Endophytes and Secondary Metabolites

Endophytes and Secondary Metabolites
Author: Sumita Jha
Publisher: Springer
Total Pages: 0
Release: 2019-07-24
Genre: Science
ISBN: 9783319904832

This reference work presents an authoritative review of endophytes and their applications to human welfare. Endophytes have become a class of interesting and curious microorganisms due to their intimate intra- and intercellular association with plants for competence, survival and reproduction. They can be bacteria or fungi, and they are usually non-pathogenic to their host. Endophytes have important applications in agriculture and industry, namely, they can help with plant growth, act as biocontrol agents and biosurfactant and secondary metabolite producers, and they are also rich sources of bioactive natural products. Novel and beneficial effects of endophytes are constantly emerging, and this book, divided into four sections, provides readers with the latest developments in this fast expanding field. In the first section, readers will discover the biology of the major groups of endophytes, followed by a summary of conventional and molecular tools for endophytes’ identification in Section II. The production of high-value metabolites by endophytes will be explored in the third section of this book, and in the final section, readers will find several case studies, examples and prospects for endophytes’ application in agriculture and industry. Written by leading international authors, this reference work will appeal to a wide readership, from students and researchers in the field of botany, biotechnology and agriculture to professionals interested in the production and applications of endophytic metabolites.

Endophytic Fungi

Endophytic Fungi
Author: Evelyn Hughes
Publisher: Nova Science Publishers
Total Pages: 0
Release: 2016-12-31
Genre: Medical
ISBN: 9781536103410

Endophytic fungi are important biotechnological tools because they produce many secondary metabolites. However, to access this important source of bioactive molecules, it is essential to explore the diversity of endophytic fungi and catalog their species richness in different ecosystems. This book reviews the diversity, characterisation and biocontrol of endophytic fungi.

Volatiles and Metabolites of Microbes

Volatiles and Metabolites of Microbes
Author: Joginder Singh Panwar
Publisher: Academic Press
Total Pages: 513
Release: 2021-06-22
Genre: Science
ISBN: 0323851649

Volatiles and Metabolites of Microbes compiles the latest research and advancement in the field of volatiles, metabolites synthesized from the microbial strains such as actinomycetes, bacteria, cyanobacteria, and fungal species and their potential applications in the field of healthcare issue and sustainable agriculture. There is an urgent need to explore new and advanced biological methods for health industries and sustainable agriculture and to protect the environment from environmental pollution or contaminates, global warming, and also control the health of human beings from the side effects of various pharmaceuticals products. Focusing all these factors, Volatiles and Metabolites of Microbes explores new aspects of microorganism in terms of volatiles, enzymes, bioactive compounds synthesized from the microbes and their potential applications in the field of sustainable agriculture and health-related issues - Provides a broad aspect about volatiles, bioactive compounds, and secondary metabolites of microbes compiled in one cover - Gives the latest research and advancement in the field of volatiles, secondary metabolites, and bioactive compounds synthesized from the different microbial strains - Responds to new developments in the detection of the complex compound structures of volatiles - Offers insight to a very broad audience in Biotechnology, Applied Microbiology, Agronomy, and Pathology

Advances in Endophytic Fungal Research

Advances in Endophytic Fungal Research
Author: Bhim Pratap Singh
Publisher: Springer
Total Pages: 367
Release: 2019-02-12
Genre: Science
ISBN: 3030035891

Plant endophytes are a potential source for the production of bioactive compounds that can fight against devastating diseases in both plants and humans. Among these endophytic microorganisms, endophytic fungi are one of the dominant group of microorganisms with a potential role in plant growth promotion and the discovery of noble bioactive natural products. Endophytic fungi possess several bioactivities like anticancer, antimicrobial, insecticidal, plant growth stimulants, crop protection, phytoremediation, etc. Presence of modular biosynthetic genes clusters like PKS and NRPS in several endophytic fungi underscores the need to understand and explore such organisms. This volume presents and demonstrates the applied aspects of endophytic fungi. Practical applications of such endophytes are discussed in detail, including studies in pharmaceutical development and agricultural management of important microbial diseases. The beneficial effects that endophytic fungi provide to host plants—enhancing growth, increasing fitness, strengthening tolerance to abiotic and biotic stresses through secondary metabolites—are also discussed. The reader is provided with a comprehensive and detailed understanding of such relationships between endophytic fungi and their host.

Marine Microbial Diversity as a Source of Bioactive Natural Products

Marine Microbial Diversity as a Source of Bioactive Natural Products
Author: Didier Stien
Publisher: MDPI
Total Pages: 146
Release: 2020-06-17
Genre: Science
ISBN: 3039361821

A trillion different microbial species have been evolving for some 3.5 billion years, producing ever more complex active secondary metabolites. The sea is a cauldron of a great diversity of useful and valuable compounds. This Special Issue focused on studies of marine microbe natural products for discovering compounds useful to humankind. Papers were collected that provide up-to-date information regarding the characterization of marine microbes’ metabolic diversity and the evaluation of the therapeutic potential of marine microbes’ metabolites. Most of the articles in this book deal with marine fungi, biological and chemical diversity, and their active metabolites. This may be a sign that marine fungi have been under studied to date and are perceived by many researchers as an important source of discovery in this field. A best practices guide for the isolation of marine fungi from different matrixes and their conservation is also presented. The comparison of the phylogenetic and metabolomic profiles of microalgae from different lineages provides novel insights into the potential of chemotaxonomy in marine phytoplankton, showing a good overlap of phylogenetic and chemotaxonomic signals.

