Nutrition Exercise And Epigenetics Ageing Interventions
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| Author | : Byung Pal Yu |
| Publisher | : Springer |
| Total Pages | : 279 |
| Release | : 2015-02-11 |
| Genre | : Medical |
| ISBN | : 3319148303 |
This book focuses on the three most important aspects of ageing research: nutrition, physical exercise and epigenetics. The contributors discuss ways that age-related epigenetic imprints such as DNA methylation and histone acetylation are modified by these two interventions. The emphasis on epigenetics helps to illuminate the underlying mechanisms of anti-ageing interventions, as ageing and disease are predominately epigenetic phenomena. Among the highlights are chapter-length discussion of such topics as: how anti-inflammatory action of calorie restriction underlies the retardation of ageing and age-related diseases (Chapter 3); epigenetic modification of gene expression by exercise (Chapter 5); the role of functional foods and their bioactive components in bone health (Chapter 8); and an account of the first decade of a study of calorie restriction in nonhuman primates, conducted by the National Institute on Ageing.
| Author | : Trygve O. Tollefsbol |
| Publisher | : Springer Science & Business Media |
| Total Pages | : 462 |
| Release | : 2009-11-11 |
| Genre | : Medical |
| ISBN | : 1441906398 |
Recent studies have indicated that epigenetic processes may play a major role in both cellular and organismal aging. These epigenetic processes include not only DNA methylation and histone modifications, but also extend to many other epigenetic mediators such as the polycomb group proteins, chromosomal position effects, and noncoding RNA. The topics of this book range from fundamental changes in DNA methylation in aging to the most recent research on intervention into epigenetic modifications to modulate the aging process. The major topics of epigenetics and aging covered in this book are: 1) DNA methylation and histone modifications in aging; 2) Other epigenetic processes and aging; 3) Impact of epigenetics on aging; 4) Epigenetics of age-related diseases; 5) Epigenetic interventions and aging: and 6) Future directions in epigenetic aging research. The most studied of epigenetic processes, DNA methylation, has been associated with cellular aging and aging of organisms for many years. It is now apparent that both global and gene-specific alterations occur not only in DNA methylation during aging, but also in several histone alterations. Many epigenetic alterations can have an impact on aging processes such as stem cell aging, control of telomerase, modifications of telomeres, and epigenetic drift can impact the aging process as evident in the recent studies of aging monozygotic twins. Numerous age-related diseases are affected by epigenetic mechanisms. For example, recent studies have shown that DNA methylation is altered in Alzheimer’s disease and autoimmunity. Other prevalent diseases that have been associated with age-related epigenetic changes include cancer and diabetes. Paternal age and epigenetic changes appear to have an effect on schizophrenia and epigenetic silencing has been associated with several of the progeroid syndromes of premature aging. Moreover, the impact of dietary or drug intervention into epigenetic processes as they affect normal aging or age-related diseases is becoming increasingly feasible.
| Author | : Ronald Ross Watson |
| Publisher | : Academic Press |
| Total Pages | : 516 |
| Release | : 2012-10-23 |
| Genre | : Health & Fitness |
| ISBN | : 0123971551 |
Bioactive Food as Dietary Interventions for the Aging Population presents scientific evidence of the impact bioactive foods can have in the prevention and mediation of age related diseases. Documents foods that can affect metabolic syndrome and ways the associated information could be used to understand other diseases, which share common etiological pathways.
| Author | : Kara N. Fitzgerald |
| Publisher | : Hachette Go |
| Total Pages | : 388 |
| Release | : 2022-01-18 |
| Genre | : Health & Fitness |
| ISBN | : 0306924854 |
Based on the groundbreaking study that shaved three years off a subjects' age in just eight weeks, discover a proven, accessible plan to prevent diseases and reduce your biological age. It’s true: getting older is inevitable and your chronological age can only move in one direction. But you also have a biological age, which scientists can measure by assessing how your genes are expressed through epigenetics. Exciting new research shows that your bio age can actually move in reverse—and Dr. Kara Fitzgerald’s groundbreaking, rigorous clinical trial proved it’s possible. By eating delicious foods and establishing common-sense lifestyle practices that positively influence genetic expression, study participants reduced their bio age by just over three years in only eight weeks! Now Dr. Fitzgerald shares the diet and lifestyle plan that shows you how to influence your epigenetics for a younger you. In Younger You you’ll learn: It’s not your genetics that determines your age and level of health, it’s your epigenetics How DNA methylation powerfully influences your epigenetic expression The foods and lifestyle choices that most affect DNA methylation Simple swaps to your daily routines that will add years to your life The full eating and lifestyle program, with recipes and meal plans, to reduce your bio age and increase vitality How to take care of your epigenetic expression at every life stage, from infancy through midlife and your later decades We don’t have to accept a descent into disease and unwellness as we age as inevitable: when you reduce bio age you reduce your odds of developing all the major diseases, including diabetes, cancer, and dementia. With assessment tools for determining your bio age, recipes, and plans for putting it all into practice,Younger You helps you repair years of damage, ward off chronic disease, and optimize your health—for years to come.
