Pathogenic Escherichia Coli
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| Author | : Michael Donnenberg |
| Publisher | : Elsevier |
| Total Pages | : 453 |
| Release | : 2002-10-09 |
| Genre | : Science |
| ISBN | : 0080494811 |
Although most strains of E. coli bacteria are harmless and live in the intestines of healthy humans and animals, several strains can produce powerful toxins and cause severe illness in humans. This versatile pathogen is best known for being transmitted to humans through contaminated foods — such as undercooked meat and unpasteurized fruit juice — and has attracts much attention when serious outbreaks occur. E. coli is capable of causing a wide variety of diseases — from urinary tract infections to meningitis. A considerable amount of media coverage has recently been devoted to one particular strain of E. coli, responsible for an estimated 73,000 cases of infection and 61 deaths in the United States each year. Knowing more about the biology, the evolution, and the genetic basis of this pathogen is crucial to future prevention of infection and illness. Pathogenic E. coli is a unique, comprehensive analysis of the biology and molecular mechanisms that enable this ubiquitous organism to thrive. Leading investigators in the field discuss the molecular basis of E. coli pathogenesis followed by chapters on genomics and evolution. Detailed descriptions of distinct strains reveal the molecular pathogenesis of each and the causes of intestinal and extra-intestinal infections in humans. Pathogenic E. coli concludes with a presentation of virulance factors, common to two or more pathotypes. This unique collection presents timely and vital information on understanding the inner workings of E. coli, which will lend key insights into disease prevention research. - Single source of information of E. coli pathogenesis - Expert authors - Comprehensive coverage - Molecular mechanisms - Biology, evolution and genomics - Recent advances
| Author | : Stefano Morabito |
| Publisher | : Caister Academic Press Limited |
| Total Pages | : 0 |
| Release | : 2014 |
| Genre | : Science |
| ISBN | : 9781908230379 |
In recent years, a great deal of knowledge has accumulated on the features associated with the virulence of pathogenic E. coli. A large number of virulence genes have been identified and their products characterized. Great strides have been made in the understanding of the pathogenic mechanisms and the bacterium-host interaction. However, much remains elusive in the understanding of pathogenicity at a cellular and sub-cellular level. This is largely due to E. coli genome's plasticity: it generates great variability and facilitates the rapid emergence of new pathogenic variants. Elucidating the mechanisms underlying the evolution of these pathogens and their interactions with the host are key stages for disease prevention. This book reviews the most important recent findings of the studies on pathogenic E. coli, providing a timely overview of the field. The topics covered include: epidemiology of the disease in humans and animals and the biological mechanisms that shaped the pathogenic types of E. coli * shiga toxins * subtilase cytotoxin * cell cycle modulating toxins * the heat stable and heat labile enterotoxins * haemolysins * structural, molecular, and functional characteristics of A/E lesions * colonization factor antigens of ETEC * enteroaggregative adhesion * host cell invasion * the development of vaccinal strategies to confront the burden of disease. The chapters are written from a molecular and cellular biology standpoint, but also include discussions of the findings with a wider perspective, including considerations of public health and the impact on animal productions. The book will be essential reading for everyone working on these and related pathogens.
| Author | : |
| Publisher | : Academic Press |
| Total Pages | : 719 |
| Release | : 2013-11-08 |
| Genre | : Science |
| ISBN | : 0124159761 |
The second edition of Microbiology of Waterborne Diseases describes the diseases associated with water, their causative agents and the ways in which they gain access to water systems. The book is divided into sections covering bacteria, protozoa, and viruses. Other sections detail methods for detecting and identifying waterborne microorganisms, and the ways in which they are removed from water, including chlorine, ozone, and ultraviolet disinfection. The second edition of this handbook has been updated with information on biofilms and antimicrobial resistance. The impact of global warming and climate change phenomena on waterborne illnesses are also discussed. This book serves as an indispensable reference for public health microbiologists, water utility scientists, research water pollution microbiologists environmental health officers, consultants in communicable disease control and microbial water pollution students. Focuses on the microorganisms of most significance to public health, including E. coli, cryptosporidium, and enterovirus Highlights the basic microbiology, clinical features, survival in the environment, and gives a risk assessment for each pathogen Contains new material on antimicrobial resistance and biofilms Covers drinking water and both marine and freshwater recreational bathing waters
| Author | : Busi Siddhardha |
| Publisher | : Springer Nature |
| Total Pages | : 685 |
| Release | : 2020-03-28 |
| Genre | : Science |
| ISBN | : 9811516952 |
This book provides essential insights into microbial pathogenesis, host-pathogen interactions, and the anti-microbial drug resistance of various human pathogens on the basis of various model organisms. The initial sections of the book introduce readers to the mechanisms of microbial pathogenesis, host-pathogen interactions, anti-microbial drug resistance, and the dynamics of biofilm formation. Due to the emergence of various microbial resistant strains, it is especially important to understand the prognosis for microbial infections, disease progression profiles, and mechanisms of resistance to antibiotic therapy in order to develop novel therapeutic strategies. In turn, the second part of the book presents a comparative analysis of various animal models to help readers understand microbial pathogenesis, host-pathogen interactions, anti-microbial drug discovery, anti-biofilm therapeutics, and treatment regimes. Given its scope, the book represents a valuable asset for microbiologists, biotechnologists, medical professionals, drug development researchers, and pharmacologists alike.
