Functional Organization of Descending Supraspinal Fibre Systems to the Spinal Cord

Functional Organization of Descending Supraspinal Fibre Systems to the Spinal Cord
Author: R. Nyberg-Hansen
Publisher: Springer
Total Pages: 48
Release: 2013-11-11
Genre: Medical
ISBN: 366230435X

Recent advances in the neurophysiology of the spinal cord, due largely to the use of microelectrodes, have increased the demand for a detailed knowledge of its minute anatomy, including the exact sites and mode of termination of the various contingents of afferent fibres to the spinal grey matter, among them the descending supraspinal fibre systems. Anatomical data of this kind are indispensable for functional interpretations and for the analysis of the structural and functional organization of the spinal cord. The observation of REXED (1952, 1954) that the grey matter of the feline spinal cord may be subdivided on a cytoarchitectonic basis into ten different laminae, presumably representing, at least in part, functionally different regions, should serve as a stimulus to attempt more precise analysis of the intrinsic organi zation of the spinal cord. Furthermore REXED'S laminae provide a common basis of reference of the sites of termination of afferent fibre systems to the spinal grey matter and the localization of single units recorded from in neurophysiological experiments, and thus promise useful correlations between anatomical and physiological observations and their functional interpretations.

Organization of the Spinal Cord

Organization of the Spinal Cord
Author:
Publisher: Elsevier
Total Pages: 297
Release: 1964-01-01
Genre: Medical
ISBN: 0080861350

This volume includes contributions from almost all of the leading neuroanatomists who have in recent years devoted their attention to the spinal cord.

Organization in the Spinal Cord

Organization in the Spinal Cord
Author: A. G. Brown
Publisher: Springer Science & Business Media
Total Pages: 251
Release: 2012-12-06
Genre: Medical
ISBN: 1447113055

The research described in this book arose, in large part, from a sense of frustration. For a number of years I had been studying the physiology of the spinocervical tract, a somatosensory pathway, in the cat's spinal cord. But I did not know, precisely, where the cells of origin of the tract were located and therefore did not know what they looked like or whether there were any correlations between structure and function. It was true that electrophysiolo gical experiments had indicated their probable situation in the dorsal horn, and anatomical work had described the morphology of cells that were likely to give rise to the axons of the tract; but this was not satisfactory. With the publication, by Stretton and Kravitz in 1968, of the Procion Yellow ionophoretic method for intracellular staining, a new tool became available for studying the morphology of physiologically identified neurones. We used the techniques and, although very pleased with the beautiful appearance of the dendritic trees of neurones seen in the fluorescence microscope, we were again frustrated, this time by the inability of Procion Yellow to stain axons for any considerable length. Therefore, P. K. Rose and P. J. Snow and I began to try to develop a method that would stain the axon, together with its collaterals, in addition to the soma and dendrites of an intracellularly re corded neurone.

Anatomy & Physiology

Anatomy & Physiology
Author: Lindsay Biga
Publisher:
Total Pages:
Release: 2019-09-26
Genre:
ISBN: 9781955101158

A version of the OpenStax text

The Spinal Cord

The Spinal Cord
Author: Charles Watson
Publisher: Academic Press
Total Pages: 408
Release: 2009-11-27
Genre: Medical
ISBN: 0080921388

