Pathogenesis and Modelling of Infection Dynamics in Ralstonia Solanacearum

Pathogenesis and Modelling of Infection Dynamics in Ralstonia Solanacearum
Author: Gaofei Jiang
Publisher:
Total Pages: 237
Release: 2016
Genre:
ISBN:

Bacterial wilt caused by Ralstonia solanacearum limits the global production of many crops. The extensive genetic diversity of the bacterium has in recent years led to the concept of a R. solanacearum Species Complex (RSSC). Genome sequencing of over 30 representative strains of the each phylogenetic groups has broadened our knowledge of the evolution and speciation of RSSC. This enabled the identification of novel virulence-associated functions. Furthermore, a large number of studies have been carried on plants-R. solanacearum interactions and shed light on the genetics, molecular biology, and disease development. These studies have documented the infection strategies of R. solanacearum employed to cope with plant immune defenses. Although these qualitative investigations are a basis to understand the pathogenesis of R. solanacearum, they are insufficient to know whether or not plants will be diseased. These fundamental questions require a quantitative understanding of the processes responsible for the rise, dissemination and fall of the infection populations of R. solanacearum. This work pioneered the quantitative study in plant bacterial pathogens by addressing the following question: "How many R. solanacearum individuals enter from the root to establish the bacterial wilt disease in plant?" It allowed us to determine what factors control the infection dynamics of R. solanacearum within the host plant. This scientific question requires a re-examination on the life cycle of R. solanacearum and the precise characterization of the whole infection process in plant. Seven dynamical parameters were refined from five subsequent infection steps of R. solanacearum in host plant. Then, we established a mathematical model of within-host dynamics of the bacterium by the integration of these parameters. The model suggests that the whole population dynamics influences the founding population/bottleneck size of R. solanacearum. The in vivo assessment of parameters and their interactions predicted a small founding population size, around four hundred bacterial cells, which was confirmed by experimental measurements with a probabilistic approach. To understand mechanisms restricting R. solanacearum population, we further investigated impacts of bacterial virulence, plant barriers and environmental factor on the infection founding population. We showed that infection bottleneck is mainly modulated by the pathogen (virulence arsenal), the host (physical and immunity traits) and the environmental conditions (temperature).

Bacterial Wilt Disease and the Ralstonia Solanacearum Species Complex

Bacterial Wilt Disease and the Ralstonia Solanacearum Species Complex
Author: Caitilyn Allen
Publisher:
Total Pages: 540
Release: 2005
Genre: Medical
ISBN:

The bacterial wilt diseases caused by members of the Ralstonia solanacearum species complex have never been more important. The research presented in this volume reveals a pathogen on the move, with a growing global profile. While these diseases inflict ongoing and increasing crop losses on subsistence farmers, the pathogen now has significant political and economic impact in the developed world.This book, based on the 3rd International Bacterial Wilt Symposium, covers topics ranging from the basic biology of the host-pathogen interaction to applied research, designed to immediately address disease losses in the field. Contributors to the book span a broad range of applied and basic biologists. They work in all parts of the world, offering current data on sustainable low-tech disease control practices and on R. solanacearum as a model system for understanding molecular plant-microbe interactions.Bacterial Wilt Disease and the Ralstonia solanacearum Species Complex opens with two key reviews. One presents a thoughtful analysis of international collaborations on bacterial wilt research in the context of a review of literature published on the topic. The second is a global assessment of the current impact of bacterial wilt. Although there are still significant gaps in the data available, for the first time a general idea of the real impact and extent of these diseases around the world is presented.Topics covered in this resource include: epidemiology, disease management, breeding and deployment, host plant response and disease management, pathogen genetics, R. solanacearum in banana and plantains, and diversity and detection. Experts provide overviews focusing on the pressing research needs in each area. These overview chapters are intended to give the reader the best current understanding of the topic and to suggest promising directions for future research.Global Impact of R. solanacearum:R. solanacearum is a contentious topic in agricultural trade negotiations in the European Union and is subject to strict quarantine and eradication regulations in the United States. This legislation has had unforeseen economic impacts on laborers in developing nations where millions of ornamental plant cuttings are produced for the North American and European markets. In addition, reports at the 3rd International Bacterial Wilt Symposium indicated that the most rapid and alarming increases in bacterial wilt disease incidence around the world are on potatoes, bananas and plantains. More than ever, scientists who work with this pathogen must recognize that although bacterial wilt certainly can cause severe crop losses on a local scale, it also plays a complex and significant role in the worldwide agricultural matrix.