| Author | : Michael Donnenberg |
| Publisher | : Academic Press |
| Total Pages | : 599 |
| Release | : 2013-06-12 |
| Genre | : Science |
| ISBN | : 0123977770 |
The 2e of Escherichia coli is a unique, comprehensive analysis of the biology and molecular mechanisms that enable this ubiquitous organism to thrive. Leading investigators in the field discuss the molecular basis of E. coli pathogenesis followed by chapters on genomics and evolution. Detailed descriptions of distinct strains reveal the molecular pathogenesis of each and the causes of intestinal and extra-intestinal infections in humans. This work concludes with a presentation of virulence factors common to two or more pathotypes. The book is a great resource for references and up-to-date knowledge for anyone who studies E. coli pathogenesis, either as established investigators or investigators new to the field. It is also an excellent text for those who teach mechanisms of pathogenesis to graduate students and medical students and wish to have a source of knowledge from which to develop lectures. - Offers a single source of information of E. coli pathogenesis written by expert authors - Presents comprehensive coverage on molecular mechanisms, biology, evolution and genomics and recent advances
| Author | : Arun K. Bhunia |
| Publisher | : Springer |
| Total Pages | : 377 |
| Release | : 2018-05-21 |
| Genre | : Technology & Engineering |
| ISBN | : 1493973495 |
This book primarily covers the general description of foodborne pathogens and their mechanisms of pathogenesis, control and prevention, and detection strategies, with easy-to-comprehend illustrations. The book is an essential resource for food microbiology graduate or undergraduate students, microbiology professionals, and academicians involved in food microbiology, food safety, and food defense-related research or teaching. This new edition covers the significant progress that has been made since 2008 in understanding the pathogenic mechanism of some common foodborne pathogens, and the host-pathogen interaction. Foodborne and food-associated zoonotic pathogens, responsible for high rates of mortality and morbidity, are discussed in detail. Chapters on foodborne viruses, parasites, molds and mycotoxins, and fish and shellfish are expanded. Additionally, chapters on opportunistic and emerging foodborne pathogens including Nipah virus, Ebola virus, Aeromonas hydrophila, Brucella abortus, Clostridium difficile, Cronobacter sakazakii, and Plesiomonas shigelloides have been added. The second edition contains more line drawings, color photographs, and hand-drawn illustrations.
| Author | : Luis Rodrigo |
| Publisher | : BoD – Books on Demand |
| Total Pages | : 236 |
| Release | : 2020-09-30 |
| Genre | : Medical |
| ISBN | : 1839625236 |
Gram-negative Escherichia coli (E. coli) bacteria are the most numerous commensal aerobic germs located in the human colon. Diarrhea caused by E. coli pathogenic strains is a major cause of death in developing countries, especially the sub-Saharan and South Asian areas. Some strains cause diarrhea, and all of them may produce an infectious disease. This book includes ten chapters covering the main aspects of infections related to E. coli, their pathogenic mechanisms, treatments, and resistance to diverse antibiotics.
| Author | : United States. Food and Drug Administration. Division of Microbiology |
| Publisher | : |
| Total Pages | : 180 |
| Release | : 1969 |
| Genre | : Microbiology |
| ISBN | : |
| Author | : Eduardo A. Groisman |
| Publisher | : Academic Press |
| Total Pages | : 863 |
| Release | : 2001-01-09 |
| Genre | : Medical |
| ISBN | : 0080539580 |
Principles of Bacterial Pathogenesis presents a molecular perspective on a select group of bacterial pathogens by having the leaders of the field present their perspective in a clear and authoritative manner. Each chapter contains a comprehensive review devoted to a single pathogen. Several chapters include work from authors outside the pathogenesis field, providing general perspectives on the evolution, regulation, and secretion of virulence and determinants. - Explains the basic principles of bacterial pathogenesis - Covers diverse aspects integrating regulation, cellular microbiology and evolution of microbial disease of humans - Discusses current strategies for the identification of virulence determinants and the methods used by microbes to deliver virulence factors - Presents authoritative treatises of the major disease microorganisms
| Author | : Lucia Rivas |
| Publisher | : Springer |
| Total Pages | : 114 |
| Release | : 2015-01-28 |
| Genre | : Technology & Engineering |
| ISBN | : 1493923463 |
This Brief will review the methods that are currently available for the detection, isolation, and typing of pathogenic E. coli with a particular focus on foodborne diseases caused by the Shiga toxigenic E. coli group, which have been implicated in a number of significant outbreaks in recent years. Pathogenic forms of E. coli can cause a variety of diarrheal diseases in hosts due to the presence of specific colonization and virulence factors, and pathogenicity-associated genes, which are generally not present in other E. coli. Six pathotypes of pathogenic E. coli are recognized (Shiga toxigenic E. coli, Enteropathogenic E. coli, Enterotoxigenic E. coli, Enteroinvasive E. coli, Enteroaggregative E. coli and Diffusely Adherent E. coli) and certain strains among these groups are major public health concerns due to the severity of disease that they can cause. Methods to detect and isolate these pathogens from a variety of sources are constantly evolving. In addition, the accumulation of knowledge on these pathogens allows for improved intervention strategies.