Many hundreds of thousands suffer spinal cord injuries leading to loss of sensation and motor function in the body below the point of injury. Spinal cord research has made some significant strides towards new treatment methods, and is a focus of many laboratories worldwide. In addition, research on the involvement of the spinal cord in pain and the abilities of nervous tissue in the spine to regenerate has increasingly been on the forefront of biomedical research in the past years. The Spinal Cord, a collaboration with the Christopher and Dana Reeve Foundation, is the first comprehensive book on the anatomy of the mammalian spinal cord. Tens of thousands of articles and dozens of books are published on this subject each year, and a great deal of experimental work has been carried out on the rat spinal cord. Despite this, there is no comprehensive and authoritative atlas of the mammalian spinal cord. Almost all of the fine details of spinal cord anatomy must be searched for in journal articles on particular subjects. This book addresses this need by providing both a comprehensive reference on the mammalian spinal cord and a comparative atlas of both rat and mouse spinal cords in one convenient source. The book provides a descriptive survey of the details of mammalian spinal cord anatomy, focusing on the rat with many illustrations from the leading experts in the field and atlases of the rat and the mouse spinal cord. The rat and mouse spinal cord atlas chapters include photographs of Nissl stained transverse sections from each of the spinal cord segments (obtained from a single unfixed spinal cord), detailed diagrams of each of the spinal cord segments pictured, delineating the laminae of Rexed and all other significant neuronal groupings at each level and photographs of additional sections displaying markers such as acetylcholinesterase (AChE), calbindin, calretinin, choline acetlytransferase, neurofilament protein (SMI 32), enkephalin, calcitonin gene-related peptide (CGRP), and neuronal nuclear protein (NeuN). - The text provides a detailed account of the anatomy of the mammalian spinal cord and surrounding musculoskeletal elements - The major topics addressed are: development of the spinal cord; the gross anatomy of the spinal cord and its meninges; spinal nerves, nerve roots, and dorsal root ganglia; the vertebral column, vertebral joints, and vertebral muscles; blood supply of the spinal cord; cytoarchitecture and chemoarchitecture of the spinal gray matter; musculotopic anatomy of motoneuron groups; tracts connecting the brain and spinal cord; spinospinal pathways; sympathetic and parasympathetic elements in the spinal cord; neuronal groups and pathways that control micturition; the anatomy of spinal cord injury in experimental animals - The atlas of the rat and mouse spinal cord has the following features: Photographs of Nissl stained transverse sections from each of 34 spinal segments for the rat and mouse; Detailed diagrams of each of the 34 spinal segments for rat and mouse, delineating the laminae of Rexed and all other significant neuronal groupings at each level. ; Alongside each of the 34 Nissl stained segments, there are additional sections displaying markers such as acetylcholinesterase, calbindin, calretinin, choline acetlytransferase, neurofilament protein (SMI 32), and neuronal nuclear protein (NeuN) - All the major motoneuron clusters are identified in relation to the individual muscles or muscle groups they supply

Development of the Human Spinal Cord

Development of the Human Spinal Cord
Author: Joseph Altman
Publisher: Oxford University Press, USA
Total Pages: 566
Release: 2001
Genre: Developmental neurobiology
ISBN: 9780195144277

There exists a wealth of information about the development of the spinal cord in journal articles and monographs, yet this beautifully illustrated work is the first book devoted to this important topic. Because the developing human spinal cord cannot be subjected to experimental manipulations, the knowledge gained from experimental work in animals is applied here to an interpretation of the time course and mechanisms of spinal cord development in man. The book begins with a review of our current understanding of the structure and functions of the spinal cord. Special reference is made to the phylogeny of the vertebrate spinal cord because the authors' interpretation of the development and organization of the human spinal cord is specifically an evolutionary one. Following a detailed experiment-based account of spinal cord development in the rat, the development of the human spinal cord is described, illustrated and interpreted in separate chapters during three epochs: the first trimester (the embryonic period), the second and third trimesters (the fetal period), and the first year of postnatal life. Special attention is paid to such topics as neurons, and the growth and myelination of the ascending and descending fiber tracts of the spinal cord. The book ends with a correlation of the development of motor behavior with different stages in the morphological development of the human spinal cord during the embryonic, fetal, and postnatal periods. The successive acquisition of voluntary control over different parts of the body during infancy is correlated with the progressive myelination of the corticospinal tract. * The book contains an extensive review of work on spinal cord organization and development throughout the 20th century. * The interpretations are based on experimental studies of spinal cord development in the rat carried out by the authors and their associates. * The histological material on human spinal cord development is the largest ever assembled and reproduced (combining the Carnegie, Minot, and Yakovlev Collections). * The collected material (which varies in quality and some of it has begun to fade) has been digitized and electronically reprocessed for improved reproduction. * Discrete components of the spinal cord and new developments are highlighted by color coding; typically on one side only, leaving the contralateral side untouched to allow the reader to use his own interpretation. * Summary graphs are presented, many in color, to convey important structural relationships, developmental events, or theories. * The authors revive a few forgotten theories and offer several new ones regarding the development and organization of the human spinal cord. Development of the Human Spinal Cord will be of interest to developmental biologists, neuroscientists, embryologists, molecular biologists (those working on stem cell research), pediatric neurologists, pathologists, child and developmental psychologists, and their students and trainees