Pathogenesis of Wound and Biomaterial-Associated Infections

Pathogenesis of Wound and Biomaterial-Associated Infections
Author: Torkel Wadström
Publisher: Springer Science & Business Media
Total Pages: 537
Release: 2012-12-06
Genre: Technology & Engineering
ISBN: 1447134540

Despite the recent advances in medical treatment, patients suffering from wounds such as burns or receiving surgical implants are still in great danger of infection. This has called attention to the need for better understanding of infections at the molecular level. Scientists from various disciplines summarize our knowledge today and investigate how methods to avoid wound and biomaterial-associated infections can be developed. These methods include new antibiotics, surgical strategies to prevent infection, and ways to stimulate the immune system and the tissue healing process. Specific topics include: the definition of microbial cell surface determinants important for adhesion to graft; the definition of extracellular bacterial enzymes and toxins involved in tissue breakdown and the local spread of infection; the prevention of the systemic spreading of infection with immunoglobulins and antibiotics; and the problem of multiple antibiotic resistance in most versatile pathogens.

Biofilm Infections

Biofilm Infections
Author: Thomas Bjarnsholt
Publisher: Springer
Total Pages: 0
Release: 2014-10-11
Genre: Science
ISBN: 9781489982285

This book will cover both the evidence for biofilms in many chronic bacterial infections as well as the problems facing these infections such as diagnostics and treatment regimes. A still increasing interest and emphasis on the sessile bacterial lifestyle biofilms has been seen since it was realized that that less than 0.1% of the total microbial biomass lives in the planktonic mode of growth. The term was coined in 1978 by Costerton et al. who defined the term biofilm for the first time.In 1993 the American Society for Microbiology (ASM) recognised that the biofilmmode of growth was relevant to microbiology. Lately many articles have been published on the clinical implications of bacterial biofilms. Both original articles and reviews concerning the biofilm problem are available.

Therapeutic Dressings and Wound Healing Applications

Therapeutic Dressings and Wound Healing Applications
Author: Joshua Boateng
Publisher: John Wiley & Sons
Total Pages: 444
Release: 2020-03-09
Genre: Science
ISBN: 1119433266

The latest research on techniques for effective healing of chronic and difficult to heal wounds The healing of chronic wounds is a global medical concern, specifically for patients suffering from obesity and type II diabetes. Therapeutic Dressing and Wound Healing Applications is an essential text for research labs, industry professionals, and general clinical practitioners that want to make the shift towards advanced therapeutic dressing and groundbreaking wound application for better healing. This book takes a clinical and scientific approach to wound healing, and includes recent case studies to highlight key points and areas of improvement. It is divided into two key sections that include insight into the biochemical basis of wounds, as well as techniques and recent advancements. Chapters include information on: ● Debridement and disinfection properties of wound dressing ● Biofilms, silver nanoparticles, and honey dressings ● Clinical perspectives for treating diabetic wounds ● Treating mixed infections ● Wound healing and tissue regeneration treatments ● Gene based therapy, 3D bioprinting and freeze-dried wafers Anyone looking to update and improve the treatment of chronic wounds for patients will find the latest pertinent information in Therapeutic Dressing and Wound Healing Applications.

Wound Healing and Skin Physiology

Wound Healing and Skin Physiology
Author: Peter Altmeyer
Publisher: Springer Science & Business Media
Total Pages: 701
Release: 2012-12-06
Genre: Medical
ISBN: 3642778828

On the occasion of the European Congress on Wound Healing and Skin Physiology (Bochum, Germany, November 1992), an international team of scientists and clinicians discussed the core topics in this important field of dermatological and surgical research. Themes include morphology and physiology, microcirculation and angiogenesis, biochemistry and immunology, microbiology and wound infection, non-invasive measurement techniques, wound repair, surgical treatment, dressings, and agents that promote wound healing.

Bioengineering In Wound Healing: A Systems Approach

Bioengineering In Wound Healing: A Systems Approach
Author: Martin L Yarmush
Publisher: World Scientific
Total Pages: 394
Release: 2017-03-24
Genre: Technology & Engineering
ISBN: 9813144599

What is a wound, how does it heal, and how can we prevent scarring? The concept of wound healing has puzzled humans even before the advent of modern medicine.In recent years, bioengineering has tackled the problems of cancer, tissue engineering and molecular manufacturing. The broad spectrum of technologies developed in these fields could potentially transform the wound care practice. However, entering the world of wound healing research is challenging — a broad spectrum of knowledge is required to understand wounds and improve healing.This book provides an essential introduction of the field of wound healing to bioengineers and scientists outside the field of medicine. Written by leading researchers from various fields, this book is a comprehensive primer that gives readers a holistic understanding of the field of wound biology, diagnostics and treatment technologies.

