One Renegade Cell

One Renegade Cell
Author: Robert A Weinberg
Publisher: Basic Books
Total Pages: 180
Release: 2008-08-04
Genre: Science
ISBN: 0786724013

Cancer research has reached a major turning point. The quality and quantity of information gathered about this disease in the past twenty years has revolutionized our understanding of its origins and behavior. No one is better qualified to comment on these dramatic leaps forward than molecular biologist Robert A. Weinberg, director of one of the leading cancer research centers in the world. In One Renegade Cell , Weinberg presents an accessible and state-of-the-art account of how the disease begins and how, one day, it will be cured. Weinberg tells how the roots of cancer were uncovered in 1909 and when the first cancer-causing virus was discovered. He then moves forward to the discovery of the role of chemical carcinogens and radiation in triggering cancer, and relates the remarkable story of the discoveries of oncogenes and tumor suppressor genes, the master controllers of normal and malignant cell proliferation. This book, which presumes little prior knowledge of biology, describes the revolution in biomedical research that has finally uncovered the forces driving malignant growth. Drawing on insights that simply were not available until recently, the discoveries presented in One Renegade Cell have already begun to profoundly alter the way that we diagnose and treat human cancers.

Renegade

Renegade
Author: J. A. Souders
Publisher: Macmillan
Total Pages: 370
Release: 2012-11-13
Genre: Juvenile Fiction
ISBN: 0765332450

First in a pulse-pounding new young adult SF series with a deadly psychological twist.

The Philadelphia Chromosome: A Genetic Mystery, a Lethal Cancer, and the Improbable Invention of a Lifesaving Treatment

The Philadelphia Chromosome: A Genetic Mystery, a Lethal Cancer, and the Improbable Invention of a Lifesaving Treatment
Author: Jessica Wapner
Publisher: The Experiment, LLC
Total Pages: 345
Release: 2014-04-08
Genre: Health & Fitness
ISBN: 1615191658

One of The Wall Street Journal’s 10 Best Nonfiction Books of the Year Philadelphia, 1959: A scientist scrutinizing a single human cell under a microscope detects a missing piece of DNA. That scientist, David Hungerford, had no way of knowing that he had stumbled upon the starting point of modern cancer research— the Philadelphia chromosome. It would take doctors and researchers around the world more than three decades to unravel the implications of this landmark discovery. In 1990, the Philadelphia chromosome was recognized as the sole cause of a deadly blood cancer, chronic myeloid leukemia, or CML. Cancer research would never be the same. Science journalist Jessica Wapner reconstructs more than forty years of crucial breakthroughs, clearly explains the science behind them, and pays tribute—with extensive original reporting, including more than thirty-five interviews—to the dozens of researchers, doctors, and patients with a direct role in this inspirational story. Their curiosity and determination would ultimately lead to a lifesaving treatment unlike anything before it. The Philadelphia Chromosome chronicles the remarkable change of fortune for the more than 70,000 people worldwide who are diagnosed with CML each year. It is a celebration of a rare triumph in the battle against cancer and a blueprint for future research, as doctors and scientists race to uncover and treat the genetic roots of a wide range of cancers.

Rebel Cell

Rebel Cell
Author: Kat Arney
Publisher: BenBella Books
Total Pages: 256
Release: 2020-10-20
Genre: Medical
ISBN: 1950665518

Why do we get cancer? Is it our modern diets and unhealthy habits? Chemicals in the environment? An unwelcome genetic inheritance? Or is it just bad luck? The answer is all of these and none of them. We get cancer because we can't avoid it—it's a bug in the system of life itself. Cancer exists in nearly every animal and has afflicted humans as long as our species has walked the earth. In Rebel Cell: Cancer, Evolution, and the New Science of Life's Oldest Betrayal, Kat Arney reveals the secrets of our most formidable medical enemy, most notably the fact that it isn't so much a foreign invader as a double agent: cancer is hardwired into the fundamental processes of life. New evidence shows that this disease is the result of the same evolutionary changes that allowed us to thrive. Evolution helped us outsmart our environment, and it helps cancer outsmart its environment as well—alas, that environment is us. Explaining why "everything we know about cancer is wrong," Arney, a geneticist and award-winning science writer, guides readers with her trademark wit and clarity through the latest research into the cellular mavericks that rebel against the rigid biological "society" of the body and make a leap towards anarchy. We need to be a lot smarter to defeat such a wily foe—smarter even than Darwin himself. In this new world, where we know that every cancer is unique and can evolve its way out of trouble, the old models of treatment have reached their limits. But we are starting to decipher cancer's secret evolutionary playbook, mapping the landscapes in which these rogue cells survive, thrive, or die, and using this knowledge to predict and confound cancer's next move. Rebel Cell is a story about life and death, hope and hubris, nature and nurture. It's about a new way of thinking about what this disease really is and the role it plays in human life. Above all, it's a story about where cancer came from, where it's going, and how we can stop it.

