Opiate Receptors and Antagonists

Opiate Receptors and Antagonists
Author: Reginald Dean
Publisher: Springer Science & Business Media
Total Pages: 767
Release: 2009-03-12
Genre: Medical
ISBN: 1597451975

Comprehensive and authoritative, Opioid Receptors and Antagonists: From Bench to Clinic offers neuroscientists, pharmacologists and interested clinicians a unique survey of the extensive and diverse research efforts currently employed with opioid antagonists to develop novel innovative drug therapies. Summarizes the present understanding of the chemistry, pharmacology and molecular biology of opioid receptors and their subtypes Highlights differences and similarities between the opioid pharmacology of animals and human Describes current and potential therapeutic areas for opioid antagonists, including substance abuse, alcohol and ingestive behaviors, behavioral disorders and other medical indications, supported by nonclinical and clinical evidence Focuses on the development of exciting and innovative drug delivery approaches that are being used with opioid antagonists for the above medical indications

Opioids, Bulimia, and Alcohol Abuse & Alcoholism

Opioids, Bulimia, and Alcohol Abuse & Alcoholism
Author: Larry D. Reid
Publisher: Springer Science & Business Media
Total Pages: 392
Release: 2012-12-06
Genre: Medical
ISBN: 1461390001

This text is the written form of the proceedings of a satellite symposium associated with the 1988-meeting of the Society for Neu roscience. The symposium was held 12 November 1988 in the auditor ium of the Addictions Research Foundation, Toronto, Canada. The ac tual writing took place across the months following the symposium. The symposium was sponsored by the Addictions Research Foundation, Toronto, Canada, the National Institute on Alcohol Abuse and Alcoholism, U. S. A. , and Rensselaer, Troy, NY, U. S. A. Du Pont Pharmaceuticals provided some financial assistance. Contributors also received specific support for their own projects and these are ac knowledged at the end of each chapter. The accomplishment of science involves the efforts of many persons and their organizations. That is surely manifest in the work presented here. Modern science is very expensive and, consequently, financial resouces must be developed and distributed wisely. Those who facilitate this basic function have the appreciation of those of us who need the resources to do our work. There are a large number of individuals whose names will not appear in these pages that make sub stantial contributions. We are thankful for their daily contributions. The people who provide the money, those who distribute it, and those who help us do our work have the legitimate expectation that the sci entists who use the resources will use it prudently. We hope that your expectations are fulfilled, and sincerely appreciate your efforts.

Novel Pharmacological Interventions for Alcoholism

Novel Pharmacological Interventions for Alcoholism
Author: Claudio A. Naranjo
Publisher: Springer Science & Business Media
Total Pages: 378
Release: 2012-12-06
Genre: Medical
ISBN: 1461228786

Novel Pharmacological Interventions for Alcoholism identifies priorities for focusing alcoholism and addiction research efforts during the coming years. A number of important issues concerning methodology, mechanisms, clinical evaluation, and pharmaceutical aspects are discussed. This book is also a plea for a greater degree of collaboration among academics, pharmaceutical physicians and scientists, and drug regulators; it demonstrates that progress in understanding and fighting addiction and alcoholism is possible in the foreseeable future.

Recent Developments in Alcoholism

Recent Developments in Alcoholism
Author: Marc Galanter
Publisher: Springer Science & Business Media
Total Pages: 523
Release: 2013-11-22
Genre: Medical
ISBN: 148991742X

'Each topic is covered in sufficient depth, currency, and clarity to be of value to the neophyte and the seasoned researcher/clinician.' --- American Journal of Psychiatry, from a review of a previous volume The current volume addresses a range of issues across this diverse field, including the effects on society, physiology and biochemistry, clinical pathology, and trends in treatment.

