PET Chemistry

PET Chemistry
Author: P.A. Schubiger
Publisher: Springer Science & Business Media
Total Pages: 348
Release: 2007-01-19
Genre: Science
ISBN: 3540495274

Personalized medicine employing patient-based tailor-made therapeutic drugs is taking over treatment paradigms in a variety of ?elds in oncology and the central nervous system. The success of such therapies is mainly dependent on ef?cacious therapeutic drugs and a selective imaging probe for identi?cation of potential responders as well as therapy monitoring for an early bene?t assessment. Molecular imaging (MI) is based on the selective and speci?c interaction of a molecular probe with a biological target which is visualized through nuclear, magnetic resonance, near infrared or other methods. Therefore it is the method of choice for patient selection and therapy monitoring as well as for speci?c e- point monitoring in modern drug development. PET (positron emitting tomography), a nuclear medical imaging modality, is ideally suited to produce three-dimensional images of various targets or processes. The rapidly increasing demand for highly selective probes for MI strongly pushes the development of new PET tracers and PET chemistry. ‘PET chemistry’ can be de?ned as the study of positron-emitting compounds regarding their synthesis, structure, composition, reactivity, nuclear properties and processes and their properties in natural and - natural environments. In practice PET chemistry is strongly in?uenced by the unique properties of the radioisotopes used (e. g. , half-life, che- cal reactivity, etc. ) and integrates scienti?c aspects of nuclear-, organic-, inorganic- and biochemistry.

Basics of PET Imaging

Basics of PET Imaging
Author: Gopal B. Saha
Publisher: Springer Science & Business Media
Total Pages: 244
Release: 2010-03-10
Genre: Medical
ISBN: 1441908056

This reference on the basics of PET and PET/CT imaging has been revised with concise chapters on PET fundamentals. The chapters include pertinent basic science plus equations along with sample problems and practice questions.

Polyethylene Terephthalate

Polyethylene Terephthalate
Author: Naomi A. Barber
Publisher:
Total Pages: 0
Release: 2017
Genre: Polyesters
ISBN: 9781536119916

Polyethylene terephthalate (PET) is an aliphatic-aromatic and semicrystalline thermoplastic polyester of prime commercial and industrial importance. Namely, PET is a very important industrial polymer due to its excellent properties such as processability, chemical resistance, high tensile impact strength, high thermal stability and clarity. Chapter One summarises the synthesis and physicochemical properties of PET. In Chapter Two, the authors review the frequency-dependent parameters of the PET substrate, developments of the flexible RF electronics on PET substrate, and the challenges and potentials of RF applications using flexible electronics fabricated on PET films. Chapter Three presents a background of the current state of knowledge with respect to PET recycling.

Recycling of Polyethylene Terephthalate Bottles

Recycling of Polyethylene Terephthalate Bottles
Author: Sabu Thomas
Publisher: William Andrew
Total Pages: 213
Release: 2018-10-29
Genre: Technology & Engineering
ISBN: 0323509673

Recycling of Polyethylene Terephthalate Bottles provides an overview of PET chemistry, highlighting the main degradation, depolymerization processes and pathways of PET, along with the applications of recycled monomers derived from PET waste. The latest methodologies of recycling and feedstock recovery are covered, providing critical foundational information. In addition, the book discusses a range of established methods of polymer recycling, with an emphasis on real world industrial case studies and the latest academic research. Users will find in-depth lifecycle and cost analysis of each waste management method, comparing the suitability and feasibility of each to support the decision -making process. Polyethylene Terephthalate (PET) is the most recycled plastic in the world, but still represents a significant amount of landfill waste. This book presents an update on new regulations, providing recommendations for new opportunities in this area, including new processing methods and applications for recycled PET. - Features a comprehensive introduction to the waste management of PET bottles, from regulatory concerns, to the range of different methods of materials recovery - Enables practitioners to choose the most efficient and effective waste management process - Includes detailed lifecycle and cost analysis information - Compares traditional thermal recycling methods with more recently developed monomer recovery and chemical recycling methods

The Chemistry of Diamondoids

The Chemistry of Diamondoids
Author: Andrey A. Fokin
Publisher: John Wiley & Sons
Total Pages: 373
Release: 2024-04-17
Genre: Technology & Engineering
ISBN: 3527812938

