Polio Pioneer
Author: Linda Elovitz Marshall
Publisher: Knopf Books for Young Readers
Total Pages: 40
Release: 2020-08-18
Genre: Juvenile Nonfiction
ISBN: 0525646531

A SYDNEY TAYLOR NOTABLE BOOK • Learn about the importance of vaccines and the scientific process through the fascinating life of world-renowned scientist Jonas Salk, whose pioneering discoveries changed the world forever. Dr. Jonas Salk is one of the most celebrated doctors and medical researchers of the 20th century. The child of immigrants who never learned to speak English, Jonas was struck by the devastation he saw when the soldiers returned from battle after WWII. Determined to help, he worked to become a doctor and eventually joined the team that created the influenza vaccine. But Jonas wanted to do more. As polio ravaged the United States--even the president was not immune!--Jonas decided to lead the fight against this terrible disease. In 1952, Dr. Jonas Salk invented the polio vaccine, which nearly eliminated polio from this country. For the rest of his life, Dr. Salk continued to do groundbreaking medical research at the Salk Institute, leaving behind a legacy that continues to make the world a better place every day. This compelling picture book biography sheds light on Dr. Salk's groundbreaking journey and the importance of vaccination.

Canadian Immunization Guide

Canadian Immunization Guide
Author: Canada. Comité consultatif national de l'immunisation
Publisher:
Total Pages: 392
Release: 2006
Genre: Immunization
ISBN: 9780660193922

The seventh edition of the Canadian Immunization Guide was developed by the National Advisory Committee on Immunization (NACI), with the support ofthe Immunization and Respiratory Infections Division, Public Health Agency of Canada, to provide updated information and recommendations on the use of vaccines in Canada. The Public Health Agency of Canada conducted a survey in 2004, which confi rmed that the Canadian Immunization Guide is a very useful and reliable resource of information on immunization.

Trial by Fury

Trial by Fury
Author: Aaron E. Klein
Publisher:
Total Pages: 216
Release: 1972
Genre: Medical
ISBN:

Vaccines

Vaccines
Author: Stanley A. Plotkin
Publisher: Elsevier Health Sciences
Total Pages: 1748
Release: 2008-02-11
Genre: Medical
ISBN: 1437721583

Completely revised and updated, this respected reference offers comprehensive and current coverage of every aspect of vaccination-from development to use in reducing disease. It provides authoritative information on vaccine production, available preparations, efficacy, and safety...recommendations for vaccine use, with rationales...data on the impact of vaccination programs on morbidity and mortality...and more. And now, as an Expert Consult title, it includes a companion web site offering this unparalleled guidance where and when you need it most! Provides a complete understanding of each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, as well an epidemiology and public health issues. Offers comprehensive coverage of both existing vaccines and vaccines currently in the research and development stage. Examines vaccine stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease control strategies. Analyses the cost-benefit and cost-effectiveness of vaccines. Discusses the proper use of immune globulins and antitoxins. Illustrates concepts and objective data with approximately 600 tables and figures. Includes access to a companion web site offering the complete contents of the book - fully searchable - for rapid consultation from anyplace with an Internet connection.

Vaccines: The Biggest Medical Fraud in History

Vaccines: The Biggest Medical Fraud in History
Author: Trung Nguyen
Publisher: EnCognitive.com
Total Pages: 668
Release: 2021-10-23
Genre: Medical
ISBN: 1927091578

NEW COVID-19 CHAPTER! "Polio is NOT even contagious or infectious (never proven to be). There is NO proof Polio is caused by a virus. There is NO evidence that anyone caught polio from another person in the family. There is NO evidence that any nurse or doctor caught polio from a patient." —Sheri Nakken, RN, MA Listed below are public health statistics (U.S. Public Health Reports) from the four states which adopted compulsory vaccination, and the figures from Los Angeles, California (similar results in other states available from books listed at the back of this booklet): TENNESSEE 1958: 119 cases of polio before compulsory shots 1959: 386 cases of polio after compulsory shots OHIO 1958: 17 cases of polio before compulsory shots 1959: 52 cases of polio after compulsory shots CONNECTICUT 1958: 45 cases of polio before compulsory shots 1959: 123 cases of polio after compulsory shots NORTH CAROLINA 1958: 78 cases of polio before compulsory shots 1959: 313 cases of polio after compulsory shots LOS ANGELES 1958: 89 cases of polio before shots 1959: 190 cases of polio after shots The decline of smallpox, as with many other infectious diseases, including diphtheria and scarlet fever, coincided with the sanitation reforms which were instituted in the late 1880s. Where obtainable, government health records from around the world showed that during the periods of the most intense and widespread vaccination, the incidence of and death rates from smallpox were highest. For instance, in Kansas City and Pittsburgh during the 1920s, lawsuits were initiated, and won, against doctors and medical societies for declaring smallpox epidemics when there were none, and for creating epidemics with their vaccination drives. Before 1903, smallpox was almost unknown in the Philippines, with occurrences in less than 3% of the population, and that in a mild form. The U.S. military went in and began vaccinating, and by 1905 the Philippines had its first major epidemic. Vaccination was made compulsory in 1910. From 1905 to 1923, the mortality rate ranged from 25-75%, depending on the count from the various islands. “The mortality rate was the highest in the cities where vaccination was most intense.” Dr. W.W. Keen reported 130,264 cases and 74,369 deaths from smallpox in 1921. Japan adopted compulsory vaccinations in 1872 when they had only a few cases of smallpox. By 1892 they had the largest smallpox epidemic in their history with 165,774 cases and 29,979 deaths. Australia banned the smallpox vaccine after some children were killed by it, and in the following 15 years in unvaccinated Australia there were only 3 cases of smallpox. The smallpox vaccine was discontinued in the United States after Dr. Henry Kempe reported to Congress in 1966 that fewer people were dying from the disease than from vaccination.