Alcohol Abuse Treatment

Alcohol Abuse Treatment
Author: Ronald R. Watson
Publisher: Springer Science & Business Media
Total Pages: 332
Release: 2012-12-06
Genre: Medical
ISBN: 1461203635

A major national goal is to improve the health of the populace while advancing our opportunities to pursue happiness. Simulta neously, there are both increasing health costs and increasing demands that more be accomplished with less financial support. The number of deaths attributable to the consumption of alcohol in the US is about 100,000 per year, and the annual cost of this addiction is over $100 billion. Improved treatment methods can both reduce these costs and improve health by preventing the continued exposure of abusers to the toxic effects of alcohol. This third volume of Drug and Alcohol Abuse Reviews focuses on the strategies currently thought best for the treatment of alcohol and tobacco abuse. A variety of approaches to treating alcohol abuse employ those psychosocial factors that are known to influence alcohol use in youth and adults. Pharmacotherapy has also been evaluated at the National Institute of Alcohol Abuse and Alcoholism by leaders in alcohol treatment research. One key review investigates forming a developmental framework for the treatment of adolescent alcohol abusers, a major challenge. Although the main emphasis is on the treatment of alcoholism, a major cofactor for many drug users is nicotine (tobacco) addiction, whose treatment is also reviewed. And the roles of learning and outpatient services are shown to affect treatment significantly. Thus, the problems confronted and solutions used in alcohol abuse treatment have here been analyzed in concise reviews that provide evidence for today's best hypoth eses and conclusions.

Treatment of Eating Disorders

Treatment of Eating Disorders
Author: Margo Maine
Publisher: Academic Press
Total Pages: 529
Release: 2010-09-08
Genre: Psychology
ISBN: 0123756693

Eating disorders (EDs) affect at least 11 million people in the United States each year and spread across age, race, ethnicity and socio-economic class. While professional literature on the subject has grown a great deal in the past 30 years, it tends to be exclusively research-based and lacking expert clinical commentary on treatment. This volume focuses on just such commentary, with chapters authored by both expert clinicians and researchers. Core issues such as assessment and diagnosis, the correlation between EDs and weight and nutrition, and medical/psychiatric management are discussed, as are the underrepresented issues of treatment differences based on gender and culture, the applications of neuroscience, EDNOS, comorbid psychiatric disorders and the impact of psychiatric medications. This volume uniquely bridges the gap between theoretical findings and actual practice, borrowing a bench-to-bedside approach from medical research. - Includes real-world clinical findings that will improve the level of care readers can provide, consolidated in one place - Underrepresented issues such as gender, culture, EDNOS and comorbidity are covered in full - Represents outstanding scholarship, with each chapter written by an expert in the topic area

The Cure for Alcoholism

The Cure for Alcoholism
Author: Roy Eskapa
Publisher: BenBella Books, Inc.
Total Pages: 369
Release: 2012-10-23
Genre: Psychology
ISBN: 1937856143

Finally, there is a cure for alcoholism. This is the first step. Featuring new and updated information and studies, including an introduction by actress Claudia Christian, the second edition of The Cure for Alcoholism delivers exactly what millions of alcoholics and families of alcoholics have been hoping for: a painless, dignified, and medically proven cure for their addiction. Backed by 82 clinical trials and research that extends back to 1964, The Sinclair Method deploys an opiate-blocking medication in a very specific way—in combination with ongoing drinking—to extinguish the addictive "software" in the brain. The de-addiction process rolls back the addictive mechanism in the brain to its original pre-addicted state—before the first drink was consumed, making this program an actual cure for alcoholism. Drs. Roy Eskapa and David Sinclair of The Sinclair Method have put together a sound scientific book that proves that with this particular method, alcoholism can be cured in more than 78 percent of patients. What's more, the treatment avoids the dangerous withdrawal symptoms, allowing patients to detox gradually and safely while they are still drinking. This removes the need for expensive and unpleasant inpatient rehabilitation programs. Actual drinking levels and cravings automatically decrease until control over alcohol is restored. The bottom line is that patients can control their drinking or stop altogether with the simple yet powerful process outlined in The Cure for Alcoholism. Including a new introduction by actress Claudia Christian about The Sinclair Method's impact on her life, updated trial information, and a letter explaining the treatment that can be given to doctors by patients, The Cure for Alcoholism is a revolutionary book for anyone who wants to gain control over drinking.

