Optogenetics: A Roadmap

Optogenetics: A Roadmap
Author: Albrecht Stroh
Publisher:
Total Pages: 302
Release: 2018
Genre: Biomedicine
ISBN: 9781493974177

This volume focuses on the optogenetics workflow, and covers topics on viral vectors, targeting strategies, choice on opsins, animal models and readouts, and applications in systems neuroscience. This book shows readers how to identify the critical aspects of each methodological step, and how to determine the necessary level of complexity to address the particular research question. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Comprehensive and cutting-edge, Optogenetics: A Roadmap is a valuable guide for both the optogenetics novices and the experts.

All-Optical Methods to Study Neuronal Function

All-Optical Methods to Study Neuronal Function
Author: Eirini Papagiakoumou
Publisher: Springer Nature
Total Pages: 424
Release: 2023-02-20
Genre: Medical
ISBN: 1071627643

This open access volume provides an overview of the latest methods used to study neuronal function with all-optical experimental approaches, where light is used for both stimulation and monitoring of neuronal activity. The chapters in this book cover topics over a broad range, from fundamental background information in both physiology and optics in the context of all-optical neurophysiology experiments, to the design principles and hardware implementation of optical methods used for photoactivation and imaging. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Comprehensive and cutting-edge, All-Optical Methods to Study Neuronal Function is a valuable resource for researchers in various disciplines such as physics, engineering, and neuroscience. This book will serve as a guide to establish useful references for groups starting out in this field, and provide insight on the optical systems, actuators, and sensors. This is an open access book.

Zebrafish

Zebrafish
Author: James F. Amatruda
Publisher: Springer Nature
Total Pages: 361
Release: 2023-09-05
Genre: Science
ISBN: 1071634011

This fully updated edition introduces new tools, models, and analytic insights that position the zebrafish even more strongly as an engine of discovery for developmental and disease biology. Beginning with a section exploring detailed methods for use of zebrafish to model a variety of human diseases, the book continues by illuminating the key ongoing role of the fish model in studies of the vertebrate nervous system, tools and approaches using zebrafish to study stem cell and regenerative biology, as well as techniques in genetics and genomics. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Zebrafish: Methods and Protocols, Third Edition serves as an invaluable guide to propel advances in developmental biology, disease modeling, and regeneration research using zebrafish and medaka as model systems.

Epigenetics to Optogenetics

Epigenetics to Optogenetics
Author:
Publisher: BoD – Books on Demand
Total Pages: 178
Release: 2022-08-31
Genre: Science
ISBN: 1838809937

Epigenetics, which deals with the study of heritable gene expression that takes place independent of changes in DNA sequence, and optogenetics, which deals with the study of genes expressed under the influence of light, are two emerging areas of study and research that have contributed immensely to our current knowledge of mechanisms and disease processes in humans. These disciplines are interrelated in the broader picture of biology and one can be used to change or modify the other. The complexity of the techniques involved in these disciplines often leads to a lack of proper understanding by researchers from other disciplines and the scientific community at large. As such, this book provides simple and easy-to-follow explanations of some of the most exciting areas of research in these disciplines.

Cell Biology and Translational Medicine, Volume 9

Cell Biology and Translational Medicine, Volume 9
Author: Kursad Turksen
Publisher: Springer Nature
Total Pages: 163
Release: 2020-08-27
Genre: Science
ISBN: 3030549178

Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the ninth volume of a continuing series.

Optogenetics: A Roadmap

Optogenetics: A Roadmap
Author: Albrecht Stroh
Publisher: Humana Press
Total Pages: 302
Release: 2017-10-25
Genre: Medical
ISBN: 9781493974153

This volume focuses on the optogenetics workflow, and covers topics on viral vectors, targeting strategies, choice on opsins, animal models and readouts, and applications in systems neuroscience. This book shows readers how to identify the critical aspects of each methodological step, and how to determine the necessary level of complexity to address the particular research question. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Comprehensive and cutting-edge, Optogenetics: A Roadmap is a valuable guide for both the optogenetics novices and the experts.

The Mathematics of Superoscillations

The Mathematics of Superoscillations
Author: Yakir Aharonov
Publisher: American Mathematical Soc.
Total Pages: 120
Release: 2017-04-25
Genre: Mathematics
ISBN: 1470423243

In the past 50 years, quantum physicists have discovered, and experimentally demonstrated, a phenomenon which they termed superoscillations. Aharonov and his collaborators showed that superoscillations naturally arise when dealing with weak values, a notion that provides a fundamentally different way to regard measurements in quantum physics. From a mathematical point of view, superoscillating functions are a superposition of small Fourier components with a bounded Fourier spectrum, which result, when appropriately summed, in a shift that can be arbitrarily large, and well outside the spectrum. The purpose of this work is twofold: on one hand the authors provide a self-contained survey of the existing literature, in order to offer a systematic mathematical approach to superoscillations; on the other hand, they obtain some new and unexpected results, by showing that superoscillating sequences can be seen of as solutions to a large class of convolution equations and can therefore be treated within the theory of analytically uniform spaces. In particular, the authors will also discuss the persistence of the superoscillatory behavior when superoscillating sequences are taken as initial values of the Schrödinger equation and other equations.