Endophytes for a Growing World

Endophytes for a Growing World
Author: Trevor R. Hodkinson
Publisher: Cambridge University Press
Total Pages: 445
Release: 2019-03-21
Genre: Business & Economics
ISBN: 1108471765

Discusses the role of endophytes in food security, forestry and health. It outlines their general biology, spanning theory to practice.

Recent Advancement in White Biotechnology Through Fungi

Recent Advancement in White Biotechnology Through Fungi
Author: Ajar Nath Yadav
Publisher: Springer
Total Pages: 517
Release: 2019-04-24
Genre: Science
ISBN: 3030148467

White biotechnology is industrial biotechnology dealing with various biotech products through applications of microbes. The main application of white biotechnology is commercial production of various useful organic substances, such as acetic acid, citric acid, acetone, glycerine, etc., and antibiotics like penicillin, streptomycin, mitomycin, etc., and value added product through the use of microorganisms especially fungi and bacteria. The value-added products included bioactive compounds, secondary metabolites, pigments and industrially important enzymes for potential applications in agriculture, pharmaceuticals, medicine and allied sectors for human welfare. In the 21st century, techniques were developed to harness fungi to protect human health (through antibiotics, antimicrobial, immunosuppressive agents, value-added products etc.), which led to industrial scale production of enzymes, alkaloids, detergents, acids, biosurfactants. The first large-scale industrial applications of modern biotechnology have been made in the areas of food and animal feed production (agricultural/green biotechnology) and pharmaceuticals (medical/red biotechnology). In contrast, the production of bio-active compounds through fermentation or enzymatic conversion is known industrial or white biotechnology. The beneficial fungal strains may play important role in agriculture, industry and the medical sectors. The beneficial fungi play a significance role in plant growth promotion, and soil fertility using both, direct (solubilization of phosphorus, potassium and zinc; production of indole acetic acid, gibberellic acid, cytokinin and siderophores) and indirect (production of hydrolytic enzymes, siderophores, ammonia, hydrogen cyanides and antibiotics) mechanisms of plant growth promotion for sustainable agriculture. The fungal strains and their products (enzymes, bio-active compounds and secondary metabolites) are very useful for industry. The discovery of antibiotics is a milestone in the development of white biotechnology. Since then, white biotechnology has steadily developed and now plays a key role in several industrial sectors, providing both high valued nutraceuticals and pharmaceutical products. The fungal strains and bio-active compounds also play important role in the environmental cleaning. This volume covers the latest research developments related to value-added products in white biotechnology through fungi.

Fungal Metabolites

Fungal Metabolites
Author: Jean-Michel Mérillon
Publisher: Springer
Total Pages: 0
Release: 2017-02-20
Genre: Science
ISBN: 9783319250007

This handbook compiles authoritative information about fungal metabolites and their chemistry and biotechnology. The first in the reference work series “Phytochemicals”, and written by a team of international expert authors, this book provides reference information ranging from the description of fungal natural products, over their use e.g. as anticancer agents, to microbial synthesis, even spanning to the production of secondary metabolites on industrial scale. On the other hand it also describes global health issues related to aflatoxin production in foods and agriculture, including perspectives for detoxification. The handbook characterizes different compound classes derived from fungal secondary metabolites, like ergot alkaloids and aflatoxins. The discussion puts a special emphasis on how potentially useful compounds can be obtained and what applications they can find, on the one hand, and how potential dangers can be encountered on the other hand. The comprehensive chapters in this handbook will thus appeal to readers from diverse backgrounds in chemistry, biology, life sciences, and even medicine, who are working or planning to work with fungal (secondary) metabolites and their application. They provide the readers with rich sources of reference information on important topics in this field.

Bioactive Natural products in Drug Discovery

Bioactive Natural products in Drug Discovery
Author: Joginder Singh
Publisher: Springer Nature
Total Pages: 722
Release: 2020-04-30
Genre: Medical
ISBN: 9811513945

This book highlights different natural products that are derived from the plants and microbes that have shown potential as the lead compounds against infectious diseases and cancer. Natural products represent an untapped source of strikingly diverse chemotypes with novel mechanisms of action and the potential to serve as anticancer and anti-infective agents. The book discusses a range of biotechnologically valuable bioactive compounds and secondary metabolites that have been derived from plant and microorganisms from various ecological niches. It also reviews the latest developments in the field of genomics, bioinformatics and industrial fermentation for harnessing the microbial products for commercial applications. In turn, the book’s closing section reviews important biotechnological applications of various natural products. Combining the expertise of specialists in this field, the book’s goal is to promote the further investigation of natural sources for the development of standardized, safe and effective therapies.

Trichoderma

Trichoderma
Author: Prasun K. Mukherjee
Publisher: CABI
Total Pages: 345
Release: 2013-09-16
Genre: Technology & Engineering
ISBN: 1780642474

Trichoderma spp. are biotechnologically significant fungi, being widely used both in agriculture and industry. These microbes are also a potential drug source of clinical importance. In recent years, driven by advances in genetics and genomics, research on these fungi have opened new avenues for its varied applications. Divided into three sections, covering taxonomy and physiology, interactions with plants and applications and significance, this book also discusses topics that have seen rapid developments in the recent years. Various aspects of Trichoderma like molecular taxonomy, sexual and asexual developments, secondary metabolism, beneficial interactions with plants, applications as cell factories and harmful interactions with humans are discussed. This book, thus, hopes to be an essential ready reference for researchers, students and people form industry as well.