Pathogenesis, Treatment and Prevention of Leishmaniasis

Pathogenesis, Treatment and Prevention of Leishmaniasis
Author: Mukesh Samant
Publisher: Academic Press
Total Pages: 281
Release: 2021-08-18
Genre: Medical
ISBN: 0128227982

Leishmaniasis is a neglected tropical disease that is known to be transmitted by 90 different species of sandflies which carry 20 Leishmania species that cause human infection particularly in endemic countries. Pathogenesis, Treatment, and Prevention of Leishmaniasis aims to provide information on this vector-borne disease and explore strategies for diagnosis and treatment. The book begins with an overview of leishmaniasis which includes historical and future perspectives of the disease. It also discusses the clinical manifestation of the disease, mechanisms of infection, therapeutic strategies, diagnostics, prevention, and cure of Leishmania parasite. The book goes on to explain new insights and challenges in the development of promising drug targets, biomarkers identification and advance vaccination strategies against leishmaniasis. Chapter contributions brings together diverse areas of expertise making Pathogenesis, Treatment, and Prevention of Leishmaniasis aims to bring together elements of leishmaniasis into one place and be a valuable resource for researchers, health care professionals, and graduate students, working in the field of leishmaniasis. - Provides an overview Leishmania and leishmanisis which include its history, transmission, clinical picture, and treatment - Discusses novel approaches to study parasite infection and treatment - Explores recent advances in the development of diagnostic kits, drug development and various vaccination strategies

Pathogenesis of Leishmaniasis

Pathogenesis of Leishmaniasis
Author: Abhay Satoskar
Publisher: Springer Science & Business
Total Pages: 98
Release: 2014-04-19
Genre: Medical
ISBN: 1461491088

This book discusses recent developments in several laboratories studying leishmaniasis. Sequencing of the human genome, as well as of the leishmania genome, has led to significant advances in our understanding of host-immune responses against leishmania, and mechanisms of infection-induced pathology, which is responsible for morbidity and mortality. Pathogenesis of Leishmaniasis focuses on the latest basic research into leishmaniasis, but also addresses how advances in understanding can be applied to prevention, control and treatment of what the WHO has classified a neglected tropical disease.

Drug Resistance in Leishmania Parasites

Drug Resistance in Leishmania Parasites
Author: Alicia Ponte-Sucre
Publisher: Springer Science & Business Media
Total Pages: 458
Release: 2012-09-04
Genre: Medical
ISBN: 3709111250

One of the main problems concerning therapeutic tools for the treatment of parasitic diseases, including leishmaniasis, is that some field parasites are naturally resistant to the classical drugs; additionally, current therapies may select parasites prone to be resistant to the applied drugs. These features are (at least partially) responsible for the disappointing persistence of the disease and resultant deaths worldwide. This book provides a comprehensive view of the pathology of the disease itself, and of parasitic drug resistance, its molecular basis, consequences and possible treatments. Scientists both from academic fields and from the industry involved in biomedical research and drug design, will find in this book a valuable and fundamental guide that conveys the knowledge needed to understand and to improve the success in combating this disease worldwide.

Imported Infectious Diseases

Imported Infectious Diseases
Author: Fernando Cobo
Publisher: Elsevier
Total Pages: 299
Release: 2014-10-07
Genre: Medical
ISBN: 1908818735

The increase of immigrant population in developed countries (mainly in Europe and North America) together with an important increase of international travel worldwide are the two most important causes that have contributed to the introduction and diagnosis of imported/tropical infectious diseases in these countries. These factors have had an important impact in developed countries in both social and economic aspects. Imported Infectious Diseases focuses not only on describing the infections, but also in evaluating the current epidemiology, the economic and social impact and the possibility to apply immunization measures and vaccines. The main purpose of this book is to give an overview of the current most important and frequent imported infectious diseases in developed countries. The first chapter informs about the medical services that are being offered to the immigrants in the main developed countries depending on the legal situation. Following chapters describe the main surveillance systems for these kinds of diseases, mainly in Europe and North America. Finally, remaining chapters contain sections on epidemiology, pathogenesis, clinical features, diagnosis, treatment and prevention.

Tropical Dermatology

Tropical Dermatology
Author: Roberto Arenas
Publisher: CRC Press
Total Pages: 378
Release: 2001-01-01
Genre: Science
ISBN: 1498712754

Tropical diseases are not merely a group of nosologic diseases indigenous to the intertropical zone. Many are diseases of poor public health originating from poverty, ignorance, and population upheaval. Tropical dermatoses represent a public health problem in 127 countries with a population of 3 billion people who do not have access to health care.