Bacterial Wilt Disease

Bacterial Wilt Disease
Author: Philippe Prior
Publisher: Springer Science & Business Media
Total Pages: 451
Release: 2013-06-29
Genre: Science
ISBN: 3662035928

Jointly published with INRA, Paris. Bacterial wilt, caused by Ralstonia solanacearum, is a very destructive plant disease that attacks over 450 different species, including many of the most important economic crop plants. Often endemic, the bacterium transmits through the soil, penetrates the plant root system and eventually causes irreversible wilting and death. This book summarizes the current information on bacterial wilt for both the basic research community and for concerned professionals who are faced with the disease in the field, offering the latest approaches to diagnosis and control of the disease. Emphasis is placed on integrated and biologically sustainable control methods. Also presented is the most recent genetic/biochemical research exploring the interaction between the bacterium and its plant host at the molecular level.

Model Organisms for Microbial Pathogenesis, Biofilm Formation and Antimicrobial Drug Discovery

Model Organisms for Microbial Pathogenesis, Biofilm Formation and Antimicrobial Drug Discovery
Author: Busi Siddhardha
Publisher: Springer Nature
Total Pages: 685
Release: 2020-03-28
Genre: Science
ISBN: 9811516952

This book provides essential insights into microbial pathogenesis, host-pathogen interactions, and the anti-microbial drug resistance of various human pathogens on the basis of various model organisms. The initial sections of the book introduce readers to the mechanisms of microbial pathogenesis, host-pathogen interactions, anti-microbial drug resistance, and the dynamics of biofilm formation. Due to the emergence of various microbial resistant strains, it is especially important to understand the prognosis for microbial infections, disease progression profiles, and mechanisms of resistance to antibiotic therapy in order to develop novel therapeutic strategies. In turn, the second part of the book presents a comparative analysis of various animal models to help readers understand microbial pathogenesis, host-pathogen interactions, anti-microbial drug discovery, anti-biofilm therapeutics, and treatment regimes. Given its scope, the book represents a valuable asset for microbiologists, biotechnologists, medical professionals, drug development researchers, and pharmacologists alike.

The Model Legume Medicago truncatula, 2 Volume Set

The Model Legume Medicago truncatula, 2 Volume Set
Author: Frans J. de Bruijn
Publisher: John Wiley & Sons
Total Pages: 1264
Release: 2020-01-29
Genre: Science
ISBN: 1119409160

Fully covers the biology, biochemistry, genetics, and genomics of Medicago truncatula Model plant species are valuable not only because they lead to discoveries in basic biology, but also because they provide resources that facilitate translational biology to improve crops of economic importance. Plant scientists are drawn to models because of their ease of manipulation, simple genome organization, rapid life cycles, and the availability of multiple genetic and genomic tools. This reference provides comprehensive coverage of the Model Legume Medicago truncatula. It features review chapters as well as research chapters describing experiments carried out by the authors with clear materials and methods. Most of the chapters utilize advanced molecular techniques and biochemical analyses to approach a variety of aspects of the Model. The Model Legume Medicago truncatula starts with an examination of M. truncatula plant development; biosynthesis of natural products; stress and M. truncatula; and the M. truncatula-Sinorhizobium meliloti symbiosis. Symbiosis of Medicago truncatula with arbuscular mycorrhiza comes next, followed by chapters on the common symbiotic signaling pathway (CSSP or SYM) and infection events in the Rhizobium-legume symbiosis. Other sections look at hormones and the rhizobial and mycorrhizal symbioses; autoregulation of nodule numbers (AON) in M. truncatula; Medicago truncatula databases and computer programs; and more. Contains reviews, original research chapters, and methods Covers most aspects of the M. truncatula Model System, including basic biology, biochemistry, genetics, and genomics of this system Offers molecular techniques and advanced biochemical analyses for approaching a variety of aspects of the Model Legume Medicago truncatula Includes introductions by the editor to each section, presenting the summary of selected chapters in the section Features an extensive index, to facilitate the search for key terms The Model Legume Medicago truncatula is an excellent book for researchers and upper level graduate students in microbial ecology, environmental microbiology, plant genetics and biochemistry. It will also benefit legume biologists, plant molecular biologists, agrobiologists, plant breeders, bioinformaticians, and evolutionary biologists.

