Part I Total Synthesis Of Ratjadone Part Ii Studies Toward The Total Synthesis Of Zoanthenol
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Directory of Graduate Research
| Author | : American Chemical Society. Committee on Professional Training |
| Publisher | : |
| Total Pages | : 1932 |
| Release | : 2005 |
| Genre | : Biochemistry |
| ISBN | : |
Faculties, publications and doctoral theses in departments or divisions of chemistry, chemical engineering, biochemistry and pharmaceutical and/or medicinal chemistry at universities in the United States and Canada.
Total Synthesis of (±)-Maoecrystal V
| Author | : Jianxian Gong |
| Publisher | : Springer |
| Total Pages | : 146 |
| Release | : 2014-07-08 |
| Genre | : Science |
| ISBN | : 3642543049 |
In this thesis, the author describes the total synthesis of natural product Maoecrystal V in detail. In the first part of the thesis, the author introduces the research background and reviews the research progress in total synthesis of Maoecrystal V. In the second part, the author develops a novel and concise approach for the stereo selective construction of the tetracyclic model system of Maoecrystal V. The model system is accomplished in 8 steps with 20% yield. In the third part, the author describes the first successful total synthesis of Maoecrystal V and investigates four strategies for constructing the key tetrahydrofuran oxa-bridge skeleton. The total synthesis starts from a known compound and is accomplished in 17 steps with 1.2% yield. The successful total synthesis of Maoecrystal V will contribute to the development of efficient synthetic strategies for natural products and other compounds with complex structures.
The Total Synthesis of Natural Products, Volume 6
| Author | : John ApSimon |
| Publisher | : John Wiley & Sons |
| Total Pages | : 306 |
| Release | : 2009-09-22 |
| Genre | : Science |
| ISBN | : 0470129573 |
The sixth volume of The Total Synthesis of Natural Products continues editor John ApSimon's exploration of one of the most promising areas for the future development of organic chemistry: synthesis. ApSimon has compiled the first definitive reference source of successful synthetic approaches to a wide variety of natural products. This new volume considers the total synthesis of triterpenes, carbohydrates, aromatic steroids, pyrrole pigments and genes first reported during the period from 1972 through 1982 in this series. The Total Synthesis of Natural Products, Volume Six forms an integral part of the invaluable working reference begun in Volumes One through Five, to which chemists may turn for the available data on the total synthesis of complex molecules. Lessons learned from the synthetic challenges presented here by various natural products will serve as a sound base for this continually evolving field.
The Total Synthesis of Natural Products, Volume 6
| Author | : John ApSimon |
| Publisher | : Wiley-Interscience |
| Total Pages | : 312 |
| Release | : 1984-07-02 |
| Genre | : Science |
| ISBN | : 9780471099000 |
The sixth volume of The Total Synthesis of Natural Products continues editor John ApSimon's exploration of one of the most promising areas for the future development of organic chemistry: synthesis. ApSimon has compiled the first definitive reference source of successful synthetic approaches to a wide variety of natural products. This new volume considers the total synthesis of triterpenes, carbohydrates, aromatic steroids, pyrrole pigments and genes first reported during the period from 1972 through 1982 in this series. The Total Synthesis of Natural Products, Volume Six forms an integral part of the invaluable working reference begun in Volumes One through Five, to which chemists may turn for the available data on the total synthesis of complex molecules. Lessons learned from the synthetic challenges presented here by various natural products will serve as a sound base for this continually evolving field.
Total Synthesis of Natural Products with Antimicrobial Activity
| Author | : Andrew Giltrap |
| Publisher | : Springer |
| Total Pages | : 285 |
| Release | : 2018-05-02 |
| Genre | : Science |
| ISBN | : 9811088063 |
This thesis focuses on the development of efficient and scalable total syntheses of natural products that can be used as preferred scaffolds for anti-infective drug discovery. It describes the total synthesis of two classes of antimicrobial non-ribosomal peptides (NRPs) – teixobactin and the skyllamycins – with subsequent biological evaluation. The first part describes the first total synthesis of teixobactin by means of a solid-phase peptide synthesis-macrolactamisation approach, yielding a synthetic natural product that can combat a number of clinically relevant Gram-positive bacterial pathogens. The second part describes the first total synthesis of skyllamycins A-C, a family of structurally complex cyclic NRPs, which inhibit the growth of the Pseudomonas aeruginosa biofilms that are responsible for significant mortality among cystic fibrosis patients.
Modern Natural Product Synthesis
| Author | : Masahisa Nakada |
| Publisher | : Springer |
| Total Pages | : 0 |
| Release | : 2024-06-02 |
| Genre | : Science |
| ISBN | : 9789819716180 |
In this book, key experts in the field of total synthesis of natural products in Japan describe the details of their synthesis routes including unexpected reactions and syntheses. By presenting detailed stories behind the total synthesis developments, including those routes that were unsuccessful the book provides the reader with a better understanding of how other researchers devise their strategy and overcome difficulties in their studies. The contributions in the book have focused on highlighting the research from Japan however it is appealing to researchers and students worldwide. This compilation of cutting-edge natural product synthesis provides high-quality expertise, especially to graduate students and young researchers, regarding research on synthetic organic chemistry. It can be utilized as teaching material in university seminars as well as provide guidance to researchers in the area of total synthesis. This is an open access book.
Synthetic Studies Toward the Total Synthesis of Fostriecin and Some Analogs
| Author | : Glenn Walton Phillips |
| Publisher | : |
| Total Pages | : 560 |
| Release | : 2006 |
| Genre | : Antineoplastic agents |
| ISBN | : |