Materials for Medical Application

Materials for Medical Application
Author: Robert B. Heimann
Publisher: Walter de Gruyter GmbH & Co KG
Total Pages: 805
Release: 2020-08-24
Genre: Science
ISBN: 3110619318

This book gives an introduction to the highly interdisciplinary field of biomaterials. It concisely summarizes properties, synthesis and modification of materials such as metals, ceramics, polymers or composites. Characterization, in vitro and in vivo testing as well as a selection of various applications are also part of this inevitable guide.

Management of Periprosthetic Joint Infections (PJIs)

Management of Periprosthetic Joint Infections (PJIs)
Author: J.J. Chris Arts
Publisher: Woodhead Publishing
Total Pages: 306
Release: 2016-10-25
Genre: Science
ISBN: 0081002424

Management of Periprosthetic Joint Infections (PJIs): Management of PJIs discusses periprosthetic joint infection (PJI), a fairly rare occurrence that is nonetheless one of the most serious complications in joint replacement surgery. Intricate interactions between the pathogen, the host, and the implant can result in PJIs which are not only physically devastating for the patient, but also financially crippling for health authorities and insurance companies. Actions taken to minimize the risk of PJIs can be extremely challenging for the orthopaedic community. Consequently, new research, which is detailed in this comprehensive book, is being undertaken to minimize and manage these challenging infections. - Provides essential background knowledge on the mechanisms and identification of PJIs - Dedicated chapters focus on the complex, but vital eccentricities between PJIs in different areas of the body - Contains contributions from a mixture of clinical and academic experts in the field, thus ensuring balanced coverage

Antibiofilm Agents

Antibiofilm Agents
Author: Kendra P. Rumbaugh
Publisher: Springer Science & Business Media
Total Pages: 495
Release: 2014-05-08
Genre: Science
ISBN: 3642538339

This book provides a survey of recent advances in the development of antibiofilm agents for clinical and environmental applications. The fact that microbes exist in structured communities called biofilms has slowly become accepted within the medical community. We now know that over 80% of all infectious diseases are biofilm-related; however, significant challenges still lie in our ability to diagnose and treat these extremely recalcitrant infections. Written by experts from around the globe, this book offers a valuable resource for medical professionals seeking to treat biofilm-related disease, academic and industry researchers interested in drug discovery and instructors who teach courses on microbial pathogenesis and medical microbiology.

Titanium in Medical and Dental Applications

Titanium in Medical and Dental Applications
Author: Francis Froes
Publisher: Woodhead Publishing
Total Pages: 656
Release: 2018-05-09
Genre: Technology & Engineering
ISBN: 0128124571

Titanium in Medical and Dental Applications is an essential reference book for those involved in biomedical materials and advanced metals. Written by well-known experts in the field, it covers a broad array of titanium uses, including implants, instruments, devices, the manufacturing processes used to create them, their properties, corrosion resistance and various fabrication approaches. Biomedical titanium materials are a critically important part of biomaterials, especially in cases where non-metallic biomedical materials are not suited to applications, such as the case of load-bearing implants. The book also covers the use of titanium for implants in the medical and dental fields and reviews the use of titanium for medical instruments and devices. - Provides an understanding of the essential and broad applications of Titanium in both the medical and dental industries - Discusses the pathways to manufacturing titanium into critical biomedical and dental devices - Includes insights into further applications within the industry

Surface Coating and Modification of Metallic Biomaterials

Surface Coating and Modification of Metallic Biomaterials
Author: Cuie Wen
Publisher: Woodhead Publishing
Total Pages: 449
Release: 2015-03-31
Genre: Technology & Engineering
ISBN: 1782423168

Despite advances in alternative materials, metals are still the biomaterial of choice for a number of clinical applications such as dental, orthopedic and cardiac implants. However, there are a number of intrinsic problems associated with implanting metal in the biological environment, such as wear, corrosion, biocompatibility and toxicity, which must be addressed. Modern technology has enabled scientists to modify metal surfaces or apply special coatings to metals to improve their performance safety. Surface Coating and Modification of Metallic Biomaterials will discuss the most important modification techniques and coatings for metals, first covering the fundamentals of metals as a biomaterial and then exploring surface modification techniques and coatings. - An expansive overview of surface modification techniques for biomedical use - In-depth exploration of issues arising from metal biomaterial use - Includes examples of applications in a clinical setting