Particle Lung Interactions
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Author | : Peter Gehr |
Publisher | : CRC Press |
Total Pages | : 718 |
Release | : 2000-02-18 |
Genre | : Medical |
ISBN | : 0824746899 |
This wide-ranging, comprehensive reference presents the latest developments in aerosol science and interactions between particles and the respiratory tract-utilizing an inter-disciplinary approach that integrates advances in physics, chemistry, and engineering with the epidemiological and biomedical sciences, and focusing on the dynamics of particl
Author | : Peter Gehr |
Publisher | : CRC Press |
Total Pages | : 0 |
Release | : 2009-09-25 |
Genre | : Medical |
ISBN | : 9781420072563 |
Written by an expanded team of leading international scientists, the second edition thoroughly investigates research and therapies for managing adverse physiological effects of air-borne particles on the respiratory tract. The book examines the lung as the gateway for particle damage to organs outside the respiratory system and provide the information needed to understand and combat the numerous and varied ailments caused by inhaled particles.
Author | : Peter Gehr |
Publisher | : CRC Press |
Total Pages | : 324 |
Release | : 2009-09-25 |
Genre | : Medical |
ISBN | : 1420072579 |
Written by an expanded team of leading international scientists, the second edition thoroughly investigates research and therapies for managing adverse physiological effects of air-borne particles on the respiratory tract. The book examines the lung as the gateway for particle damage to organs outside the respiratory system and provide the informat
Author | : Günter Oberdörster |
Publisher | : |
Total Pages | : 207 |
Release | : 1990 |
Genre | : |
ISBN | : |
Author | : |
Publisher | : |
Total Pages | : 44 |
Release | : 1956 |
Genre | : |
ISBN | : |
Author | : Xian Ming Zeng |
Publisher | : CRC Press |
Total Pages | : 264 |
Release | : 2000-10-26 |
Genre | : Medical |
ISBN | : 113572976X |
Interactions between drug particulates are crucial in determining drug dispersion and deaggregation, and ultimately delivery efficiency. This book combines principles established in surface and colloidal chemistry with pharmaceutical powder technology. It discusses some of the factors affecting particulate interactions, and particle-fluid interaction in the respiratory tract. It review some of the studies carried out in dry powder formulation development, and proposes possible strategies in improving DPI efficiency. The majority of these principles are applicable to other pharmaceutical solid dosage forms (e.g. tablets and capsules).
Author | : United States. Public Health Service. Office of the Surgeon General |
Publisher | : |
Total Pages | : 728 |
Release | : 2010 |
Genre | : Government publications |
ISBN | : |
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Author | : Akira Tsuda |
Publisher | : CRC Press |
Total Pages | : 403 |
Release | : 2014-12-19 |
Genre | : Medical |
ISBN | : 1439892806 |
Nanoparticles have a physical dimension comparable to the size of molecular structures on the cell surface. Therefore, nanoparticles, compared to larger (e.g., micrometer) particles, are considered to behave differently when they interact with cells. Nanoparticles in the Lung: Environmental Exposure and Drug Delivery provides a better understanding
Author | : Ali Nokhodchi |
Publisher | : John Wiley & Sons |
Total Pages | : 392 |
Release | : 2015-08-03 |
Genre | : Science |
ISBN | : 1118799542 |
Drug therapy via inhalation route is at the cutting edge of modern drug delivery research. There has been significant progress on the understanding of drug therapy via inhalation products. However, there are still problems associated with their formulation design, including the interaction between the active pharmaceutical ingredient(s) (APIs), excipients and devices. This book seeks to cover some of the most pertinent issues and challenges of such formulation design associated with industrial production and desirable clinical outcome. The chapter topics have been selected with a view to integrating the factors that require consideration in the selection and design of device and formulation components which impact upon patient usability and clinical effectiveness. The challenges involved with the delivery of macromolecules by inhalation to both adult and pediatric patients are also covered. Written by leading international experts from both academia and industry, the book will help readers (formulation design scientists, researchers and post-graduate and specialized undergraduate students) develop a deep understanding of key aspects of inhalation formulations as well as detail ongoing challenges and advances associated with their development.
Author | : National Research Council (U.S.). Subcommittee on Airborne Particles |
Publisher | : |
Total Pages | : 376 |
Release | : 1979 |
Genre | : Science |
ISBN | : |