The Chemistry of Diamondoids Comprehensive resource on an important and fascinating compound class, covering synthesis, properties, functionalization, and applications in organic synthesis, materials science, and more The Chemistry of Diamondoids gives a state-of-the-art overview of all aspects of diamondoid chemistry, covering nomenclature, natural occurrence, chemical and physical properties, along with synthesis and functionalization of diamondoids as well as their applications as molecular building blocks in organic synthesis, polymer and materials science, nanotechnology, and medicinal chemistry. The book concludes with a perspective towards future developments in the field, thereby drawing attention to areas open for discovery. Written by experts in the field, The Chemistry of Diamondoids includes information on: Naturally occurring diamondoids, their formation, and the role they play in the petroleum industry and in geosciences, plus man-made approaches to prepare them on large scale Growing diamond from diamondoids via seeding, preparation and properties of diamondoid oligomers and doped diamondoids C–H-bond functionalization, a precondition for their use in many applications, and fine-tuning of diamondoid properties by precise cage substitution reactions With its all-encompassing approach, The Chemistry of Diamondoids is a valuable guide for newcomers and researchers in organic chemistry and materials science interested in modern synthetic methods and organic functional materials.

Radiopharmaceutical Chemistry

Radiopharmaceutical Chemistry
Author: Jason S. Lewis
Publisher: Springer
Total Pages: 648
Release: 2019-04-02
Genre: Medical
ISBN: 3319989472

This book is a comprehensive guide to radiopharmaceutical chemistry. The stunning clinical successes of nuclear imaging and targeted radiotherapy have resulted in rapid growth in the field of radiopharmaceutical chemistry, an essential component of nuclear medicine and radiology. However, at this point, interest in the field outpaces the academic and educational infrastructure needed to train radiopharmaceutical chemists. For example, the vast majority of texts that address radiopharmaceutical chemistry do so only peripherally, focusing instead on nuclear chemistry (i.e. nuclear reactions in reactors), heavy element radiochemistry (i.e. the decomposition of radioactive waste), or solely on the clinical applications of radiopharmaceuticals (e.g. the use of PET tracers in oncology). This text fills that gap by focusing on the chemistry of radiopharmaceuticals, with key coverage of how that knowledge translates to the development of diagnostic and therapeutic radiopharmaceuticals for the clinic. The text is divided into three overarching sections: First Principles, Radiochemistry, and Special Topics. The first is a general overview covering fundamental and broad issues like “The Production of Radionuclides” and “Basics of Radiochemistry”. The second section is the main focus of the book. In this section, each chapter’s author will delve much deeper into the subject matter, covering both well established and state-of-the-art techniques in radiopharmaceutical chemistry. This section will be divided according to radionuclide and will include chapters on radiolabeling methods using all of the common nuclides employed in radiopharmaceuticals, including four chapters on the ubiquitously used fluorine-18 and a “Best of the Rest” chapter to cover emerging radionuclides. Finally, the third section of the book is dedicated to special topics with important information for radiochemists, including “Bioconjugation Methods,” “Click Chemistry in Radiochemistry”, and “Radiochemical Instrumentation.” This is an ideal educational guide for nuclear medicine physicians, radiologists, and radiopharmaceutical chemists, as well as residents and trainees in all of these areas.

Modern Polyesters

Modern Polyesters
Author: John Scheirs
Publisher: John Wiley & Sons
Total Pages: 784
Release: 2005-09-01
Genre: Technology & Engineering
ISBN: 0470090677

Provides an overview of the family of polyester polymers which comprise an important group of plastics that span the range of commodity polymers to engineering resins. It describes the preparation, properties and applications of polyesters. Readers will also find details on polyester-based elastomers, biodegradable aliphatic polyester, liquid crystal polyesters and unsaturated polyesters for glass-reinforced composites. Presents an overview of the most recent developments. Explores synthesis, catalysts, processes, properties and applications. Looks at emerging polyester materials as well as existing ones. Written by foremost experts from both academia and industry, ensuring that both fundamentals and practical applications are covered.