Racing to the Beginning of the Road

Racing to the Beginning of the Road
Author: Robert Allan Weinberg
Publisher: W H Freeman & Company
Total Pages: 274
Release: 1998-01-01
Genre: Medical
ISBN: 9780716732839

Details the latest advances in cancer research and the politics involved, and examines the history of cancer theories

Life Itself

Life Itself
Author: Boyce Rensberger
Publisher: Oxford University Press, USA
Total Pages: 314
Release: 1996
Genre: Science
ISBN:

In Amazing Life, Boyce Rensberger takes readers to the frontlines of cell research with some of the brightest investigators in molecular, cellular, and developmental biology. The hottest topics in biomedical research are covered.

The Emperor of All Maladies

The Emperor of All Maladies
Author: Siddhartha Mukherjee
Publisher: Simon and Schuster
Total Pages: 624
Release: 2011-08-09
Genre: Health & Fitness
ISBN: 1439170916

Winner of the Pulitzer Prize and a documentary from Ken Burns on PBS, this New York Times bestseller is “an extraordinary achievement” (The New Yorker)—a magnificent, profoundly humane “biography” of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

Renegade

Renegade
Author: Mark E. Smith
Publisher: Penguin UK
Total Pages: 256
Release: 2014-09-25
Genre: Biography & Autobiography
ISBN: 0241972434

Still going after thirty years, The Fall are one of the most distinctive British bands, their music - odd,spare, cranky and repetitious - an acknowledged influence on The Smiths, The Happy Mondays, Nirvana and Franz Ferdinand. And Mark E. Smith IS The Fall - 47 members have come and gone over the years yet he remains its charismatic leader, a professional outsider and all-round enemy of compromise, a true enigma. There have been a number of biographies of the legendary Smith, but this is the first time he has opened up in a full autobiography. For the first time we get to hear his full, candid take on the ups and downs of a band as notorious for its in-house fighting as for its great music; and on a life that has endured prison in America, drugs, bankruptcy, divorce, and the often bleak results of a legendary thirst.

Renegade Dreams

Renegade Dreams
Author: Laurence Ralph
Publisher: University of Chicago Press
Total Pages: 273
Release: 2014-09-15
Genre: Social Science
ISBN: 022603271X

Inner city communities in the US have become junkyards of dreams, to quote Mike Daviswastelands where gangs package narcotics to stimulate the local economy, gunshots occur multiple times on any given day, and dreams of a better life can fade into the realities of poverty and disability. Laurence Ralph lived in such a community in Chicago for three years, conducting interviews and participating in meetings with members of the local gang which has been central to the community since the 1950s. Ralph discovered that the experience of injury, whether physical or social, doesn t always crush dreams into oblivion; it can transform them into something productive: renegade dreams. The first part of this book moves from a critique of the way government officials, as opposed to grandmothers, have been handling the situation, to a study of the history of the historic Divine Knights gang, to a portrait of a duo of gang members who want to be recognized as authentic rappers (they call their musical style crack music ) and the difficulties they face in exiting the gang. The second part is on physical disability, including being wheelchair bound, the prevalence of HIV/AIDS among heroin users, and the experience of brutality at the hands of Chicago police officers. In a final chapter, The Frame, Or How to Get Out of an Isolated Space, Ralph offers a fresh perspective on how to understand urban violence. The upshot is a total portrait of the interlocking complexities, symbols, and vicissitudes of gang life in one of the most dangerous inner city neighborhoods in the US. We expect this study will enjoy considerable readership, among anthropologists, sociologists, and other scholars interested in disability, urban crime, and race."

Genes and the Biology of Cancer

Genes and the Biology of Cancer
Author: Harold Varmus
Publisher: Times Books
Total Pages: 214
Release: 1993-01-01
Genre: Medical
ISBN: 9780716750376

Discusses advances in cancer research and shows how research into the causes of cancer have led to a greater understanding of the normal biological functioning of cells