Alcohol in Health and Disease

Alcohol in Health and Disease
Author: Dharam Agarwal
Publisher: CRC Press
Total Pages: 656
Release: 2001-06-01
Genre: Medical
ISBN: 0203902173

This volume, based on presentations from the symposium on the health effects of alcohol held in Titisee, Germany, examines the physical and psychological consequences of alcohol use and abuse, and considers environmental and ethnic factors that lead to addiction and dependence. Discusses epidemiological studies that show the influence of light to moderate intake of alcoholic beverages on coronary heart disease. Featuring contributions from nearly 60 internationally recognized and respected authors, and over 2900 references for further investigation of the subject, Alcohol in Health and Disease analyzes biochemical, pharmacogenetic, and pathologic disturbances that follow acute and chronic ingestion of alcohol; describes complications that arise from social, biological, and environmental factors; examines alcohol metabolic genes and their role in alcohol sensitivity, drinking habits, and dependence; spotlights hepatic and nutritional disorders associated with alcoholism; considers the relationship of alcohol to cancer; debates the French paradox and more. Covering a multitude of disciplines, including molecular biochemistry, genetics, epidemiology, pathophysiology, neurobiology, and cardiology, Alcohol in Health and Disease is a critical reference for addiction psychiatrists, neuropsychopharmacologists, psychologists, geneticists, toxicologists, biochemists, environmental and public health scientists, health policy makers, social workers, counselors, and graduate and medical school students in these disciplines.

The Pharmacology of Alcohol Abuse

The Pharmacology of Alcohol Abuse
Author: Henry R. Kranzler
Publisher: Springer Science & Business Media
Total Pages: 558
Release: 2012-12-06
Genre: Medical
ISBN: 3642784356

The subject of the book is the pharmacology of ethanol. It brings together the work of both basic and clinical investigators in the pharmacology of alcohol and alcohol abuse. The major focus is on the integration of findings from different levels of analysis, together with a discussion of recent insights from molecular biology in terms of their relevance for understanding ethanol's effects and the implications for the development of medications. Comprehensive in its scope, this book provides an up-to-date, in-depth treatment of the field, with particular emphasis on the integration of research findings from diverse approaches and how these findings might influence future investigations.

Study Guide to Substance Abuse Treatment

Study Guide to Substance Abuse Treatment
Author: Robert E. Hales
Publisher: American Psychiatric Pub
Total Pages: 264
Release: 2008
Genre: Medical
ISBN: 1585623393

Study Guide to Substance Abuse Treatment is a question-and-answer companion that allows you to evaluate your mastery of the subject matter as you progress through The American Psychiatric Publishing Textbook of Substance Abuse Treatment, Fourth Edition. The Study Guide is made up of 292 questions divided into 49 individual quizzes of 4-9 questions each that correspond to chapters in the Textbook. Questions are followed by an Answer Guide that references relevant text (including the page number) in the Textbook to allow quick access to needed information. Each answer is accompanied by a discussion that not only addresses the correct response but also explains why other responses are not correct. The Study Guide's companion, the fourth edition of The American Psychiatric Publishing Textbook of Substance Abuse Treatment has been fully updated to present the most current scientific and clinical information on a wide range of substance use disorders, from tobacco and alcohol to methamphetamine and "club drug" abuse. The text offers a comprehensive view of the basic science and psychology underlying addiction as well as extensive coverage of all treatment approaches and specialty topics. Highlights of this new edition include chapters on the biology and clinical management for each of the drug categories; new material on the role of buprenorphine in treating opioid addiction; extensive coverage of cognitive-behavioral therapy, motivational enhancement, and contingency management; and new research on the role of 12-step programs in addiction treatment.