| Author | : Irfan Rahman |
| Publisher | : Academic Press |
| Total Pages | : 383 |
| Release | : 2013-09-03 |
| Genre | : Technology & Engineering |
| ISBN | : 0123978076 |
The book provides a comprehensive overview to understanding the integrated impact of the concepts of cellular and molecular aspects, models, environmental factors, and lifestyle involved in premature aging. Additionally, it examines how functional food, dietary nutraceuticals or pharmacological compounds can reverse inflammation and premature aging based on personalized medicine. This book is a valuable resource for health professionals, scientists and researchers, nutritionists, health practitioners, students and for all those who wish to broaden their knowledge in the allied field. - Includes models of aging, including worm, mouse and human - Explores the relationship of inflammation with diseases, including ocular health, Alzheimer's and Parkinson's disease, and muscle health - Encompasses a variety of lifestyle impacts, including diet, exercise and nutrition - Includes suggested nutritional interventions
| Author | : Stuart M Raleigh |
| Publisher | : Academic Press |
| Total Pages | : 322 |
| Release | : 2021-07-13 |
| Genre | : Medical |
| ISBN | : 0128209372 |
Epigenetics of Exercise and Sports: Concepts, Methods, and Current Research explains fundamental epigenetic processes and how these are altered by exercise and sports. After a brief review of fundamental epigenetic biology, this all-new volume in the Translational Epigenetics series offers step-by-step instruction in how epigenetic factors are investigated for their influence over exercise related traits of human physiology, disease, and injury. The current state of knowledge in the field and recent findings are discussed in-depth, illuminating how exercise and sports performance may epigenetically modify our physiology, disease and injury risks, and how this knowledge can be applied in personalized exercise approaches, diagnostics, and treatment. This book also explores the shortcomings of explaining exercise related phenomena using only genomics and traditional biochemical techniques, setting the scene for a paradigm shift in exercise biology. In addition, over a dozen international specialists contribute chapters on exercise and sports epigenetics, and their influence over metabolism, obesity, aging, immunity, and neurological disease, as well as the epigenetic impacts of concussions and sports doping. A concluding chapter discusses ongoing themes in the field and outlooks for future research. - Thoroughly examines fundamental concepts in exercise and sports epigenetics, methods for new research, and known impacts for human physiology, disease, and clinical outcomes - Discusses exercise and sports epigenetics in relation to metabolism, obesity, aging, immunity, and neurological disease, concussion, and sports doping, among other topics - Includes preliminary information on exercise epigenetics and covid-19 infection - Features chapter contributions from international experts in the field
| Author | : |
| Publisher | : Elsevier |
| Total Pages | : 0 |
| Release | : 2025-03-01 |
| Genre | : Medical |
| ISBN | : 0443155739 |
Nutritional Epigenomics, Second Edition, a volume in the Translational Epigenetics, offers a comprehensive overview of nutritional epigenomics as a mode of study, along with nutrition's role in the epigenomic regulation of disease, health, and developmental processes. Here, an expert team of international contributors introduces readers to nutritional epigenomic regulators of gene expression, our diet's role in epigenomic regulation of disease and disease inheritance, caloric restriction and exercise as they relate to recent epigenomic findings, and the influence of nutritional epigenomics over circadian rhythms, aging and longevity, and fetal health and development, among other processes. Disease specific chapters address metabolic disease (obesity and diabetes), cancer, and neurodegeneration, among other disorders. Diet-gut microbiome interactions in the epigenomic regulation of disease are also discussed, as is the role of micronutrients and milk miRNAs in epigenetic regulation. Finally, chapter authors examine ongoing discussions of race and ethnicity in the social-epigenomic regulation of health and disease. This new edition has been fully updated to reflect current research in the field. All-new and revised chapters consider the social and physical environments associated with DNA methylation, the relationship between nutritional epigenomics and inflammation, chromatin modifications and non-coding RNAs, as well as the epigenetic influence of food bioactives in metabolic disease and cancer, empowering researchers to employ nutritional epigenomics approaches in new, field-driving studies and applications. - Empowers researchers and clinicians to employ nutritional epigenomics approaches in their own research and practice - Offers a full grounding in epigenetic reprogramming and nutritional intervention in the treatment and prevention of disease, as informed by population-based studies - Concludes with clinical recommendations and practical applications related to nutrition and lifestyle choices - Fully considers recent advances in the field, including new research into chromatin modifications, non-coding RNAs, and fiber regulation of the microbiome and human health - Features chapter contributions from international leaders in the field
| Author | : Dominique Meynial-Denis |
| Publisher | : CRC Press |
| Total Pages | : 384 |
| Release | : 2019-11-20 |
| Genre | : Medical |
| ISBN | : 0429531974 |