Handbook of Soil Analysis

Handbook of Soil Analysis
Author: Marc Pansu
Publisher: Springer Science & Business Media
Total Pages: 996
Release: 2007-04-18
Genre: Science
ISBN: 3540312110

This handbook is a reference guide for selecting and carrying out numerous methods of soil analysis. It is written in accordance with analytical standards and quality control approaches. It covers a large body of technical information including protocols, tables, formulae, spectrum models, chromatograms and additional analytical diagrams. The approaches are diverse, from the simplest tests to the most sophisticated determination methods.

Phytobacteriology

Phytobacteriology
Author: J. D. Janse
Publisher: CABI
Total Pages: 368
Release: 2006
Genre: Medical
ISBN: 1845930355

This comprehensive manual of phytobacteriology is heavily illustrated with over 200 colour photographs and line illustrations. It begins by outlining the history and science of bacteriology and gives an overview of the diversity and versatility of complex bacteria. It then explains the characterization, identification and naming of complex bacteria, and explores how bacteria can cause disease and how plants react to such disease. The book also discusses the economic importance of bacterial diseases as well as strategies for their control and the reduction of crop losses. It concludes with fifty examples of plant pathogenic bacteria and the diseases that they cause.

Plant Virus Epidemiology

Plant Virus Epidemiology
Author:
Publisher: Elsevier
Total Pages: 556
Release: 2006-12-15
Genre: Science
ISBN: 0080466370

Published since 1953, Advances in Virus Research covers a diverse range of in-depth reviews providing a valuable overview of the current field of virology. In 2004, the Institute for Scientific Information released figures showing that the series has an Impact Factor of 2.576, with a half-life of 7.1 years, placing it 11th in the highly competitive category of Virology. * Edited by an experienced plant pathologist who has over 50 years experience in plant virus epidemiology* Covers topics such as Evolutionary epidemiology of plant virus disease, The control of tropical plant virus diseases, and Control of plant virus diseases* A valuable resource for students and researchers alike

Forest Pathology and Plant Health

Forest Pathology and Plant Health
Author: Matteo Garbelotto
Publisher: MDPI
Total Pages: 243
Release: 2018-04-13
Genre: Science
ISBN: 3038426717

This book is a printed edition of the Special Issue "Forest Pathology and Plant Health" that was published in Forests

Applied Plant Biotechnology for Improving Resistance to Biotic Stress

Applied Plant Biotechnology for Improving Resistance to Biotic Stress
Author: Palmiro Poltronieri
Publisher: Academic Press
Total Pages: 0
Release: 2019-09-18
Genre: Science
ISBN: 9780128160305

Applied Plant Biotechnology for Improvement of Resistance to Biotic Stress applies biotechnology insights that seek to improve plant genomes, thus helping them achieve higher resistance and optimal hormone signaling to increase crop yield. The book provides an analysis of the current state-of-the-art in plant biotechnology as applied to improving resistance to biotic stress. In recent years, significant progress has been made towards understanding the interplay between plants and their hosts, particularly the role of plant immunity in regulating, attenuating or neutralizing invading pathogens. As a result, there is a great need to integrate these insights with methods from biotechnology.