The Complete Spleen

The Complete Spleen
Author: Anthony J. Bowdler
Publisher: Springer Science & Business Media
Total Pages: 334
Release: 2001-12-04
Genre: Medical
ISBN: 1592591248

In this thoroughly revised and updated second edition, a panel of distinguished clinical researchers from around the world takes stock of the wealth of new knowledge about the human spleen and applies it to the pathology and treatment of splenic diseases. This much enriched understanding encompasses the spleen's complex role in immunological defense, the recently defined function of particulate filtration by the spleen, and the structural basis for the functions of the spleen, most particularly the microvasculature around which it is organized. Among the diseases and disorders of the spleen considered in detail are splenomegaly, the consequences and management of hyper- and hyposplenism, and "dilutional anemia." Recent advances in splenic surgery are also reviewed, especially those techniques intended to preserve at least partial function while removing the greater part of the organ.

Hemopoietic System

Hemopoietic System
Author: Thomas C. Jones
Publisher: Springer Science & Business Media
Total Pages: 644
Release: 2012-12-06
Genre: Medical
ISBN: 3642841104

The International Life Sciences Institute (ILSI) was estab lished in 1978 to stimulate and support scientific research and educational programs related to nutrition, toxicology, and food safety, and to encourage cooperation in these programs among scientists in universities, industry, and government agencies to assist in the resolution of health and safety issues. To supplement and enhance these efforts, ILSI has made a major commitment to supporting programs to harmon ize toxicologic testing, to advance a more uniform inter pretation of bioassay results worldwide, to promote a common understanding of lesion classifications, and to encourage wide discussion of these topics among scien tists. The Monographs on the Pathology of Laboratory Ani mals are designed to facilitate communication among those involved in the safety testing of foods, drugs, and chemicals. The complete set will cover all organ systems and is intended for use by pathologists, toxicologists, and others concerned with evaluating toxicity and carcinogen icity studies. The international nature of the project - as reflected in the composition of the editorial board and the diversity of the authors and editors - strengthens our ex pectations that understanding and cooperation will be im proved worldwide through the series. Alex Malaspina President International Life Sciences Institute Preface This book, on the hemopoietic system, is the eighth volume of a set prepared under the sponsorship of the International Life Sciences In stitute (ILSI).

The Making of Mr Gray's Anatomy

The Making of Mr Gray's Anatomy
Author: Ruth Richardson
Publisher: OUP Oxford
Total Pages: 338
Release: 2008-10-23
Genre: Medical
ISBN: 0191564648

Gray's Anatomy is probably one of the most iconic scientific books ever published: an illustrated textbook of anatomy that is still a household name 150 years since its first edition, known for its rigorously scientific text, and masterful illustrations as beautiful as they are detailed. The Making of Mr Gray's Anatomy tells the story of the creation of this remarkable book, and the individuals who made it happen: Henry Gray, the bright and ambitious physiologist, poised for medical fame and fortune, who was the book's author; Carter, the brilliant young illustrator, lacking Gray's social advantages, shy and inclined to religious introspection; and the publishers - Parkers, father and son, the father eager to employ new technology, the son part of a lively circle of intellectuals. It is the story of changing attitudes in the mid-19th century; of the social impact of science, the changing status of medicine; of poverty and class; of craftsmanship and technology. And it all unfolds in the atmospheric milieu of Victorian London - taking the reader from the smart townhouses of Belgravia, to the dissection room of St George's Hospital, and to the workhouses and mortuaries where we meet the friendless poor who would ultimately be immortalised in Carter's engravings. Alongside the story of the making of the book itself, Ruth Richardson reflects on what made Gray's Anatomy such a unique intellectual, artistic, and cultural achievement - how it represented a summation of a long half century's blossoming of anatomical knowledge and exploration, and how it appeared just at the right time to become the 'Doctor's Bible' for generations of medics to follow.

The Exocrine Pancreas

The Exocrine Pancreas
Author: Stephen Pandol
Publisher: Morgan & Claypool Publishers
Total Pages: 66
Release: 2011
Genre: Medical
ISBN: 1615041389

The secretions of the exocrine pancreas provide for digestion of a meal into components that are then available for processing and absorption by the intestinal epithelium. Without the exocrine pancreas, malabsorption and malnutrition result. This chapter describes the cellular participants responsible for the secretion of digestive enzymes and fluid that in combination provide a pancreatic secretion that accomplishes the digestive functions of the gland. Key cellular participants, the acinar cell and the duct cell, are responsible for digestive enzyme and fluid secretion, respectively, of the exocrine pancreas. This chapter describes the neurohumoral pathways that mediate the pancreatic response to a meal as well as details of the cellular mechanisms that are necessary for the organ responses, including protein synthesis and transport and ion transports, and the regulation of these responses by intracellular signaling systems. Examples of pancreatic diseases resulting from dysfunction in cellular mechanisms provide emphasis of the importance of the normal physiologic mechanisms.