Sarcopenia: Molecular, Cellular, and Nutritional Aspects describes the progressive loss of skeletal muscle mass and strength, defined by Rosenberg in 1997 as a hallmark of aging and referred to as “sarcopenia.” As life expectancy continues to increase worldwide, sarcopenia has become a major public health issue. The condition worsens in the presence of chronic diseases accelerating its progression. Sarcopenia is not considered to be “a process of normative aging” but according to the International Classification of Disease, Tenth Revision, Clinical Modification (ICD-10-CM), as a disease. As sarcopenia is an ineluctable process, prevention and management are the only options to promote healthy aging; these actions should perhaps be taken during youth. Included in this book: · Features essential information on sarcopenia, its current definition, and molecular and cellular aspects of this disease · Discusses the development of physical frailty, a complication of sarcopenia, and predicts its occurrence in the older population · Presents alterations in muscle protein turnover and mitochondrial dysfunction in the aging process · Provides data on the negative involvement of sarcopenia in certain chronic diseases · Describes presbyphagia or age-related changes in the swallowing mechanism in older people · Details possible strategies to combat muscle wasting in healthy older adults and their limits This book features information collected from pioneers or experts on human aging from around the globe, including Europe, Brazil, Canada, Japan and the United States. It is a valuable source of information for nutritional scientists, medical doctors, sports scientists, food scientists, dietitians, students in these fields, and for anyone interested in nutrition. We hope this book provides a better understanding of sarcopenia which inevitably occurs with aging without weight loss. Moreover, this book will supply information outlining strategies to prevent or limit muscle wasting due to normal aging in order to promote successful aging.
| Author | : Dong-Hwa Shin |
| Publisher | : CRC Press |
| Total Pages | : 249 |
| Release | : 2022-09-19 |
| Genre | : Medical |
| ISBN | : 1000635139 |
The Republic of Korea (ROK) is projected by 2030 to have the longest living population compared to any nation on earth. A girl born in the ROK in 2030 will live up to 90.8 years on average. What are the reasons for this improvement in longevity? Among many insights for longevity among the people of the ROK is the diverse Korean ethnic diet with roots in a traditional diet that has been preserved for centuries. Korean Food Systems: Secrets of the K-Diet for Healthy Aging provides an integrated and holistic approach towards the understanding how food systems of the ROK and experiences of the last 60-plus years has been sustained by traditions and ecology integrated with contemporary advances in technology and the economy. Key Features: Discusses the rationale and basis of food systems, traditions of healthy eating, and healthy aging in the Korean population and why by 2030 they will be the longest living population on the planet Reflects on the role of historical, cultural, and traditional food and dietary concepts of Korea and how they have influenced healthy eating habits, contributing to health and longevity Discusses the relevance of the modern genetic concepts of nutrigenomics and epigenetics, metabolic concepts such as circulation, and food concepts such as fermented and functional foods in advancing healthy food concepts and longevity Provides insights how a large population can advance an integrated holistic food-based approach to longevity and wellness As a collaboration between various outstanding authors, the insights from this book can provide global examples to align similar approaches and policies in other countries in different ecologies of planet earth.
| Author | : Graham Music |
| Publisher | : Psychology Press |
| Total Pages | : 381 |
| Release | : 2016-10-21 |
| Genre | : Psychology |
| ISBN | : 1317326547 |
This new edition of the bestselling text, Nurturing Natures, provides an indispensable synthesis of the latest scientific knowledge about children’s emotional development. Integrating a wealth of both up-to-date and classical research from areas such as attachment theory, neuroscience developmental psychology and cross-cultural studies, it weaves these into an accessible enjoyable text which always keeps in mind children recognisable to academics, practitioners and parents. It unpacks the most significant influences on the developing child, including the family and social context. It looks at key developmental stages from life in the womb to the pre-school years and right up until adolescence, covering important topics such as genes and environment, trauma, neglect or resilience. It also examines how children develop language, play and memory and, new to this edition, moral and prosocial capacities. Issues of nature and nurture are addressed and the effects of different kinds of early experiences are unpicked, creating a coherent and balanced view of the developing child in context. Nurturing Natures is written by an experienced child therapist who has used a wide array of research from different disciplines to create a highly readable and scientifically trustworthy text. This book should be essential reading for childcare students, for teachers, social workers, health visitors, early years practitioners and those training or working in child counselling, psychiatry and mental health. Full of fascinating findings, it provides answers to many of the questions people really want to ask about the human journey from conception into adulthood. .