The Chemistry of Environmental Engineering

The Chemistry of Environmental Engineering
Author: Johannes Karl Fink
Publisher: John Wiley & Sons
Total Pages: 336
Release: 2020-04-07
Genre: Science
ISBN: 1119707749

The focus of this book is the chemistry of environmental engineering and its applications, with a special emphasis on the use of polymers in this field. It explores the creation and use of polymers with special properties such as viscoelasticity and interpenetrating networks; examples of which include the creation of polymer-modified asphalt as well as polymers with bacterial adhesion properties. The text contains the issues of polymerization methods, recycling methods, wastewater treatment, types of contaminants, such as microplastics, organic dyes, and pharmaceutical residues. After a detailed overview of polymers in Chapter 1, their special properties are discussed in the following chapter. Among the topics is the importance of polymers to water purification procedures, since their use in the formation of reverse osmosis membranes do not show biofouling. Chapter 3 details special processing methods, such as atom transfer radical polymerization, enzymatic polymerization, plasma treatment, and several other methods, can be used to meet the urgent demands of industrial applications. Chapter 4 addresses the important environmental issue of recycling methods as they relate to several types of materials such as PET bottles, tire rubbers, asphalt compositions, and other engineering resins. And wastewater treatment is detailed in Chapter 5, in which the types of contaminants, such as microplastics, organic dyes and pharmaceutical residues, are described and special methods for their proper removal are detailed along with types of adsorbents, including biosorbents. Still another important issue for environmental engineering chemistry is pesticides. Chapter 6 is a thorough description of the development and fabrication of special sensors for the detection of certain pesticides. A detailed presentation of the electrical uses of polymer-based composites is given in Chapter 7, which include photovoltaic materials, solar cells, energy storage and dielectric applications, light-emitting polymers, and fast-charging batteries. And recent issues relating to food engineering, such as food ingredient tracing, protein engineering, biosensors and electronic tongues, are presented in Chapter 8. Finally, polymers used for medical applications are described in Chapter 9. These applications include drug delivery, tissue engineering, porous coatings and also the special methods used to fabricate such materials.

Catalysis, Green Chemistry and Sustainable Energy

Catalysis, Green Chemistry and Sustainable Energy
Author: Angelo Basile
Publisher: Elsevier
Total Pages: 578
Release: 2019-11-22
Genre: Technology & Engineering
ISBN: 0444643389

Catalysis, Green Chemistry and Sustainable Energy: New Technologies for Novel Business Opportunities offers new possibilities for businesses who want to address the current global transition period to adopt low carbon and sustainable energy production. This comprehensive source provides an integrated view of new possibilities within catalysis and green chemistry in an economic context, showing how these potential new technologies may become useful to business. Fundamentals and specific examples are included to guide the transformation of idea to innovation and business. Offering an overview of the new possibilities for creating business in catalysis, energy and green chemistry, this book is a beneficial tool for students, researchers and academics in chemical and biochemical engineering. - Discusses new developments in catalysis, energy and green chemistry from the perspective of converting ideas to innovation and business - Presents case histories, preparation of business plans, patent protection and IP rights, creation of start-ups, research funds and successful written proposals - Offers an interdisciplinary approach combining science and business

Basic Science of PET Imaging

Basic Science of PET Imaging
Author: Magdy M. Khalil
Publisher: Springer
Total Pages: 621
Release: 2016-11-07
Genre: Medical
ISBN: 3319400703

This book offers a wide-ranging and up-to-date overview of the basic science underlying PET and its preclinical and clinical applications in modern medicine. In addition, it provides the reader with a sound understanding of the scientific principles and use of PET in routine practice and biomedical imaging research. The opening sections address the fundamental physics, radiation safety, CT scanning dosimetry, and dosimetry of PET radiotracers, chemistry and regulation of PET radiopharmaceuticals, with information on labeling strategies, tracer quality control, and regulation of radiopharmaceutical production in Europe and the United States. PET physics and instrumentation are then discussed, covering the basic principles of PET and PET scanning systems, hybrid PET/CT and PET/MR imaging, system calibration, acceptance testing, and quality control. Subsequent sections focus on image reconstruction, processing, and quantitation in PET and hybrid PET and on imaging artifacts and correction techniques, with particular attention to partial volume correction and motion artifacts. The book closes by examining clinical applications of PET and hybrid PET and their physiological and/or molecular basis in conjunction with technical foundations in the disciplines of oncology, cardiology and neurology, PET in pediatric malignancy and its role in radiotherapy treatment planning. Basic Science of PET Imaging will meet the needs of nuclear medicine practitioners, other radiology specialists, and trainees in these fields.