Neglected Tropical Diseases - Sub-Saharan Africa

Neglected Tropical Diseases - Sub-Saharan Africa
Author: John Gyapong
Publisher: Springer
Total Pages: 421
Release: 2016-01-13
Genre: Medical
ISBN: 3319254715

This book provides an overview on the major neglected tropical diseases (NTDs) occurring in Sub-Saharan Africa, such as Leishmaniasis, Buruli Ulcer and Schistosomiasis. In well-structured chapters epidemiology and biology of these parasitic diseases will be discussed in detail. Further, diagnostics and therapeutic approaches as well as prevention strategies will be reviewed. The book will be of interest to basic researchers and clinicians engaged in infectious disease, tropical medicine, and parasitology, and a must-have for scientists specialized in the characteristics of the Sub-Saharan region.

Leishmania and Leishmaniasis

Leishmania and Leishmaniasis
Author: Awanish Kumar
Publisher: Springer Science & Business Media
Total Pages: 90
Release: 2013-09-13
Genre: Medical
ISBN: 1461488699

​Leishmania-related illnesses remain among the world’s deadliest neglected tropical diseases, affecting approximately 12 million people in 88 countries. The mortality rate is substantial, contributing to nearly two million disability-adjusted life years. As more is understood about this parasite and its effects, work toward prevention, control, and treatment continues apace. Leishmania and Leishmaniasis will address the parasite and its attendant disease, which manifests in three syndromes: Visceral (VL), Cutaneous (CL) and Mucocutaneous Leishmaniasis (ML). The morphology and life cycles of the various species will be among the topics addressed in Part One. Part Two will focus on immunology, including host-immune response to Leishmania infection, cross-immunity between the different species and adoptive transfer of immunity. Parts Three and Four will address how Leishmania invade and survive, the clinical features of the disease, and its diagnosis. Drugs, vaccines and treatment will be thoroughly explored, including experimental models of therapeutics. Leishmania and Leishmaniasis will provide a thorough examination of a parasite, the illnesses it causes and the misery it continues to visit upon large segments of the population.​

Parasitology and Microbiology Research

Parasitology and Microbiology Research
Author: Gilberto Antonio Bastidas Pacheco
Publisher: BoD – Books on Demand
Total Pages: 376
Release: 2020-06-17
Genre: Medical
ISBN: 1789859018

The study of both unicellular and multicellular living beings and the diseases they produce from a biological point of view requires constant review of their relationship with their host and environment, given their indisputable sanitary importance. In this sense, in parasitology and microbiology, updated and concise information on life cycle, taxonomic classification, clinical manifestations, diagnosis, treatment, epidemiological behavior, and control measures is of vital importance. This is what we pursue with this book. The approach to parasitology and microbiology and the research that is carried out on it is unquestionable because the associations between life forms have been present from the very beginning of life.Research in parasitology and microbiology is necessary and indispensable for controlling diseases that affect much of the world with serious economic and social consequences. The challenge is to promote research to keep these diseases at bay. This book shows what has been done up to now and what can be done in the future to combat infectious diseases.

Immigrant Medicine E-Book

Immigrant Medicine E-Book
Author: Patricia Frye Walker
Publisher: Elsevier Health Sciences
Total Pages: 783
Release: 2007-10-25
Genre: Medical
ISBN: 0323070574

Immigrant Medicine is the first comprehensive guide to caring for immigrant and refugee patient populations. Edited by two of the best-known contributors to the growing canon of information about immigrant medicine, and written by a geographically diverse collection of experts, this book synthesizes the most practical and clinically relevant information and presents it in an easy-to-access format. An invaluable resource for front-line clinicians and other healthcare professionals, public health officials, and policy makers, Immigrant Medicine is destined to become the benchmark reference in this emerging field. Features expert guidance on data collection, legal, interpretive and social adjustment issues, as well as best practices in caring for immigrants to help you confidently manage all aspects of immigrant medicine. Includes detailed discussions on major depression, post traumatic stress disorder, and issues related to torture so you can effectively diagnose and treat common psychiatric issues. Covers international and new-arrival screening and immunizations offering you invaluable advice. Presents a templated diseases/disorders section with discussions on tuberculosis, hepatitis B, and common parasites that helps you easily manage the diseases and syndromes you are likely to encounter. Provides boxed features and tables, differential diagnoses, and treatment algorithms to help you absorb information at a glance.