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| Author | : OECD |
| Publisher | : OECD Publishing |
| Total Pages | : 95 |
| Release | : 2014-09-03 |
| Genre | : |
| ISBN | : 9264085491 |
This Detailed Review Paper describes some endocrine pathways that have been shown to be susceptible to environmental endocrine disruption and whose disruption could contribute to increasing incidents of some disorders in humans and wildlife populations.
| Author | : OECD |
| Publisher | : OECD Publishing |
| Total Pages | : 213 |
| Release | : 2012-08-21 |
| Genre | : |
| ISBN | : 9264221352 |
This paper provides methods for both the mechanistic evaluation of the action of Endocrine Disrupter Chemicals (EDCs).
| Author | : OECD |
| Publisher | : OECD Publishing |
| Total Pages | : 692 |
| Release | : 2018-09-03 |
| Genre | : |
| ISBN | : 9264304746 |
This guidance document was originally published in 2012 and updated in 2018 to reflect new and updated OECD test guidelines, as well as reflect on scientific advances in the use of test methods and assessment of the endocrine activity of chemicals.
| Author | : OECD |
| Publisher | : OECD Publishing |
| Total Pages | : 313 |
| Release | : 2002-05-10 |
| Genre | : |
| ISBN | : 926407838X |
This documents servies as the basis for the first step in the consideration and development of OECD Test Guidelines for the testing of chemicals for endocrine-disrupting effects.
| Author | : OECD |
| Publisher | : OECD Publishing |
| Total Pages | : 106 |
| Release | : 2004-11-01 |
| Genre | : |
| ISBN | : 9264079149 |
This Detailed Review Paper (DRP) provides the current state-of-the-knowledge in the area of amphibian metamorphosis with the view to use amphibian metamorphosis as a model for the detection of chemicals affecting the thyroid axis in vertebrates.
| Author | : OECD |
| Publisher | : OECD Publishing |
| Total Pages | : 148 |
| Release | : 2014-07-11 |
| Genre | : |
| ISBN | : 9264274715 |
This scoping document aims at bringing forward relevant in vitro and ex vivo thyroid assays to the attention of OECD member countries, to provide recommendations for their development/use, and also, to identify aspects/blocks of the thyroid signalling pathways that are not covered and would ...
| Author | : OECD |
| Publisher | : OECD Publishing |
| Total Pages | : 182 |
| Release | : 2014-09-03 |
| Genre | : |
| ISBN | : 9264221468 |
This paper reviews what is known about the responses of molluscs to endocrine disrupting chemicals (EDCs), to consider whether it would be desirable and feasible to standardise mollusc-based partial- and full-lifecycle tests that are sensitive to EDCs and to other chemicals.
| Author | : OECD |
| Publisher | : OECD Publishing |
| Total Pages | : 170 |
| Release | : 2004-11-01 |
| Genre | : |
| ISBN | : 9264079157 |
This Detailed Review Paper (DRP) is intended to provide the current state-of-the-knowledge in the area of fish screening assays for chemicals active at the endocrine level on the reproductive system of test animals.
| Author | : OECD |
| Publisher | : OECD Publishing |
| Total Pages | : 206 |
| Release | : 2018-12-10 |
| Genre | : |
| ISBN | : 9264304797 |
In the past several decades, there has been a substantial increase in the availability of in vitro test methods for evaluating chemical safety in an international regulatory context. To foster confidence in in vitro alternatives to animal testing, the test methods and conditions under which ...
| Author | : OECD |
| Publisher | : OECD Publishing |
| Total Pages | : 524 |
| Release | : 2014-09-03 |
| Genre | : |
| ISBN | : 9264221417 |
This document is a tool to support regulatory authorities’ decisions on the hazard of specific chemicals when they receive test results from a Test Guideline (TG) or draft TG for the screening/testing of chemicals for endocrine disrupting properties.
